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Cefaclor

Cefaclor is an antibiotic drug, more specifically, a cephalosporin antibiotic. It's used to treat a variety of bacterial infections, ranging from ear and respiratory infections to skin infections. Some common side effects include diarrhea, nausea, and a rash, but your healthcare provider will always weigh the benefits against potential side effects.

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Frequently Asked Questions

Can I drink alcohol while taking Cefaclor?
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Yes, you can drink alcohol while taking cefaclor. However, excessive alcohol consumption might worsen the side effects like dizziness and upset stomach.

Can I take cefaclor if I'm allergic to penicillin?
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A small number of people who are allergic to penicillin also react to cephalosporins, including cefaclor. Always inform your healthcare provider if you have had previous allergic reactions to antibiotics.

I missed a dose of Cefaclor, what should I do?
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Take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

Comprehensive Drug Guide

How Does Cefaclor Work?

Cefaclor is a bactericidal antibiotic and works by disrupting the growth of the bacterial cell wall, leading to the death of the bacteria.

What is Cefaclor Used For?

FDA indications: Cefaclor is used to treat a variety of bacterial infections, like respiratory tract infections, skin and skin structure infections, and urinary tract infections, among others.

Offlabel uses: It's also used offlabel for the treatment of Lyme disease and impetigo.

Common Dosages

Capsules: 250mg, 500mg

Suspension: 125mg/5ml, 250mg/5ml

Typical Dosing

FDA Approved Indications

  • For FDAapproved indications:
  • Respiratory tract infections 250mg to 500mg every 8 hours.
  • Skin and skin structure infections 375mg to 500mg every 8 hours.
  • Urinary tract infections 250mg every 12 hours.

Off-Label Uses

  • For offlabel uses:
  • Lyme disease: 500mg every 8 hours.
  • Impetigo: 250mg to 375mg every 8 hours.

Who Shouldn't Take Cefaclor?

  • Anyone who has had a serious allergic reaction to cefaclor or other cephalosporin antibiotics.
  • Those with a history of colitis or other severe intestinal disorders.
  • Pregnant or breastfeeding women, unless under the supervision of a doctor.
  • People with kidney problems should use it with caution and under the guidance of a healthcare provider.

Advice From The Pharmacist

  • Remember to take Cefaclor at even intervals throughout the day to keep a consistent level in your body.
  • Finish your entire course of treatment, even if you start feeling better, to fully clear the infection and prevent a relapse.
  • If diarrhea persists or worsens, notify your doctor.

Side Effects of Cefaclor

Common Side Effects

  • You might have diarrhea, nausea, or vomiting.
  • You might develop a rash, itchiness, or hives.
  • You might experience dizziness, somnolence, or headache.

Uncommon/Severe Side Effects

  • Uncommon side effects:
  • You may develop a condition called pseudomembranous colitis.
  • You might experience increased liver markers.
  • Rare side effects:
  • You might have severe anaphylactic reactions leading to shock.
  • Severe skin reactions like StevensJohnson syndrome or exfoliative dermatitis could occur.
  • Symptoms of meningitis such as headache, fever, or stiff neck.
  • Severe side effects:
  • Seizures, hallucinations, or severe confusion.
  • Bloody or watery diarrhea.
  • Chest pain, difficulty breathing, or a severe skin rash (these symptoms deserve immediate medical attention).

Risks and Warnings of Cefaclor

  • Severe allergic reactions can occur. Use with caution for those with a history of allergies.
  • Pseudomembranous colitis can be a potential concern due to the change in gut flora.
  • Use with caution in patients with gastrointestinal diseases, particularly colitis.
  • Use with caution in patients with a history of kidney disease.
  • Overuse or misuse can lead to antibiotic resistance.
  • It's not known if cefaclor is safe or effective in neonates or infants less than onemonthold.

Interactions with Cefaclor

Common Drug Interactions

  • Probenecid
  • Vaccines

Alternatives to Cefaclor

  • Cephalexin
  • Amoxicillin
  • Azithromycin
  • Ciprofloxacin
  • Doxycycline