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Aviane
Aviane is a combination oral contraceptive containing ethinyl estradiol and levonorgestrel, two hormones that prevent pregnancy. It works by preventing ovulation, altering the cervical mucus to make it more difficult for sperm to reach the uterus, and changing the uterine lining to prevent a fertilized egg from attaching. Aviane is primarily used for birth control, but it may also be prescribed to regulate menstrual cycles and treat conditions like acne and polycystic ovary syndrome (PCOS).
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Frequently Asked Questions
Can Aviane cause weight gain?
Some women may experience slight weight gain due to water retention when using Aviane, but significant weight changes are uncommon.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more active pills, follow the instructions in the patient leaflet or consult your healthcare provider, as backup contraception may be needed.
Can Aviane help with acne?
Yes, Aviane is sometimes prescribed off-label to help with acne. The hormones in the pill can help reduce sebum production and improve acne in some patients.
Is it safe to take Aviane while breastfeeding?
It is generally not recommended to take combination oral contraceptives like Aviane while breastfeeding, as they may reduce milk supply. Progestin-only options may be better choices for breastfeeding women.
Does Aviane protect against sexually transmitted infections (STIs)?
No, Aviane does not protect against STIs. Use condoms or other barrier methods to protect against sexually transmitted infections while using Aviane for contraception.
Comprehensive Drug Guide
How Does Aviane Work?
Aviane prevents pregnancy through three mechanisms. It stops the release of an egg (ovulation) by suppressing the hormones that trigger the release of an egg from the ovaries. It also thickens cervical mucus, making it more difficult for sperm to reach the egg, and changes the uterine lining to prevent the implantation of a fertilized egg.
Common Dosages
- Oral tablets: 21 active tablets containing 0.1 mg levonorgestrel and 0.02 mg ethinyl estradiol, plus 7 inactive (placebo) tablets.
Typical Dosing
- For contraception: Take one active tablet daily for 21 consecutive days, followed by one inactive tablet daily for 7 days. A new pack should be started after the completion of the 28-day cycle.
Typical Dosing
FDA Approved Indications
- Contraception to prevent pregnancy
Who Shouldn't Take Aviane?
- Known hypersensitivity to ethinyl estradiol, levonorgestrel, or any component of the formulation.
- History of blood clots, stroke, or heart attack.
- Uncontrolled high blood pressure.
- Liver disease.
- Pregnancy.
- Breast cancer or other hormone-sensitive cancers.
Advice From The Pharmacist
- Take Aviane at the same time every day to maintain consistent hormone levels and maximize its effectiveness.
- If you miss a dose, refer to the patient information leaflet for guidance on what to do based on how many pills were missed. Backup contraception (such as condoms) may be needed if doses are missed.
- Be aware that Aviane does not protect against sexually transmitted infections (STIs); use barrier methods like condoms for protection against STIs.
- Some medications, such as antibiotics and certain seizure medications, may reduce the effectiveness of Aviane. Always inform your healthcare provider of all medications you are taking.
Side Effects of Aviane
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Mood changes
- Breakthrough bleeding (spotting between periods)
Uncommon/Severe Side Effects
- Blood clots, especially in the legs (deep vein thrombosis) or lungs (pulmonary embolism)
- Stroke
- High blood pressure
- Liver problems
Risks and Warnings of Aviane
- Blood Clot Risk: Combination oral contraceptives like Aviane increase the risk of blood clots, particularly in women who smoke and are over the age of 35. Avoid smoking while taking Aviane to reduce this risk.
- Cancer Risk: Aviane may slightly increase the risk of breast and cervical cancers. Routine screenings are recommended for women taking hormonal contraceptives.
- Liver Disease: Aviane should not be used by women with severe liver disease, as it can worsen liver function.
Interactions with Aviane
Common Drug Interactions
- Antibiotics: Certain antibiotics, such as rifampin, can decrease the effectiveness of Aviane. Use backup contraception while taking these medications.
- Antiepileptic drugs: Some seizure medications may reduce the effectiveness of Aviane, necessitating additional contraceptive measures.
- Herbal supplements: St. John's Wort may reduce the effectiveness of Aviane and lead to unintended pregnancy.
Alternatives to Aviane
- Ortho Tri-Cyclen (ethinyl estradiol and norgestimate): A combination oral contraceptive used for birth control and acne treatment.
- Lo Loestrin Fe (ethinyl estradiol and norethindrone): A low-dose combination oral contraceptive.
- Depo-Provera (medroxyprogesterone acetate): An injectable contraceptive administered every three months.
- Nexplanon: A contraceptive implant that lasts for up to three years.
