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Amoxicillin-Pot Clavulanate ER

Amoxicillin-Pot Clavulanate ER, the generic version of Augmentin XR, is a combination antibiotic medication. It is prescribed for the treatment of various bacterial infections, including respiratory infections, sinusitis, urinary tract infections, and skin infections. The drug belongs to the penicillin class of antibiotics. Amoxicillin works by inhibiting the growth of bacteria, while clavulanate potassium helps prevent certain bacteria from becoming resistant to amoxicillin. This extended-release formulation allows for sustained antibiotic levels in the body, making it effective in managing infections over a longer period.



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Frequently Asked Questions

Can I take Amoxicillin-Pot Clavulanate ER if I'm allergic to penicillin?
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No, if you are allergic to penicillin or cephalosporins, you should avoid taking Amoxicillin-Pot Clavulanate ER and consult your healthcare provider for an alternative treatment.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Can I drink alcohol while taking this medication?
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It's best to avoid alcohol while taking Amoxicillin-Pot Clavulanate ER, as it may increase the likelihood of side effects such as nausea and liver issues.

How should I store this medication?
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Store Amoxicillin-Pot Clavulanate ER tablets at room temperature, away from moisture and heat. Keep the medication in its original packaging until you're ready to take it.

Can I take this medication if I'm pregnant or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding before taking Amoxicillin-Pot Clavulanate ER. While it is generally considered safe, your doctor will weigh the benefits and risks specific to your situation.

Comprehensive Drug Guide

How Does Amoxicillin-Pot Clavulanate ER Work?

Amoxicillin-Pot Clavulanate ER works by attacking the bacteria that cause infections. Amoxicillin interferes with the bacteria's ability to form cell walls, which are essential for their survival. Clavulanate prevents bacteria from resisting the effects of amoxicillin, making the combination more effective in treating infections.

Common Dosages

Amoxicillin-Pot Clavulanate ER is available in extended-release tablet form, commonly in two strengths:

  • 1000 mg/62.5 mg per tablet (Amoxicillin 1000 mg and Clavulanate Potassium 62.5 mg)
  • 775 mg/62.5 mg per tablet (Amoxicillin 775 mg and Clavulanate Potassium 62.5 mg)

These dosages allow for flexibility in treatment, depending on the severity of the infection and the patient's response to therapy.


Typical Dosing


For adults and children over 16 years of age, the typical dosing of Amoxicillin-Pot Clavulanate ER is 2000 mg/125 mg every 12 hours for 7 to 10 days, depending on the infection being treated. The extended-release formulation is typically prescribed for more severe infections, such as sinusitis or pneumonia. For pediatric dosing, this medication is generally not recommended due to the specific dosing needs and formulation constraints.



Advice From The Pharmacist

When taking Amoxicillin-Pot Clavulanate ER, it’s important to take the medication at the start of a meal to reduce the likelihood of gastrointestinal discomfort. Avoid consuming alcohol while on this medication, as it may exacerbate side effects such as nausea and dizziness. If you experience severe diarrhea, abdominal pain, or a rash, contact your healthcare provider immediately. Always complete the full course of antibiotics, even if you start feeling better before the treatment is finished.



Side Effects of Amoxicillin-Pot Clavulanate ER

Common Side Effects

Common side effects of Amoxicillin-Pot Clavulanate ER include nausea, vomiting, diarrhea, and skin rash. Serious side effects may include severe allergic reactions, liver problems, and Clostridioides difficile-associated diarrhea. If you experience any unusual symptoms, such as yellowing of the skin or eyes, persistent diarrhea, or signs of a severe allergic reaction (e.g., swelling, difficulty breathing), seek medical attention right away.



Risks and Warnings of Amoxicillin-Pot Clavulanate ER

The major risks associated with Amoxicillin-Pot Clavulanate ER include allergic reactions, liver dysfunction, and the potential for antibiotic-associated diarrhea, which could be severe. It's essential to inform your healthcare provider of any past allergic reactions to antibiotics or any history of liver disease before starting this medication. Overuse or misuse of antibiotics can lead to antibiotic resistance, so it's critical to take this medication only as prescribed.



Interactions with Amoxicillin-Pot Clavulanate ER

Common Drug Interactions

Amoxicillin-Pot Clavulanate ER may interact with several other medications, including blood thinners like warfarin, methotrexate, and other antibiotics. Additionally, it can reduce the effectiveness of oral contraceptives. It's also essential to avoid combining this drug with alcohol, as it can increase the risk of liver damage and gastrointestinal side effects. Individuals with a penicillin allergy should avoid this medication.



Alternatives to Amoxicillin-Pot Clavulanate ER

Alternative medications to Amoxicillin-Pot Clavulanate ER include other antibiotics such as doxycycline, azithromycin, or cephalexin, depending on the infection being treated and the patient's tolerance to other medications. If a patient cannot take penicillin-based antibiotics, macrolides or fluoroquinolones may be considered as alternatives.