Aptensio XR

For FDA-approved indications:

• ADHD in children and adults: 10 to 60mg per day.

For off-label uses:

• Narcolepsy: Dosage varies based on the severity of the condition and will be determined by the healthcare provider.

Aptensio XR should not be used in individuals with a known hypersensitivity to methylphenidate or other ingredients in the formulation. It is also contraindicated in patients with severe anxiety, tension, or agitation, as well as those with glaucoma, tics, or a history of Tourette's syndrome. Patients who are currently taking or have recently taken monoamine oxidase inhibitors (MAOIs) should avoid Aptensio XR due to the risk of hypertensive crisis.

When taking Aptensio XR, it’s important to take the medication in the morning to avoid interference with sleep. Swallow the capsule whole, or if necessary, sprinkle the contents on a small amount of applesauce and consume immediately without chewing. Avoid taking the medication late in the day, as it can cause difficulty sleeping. Regular monitoring by your healthcare provider is important, as they may need to adjust the dosage based on your response to the medication. Additionally, avoid consuming large amounts of caffeine, as it can increase side effects such as nervousness and jitteriness.

Common side effects of Aptensio XR include decreased appetite, insomnia, stomach pain, headache, and irritability. More serious side effects may include increased blood pressure, rapid heart rate, mood changes, and potential signs of dependence or abuse. If you experience chest pain, shortness of breath, severe anxiety, or signs of an allergic reaction (e.g., rash, swelling, difficulty breathing), seek medical attention immediately.

Aptensio XR carries a risk of abuse, dependence, and misuse, particularly in individuals with a history of substance abuse. It is classified as a Schedule II controlled substance due to its potential for abuse. The medication can also increase the risk of cardiovascular events, particularly in patients with pre-existing heart conditions. Regular monitoring by a healthcare provider is essential while on this medication, especially for heart health and growth in children. Long-term use of stimulants may affect growth, so children on Aptensio XR should have their height and weight regularly monitored.

Aptensio XR may interact with several other medications, including monoamine oxidase inhibitors (MAOIs), blood pressure medications, and certain antidepressants. It is also important to avoid alcohol while taking this medication, as it can alter the release mechanism of the extended-release formulation and increase the risk of side effects. Always inform your healthcare provider of all medications and supplements you are taking before starting Aptensio XR.

Alternative treatments to Aptensio XR for attention deficit hyperactivity disorder (ADHD) may include other extended-release stimulants such as Concerta (methylphenidate), Adderall XR (amphetamine), or non-stimulant options like atomoxetine (Strattera) or guanfacine (Intuniv). Behavioral therapy and lifestyle modifications may also be considered as part of a comprehensive treatment plan.