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Lo Loestrin Fe

Lo Loestrin Fe is a combination oral contraceptive that contains ethinyl estradiol and norethindrone acetate, along with iron supplementation. It is primarily used for the prevention of pregnancy and may also help manage menstrual disorders. This formulation is designed to provide effective contraception with a lower dosage of hormones, which may be beneficial for women sensitive to higher hormone levels.



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Frequently Asked Questions

How effective is Lo Loestrin Fe at preventing pregnancy?
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When taken as directed, Lo Loestrin Fe is over 99% effective at preventing pregnancy.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Can I use Lo Loestrin Fe while breastfeeding?
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Consult your healthcare provider about the use of hormonal contraceptives while breastfeeding, as some may not be recommended.

Will Lo Loestrin Fe affect my menstrual cycle?
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Some women experience lighter periods or changes in their menstrual cycle while using Lo Loestrin Fe.

Is it safe to smoke while taking Lo Loestrin Fe?
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Smoking increases the risk of serious cardiovascular side effects. It is advisable to quit smoking before starting any hormonal contraceptive.

Comprehensive Drug Guide

How Does Lo Loestrin Fe Work?

Lo Loestrin Fe works by inhibiting ovulation, altering the cervical mucus to impede sperm movement, and changing the uterine lining to reduce the likelihood of implantation. The low dose of hormones helps minimize potential side effects while maintaining contraceptive effectiveness.

Common Dosages

  • Active Tablets: Each active tablet contains 10 mcg of ethinyl estradiol and 1 mg of norethindrone.
  • Inactive Tablets: These include 2 placebo tablets and 1 iron tablet.

Typical Dosing

  • Take one active tablet daily for 24 days, followed by two inactive tablets and one iron tablet to complete the 26-day cycle.
  • It is important to take the tablets at the same time each day for maximum effectiveness.


Typical Dosing

FDA Approved Indications

  • Prevention of Pregnancy: as an oral contraceptive.
  • Management of Menstrual Disorders: to help regulate menstrual cycles and reduce heavy bleeding.


Who Shouldn't Take Lo Loestrin Fe?

  • Known hypersensitivity to ethinyl estradiol, norethindrone, or any component of the formulation.
  • History of thromboembolic disorders, stroke, or heart disease.
  • Severe liver disease or certain cancers, such as breast cancer.


Advice From The Pharmacist

  • Use a backup contraceptive method (e.g., condoms) during the first 7 days of starting Lo Loestrin Fe if it is your first time using hormonal contraception.
  • Inform your healthcare provider of any other medications you are taking, as some can interact with Lo Loestrin Fe.
  • Monitor for any unusual side effects and report them to your healthcare provider.


Side Effects of Lo Loestrin Fe

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headaches
  • Mood changes
  • Spotting or breakthrough bleeding


Uncommon/Severe Side Effects

  • Signs of a blood clot (swelling, pain in the legs, sudden shortness of breath).
  • Severe headache or vision changes.
  • Signs of liver dysfunction (jaundice, severe abdominal pain).


Risks and Warnings of Lo Loestrin Fe

  • Cardiovascular Risk: Hormonal contraceptives can increase the risk of blood clots, especially in smokers and women over 35.
  • Liver Health: Regular monitoring may be required for women with liver issues.
  • Missed Doses: Be aware of what to do if you miss a dose, as this can affect contraceptive effectiveness.


Interactions with Lo Loestrin Fe

Common Drug Interactions

  • Antibiotics: Some antibiotics may reduce the effectiveness of Lo Loestrin Fe.
  • Antiepileptic Drugs: Certain medications for seizures can affect hormone levels.
  • St. John’s Wort: This herbal supplement may decrease the effectiveness of hormonal contraceptives.


Alternatives to Lo Loestrin Fe

  • Other Oral Contraceptives: Different formulations may be recommended based on individual health needs and side effects.
  • Long-Acting Reversible Contraceptives (LARCs): Such as IUDs or implants.
  • Barrier Methods: Such as condoms or diaphragms for contraception.