You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Amoxicillin-Pot Clavulanate
Amoxicillin-Pot Clavulanate, commonly known as Augmentin, is a combination antibiotic used to treat a wide range of bacterial infections. Amoxicillin is a penicillin antibiotic that works by inhibiting the formation of bacterial cell walls, leading to the destruction of bacteria. Potassium clavulanate, a beta-lactamase inhibitor, prevents certain bacteria from becoming resistant to amoxicillin by inhibiting the beta-lactamase enzyme they produce. This combination is effective against a broader spectrum of bacteria than amoxicillin alone, making it useful for treating more complex infections.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Amoxicillin-Pot Clavulanate ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
Can Amoxicillin-Pot Clavulanate be used to treat viral infections?
No, Amoxicillin-Pot Clavulanate is an antibiotic and is not effective against viral infections such as the common cold or flu. It should only be used for bacterial infections as prescribed by a healthcare provider.
How should Amoxicillin-Pot Clavulanate be stored?
Store Amoxicillin-Pot Clavulanate tablets at room temperature, away from moisture and heat. The oral suspension should be refrigerated and used within 10 days of preparation.
Is Amoxicillin-Pot Clavulanate safe during pregnancy?
Amoxicillin-Pot Clavulanate is generally considered safe for use during pregnancy, but it should be used only if clearly needed. Consult your healthcare provider for advice.
What should I do if I miss a dose of Amoxicillin-Pot Clavulanate?
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses to make up for a missed one.
Comprehensive Drug Guide
How Does Amoxicillin-Pot Clavulanate Work?
Amoxicillin-Pot Clavulanate works by combining the actions of two agents. Amoxicillin inhibits bacterial cell wall synthesis, leading to the death of bacteria. However, some bacteria produce an enzyme called beta-lactamase, which can inactivate amoxicillin. Clavulanate inhibits this enzyme, allowing amoxicillin to remain effective against beta-lactamase-producing bacteria. This combination extends the antibiotic's spectrum of activity, making it effective against both beta-lactamase-producing and non-beta-lactamase-producing bacteria.
Common Dosages
Amoxicillin-Pot Clavulanate is commonly available in the following dosages:
- 250 mg/125 mg tablets
- 500 mg/125 mg tablets
- 875 mg/125 mg tablets
- 200 mg/28.5 mg per 5 mL suspension
- 400 mg/57 mg per 5 mL suspension
Typical Dosing
The typical dosing for Amoxicillin-Pot Clavulanate varies based on the severity and type of infection:
- Adults: 500 mg/125 mg every 12 hours or 875 mg/125 mg every 12 hours, depending on the severity of the infection.
- Children: Dosing is based on body weight, typically 20-40 mg/kg/day of amoxicillin, divided into two or three doses.
Dosage adjustments may be necessary for patients with renal impairment.
Typical Dosing
FDA Approved Indications
Amoxicillin-Pot Clavulanate is FDA-approved for the treatment of:
- Sinusitis
- Otitis media (middle ear infection)
- Lower respiratory tract infections (e.g., bronchitis, pneumonia)
- Urinary tract infections (UTIs)
- Skin and soft tissue infections
- Bite wounds (e.g., animal or human bites)
Who Shouldn't Take Amoxicillin-Pot Clavulanate?
Amoxicillin-Pot Clavulanate should not be used in patients with:
- A history of severe allergic reactions (e.g., anaphylaxis) to amoxicillin, penicillins, or other beta-lactam antibiotics
- A history of liver dysfunction or cholestatic jaundice associated with previous use of this combination
Advice From The Pharmacist
Patients taking Amoxicillin-Pot Clavulanate should:
- Take the medication exactly as prescribed and complete the full course of therapy, even if symptoms improve before finishing the medication.
- Take the medication with food to reduce the risk of gastrointestinal upset.
- Store the oral suspension in the refrigerator and shake well before each use. Discard any unused suspension after 10 days.
- Be aware of the potential for allergic reactions, including rash, itching, and difficulty breathing, and seek immediate medical attention if these occur.
Side Effects of Amoxicillin-Pot Clavulanate
Common Side Effects
Common side effects of Amoxicillin-Pot Clavulanate include:
- Nausea
- Diarrhea
- Rash
- Vomiting
Uncommon/Severe Side Effects
Serious side effects may include:
- Severe allergic reactions (anaphylaxis)
- Clostridium difficile-associated diarrhea
- Liver dysfunction (e.g., elevated liver enzymes, jaundice)
- Stevens-Johnson syndrome (rare)
Risks and Warnings of Amoxicillin-Pot Clavulanate
Major risks and warnings associated with Amoxicillin-Pot Clavulanate include:
- Allergic Reactions: Patients with a history of penicillin allergy may be at increased risk of severe allergic reactions. Cross-reactivity with other beta-lactam antibiotics may occur.
- Hepatotoxicity: The combination of amoxicillin and clavulanate has been associated with liver dysfunction, including cholestatic jaundice. Liver function should be monitored in patients with preexisting liver conditions.
- Antibiotic-Associated Diarrhea: Amoxicillin-Pot Clavulanate may cause Clostridium difficile-associated diarrhea, which can be severe and lead to colitis.
Interactions with Amoxicillin-Pot Clavulanate
Common Drug Interactions
Amoxicillin-Pot Clavulanate may interact with:
- Oral Contraceptives: Reduced effectiveness of birth control pills; consider using additional contraception.
- Allopurinol: Increased risk of rash when used with Amoxicillin-Pot Clavulanate.
- Probenecid: May increase blood levels of amoxicillin by reducing renal excretion.
Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential drug interactions.
Alternatives to Amoxicillin-Pot Clavulanate
Alternative medications to Amoxicillin-Pot Clavulanate include:
- Cephalexin: A first-generation cephalosporin antibiotic for similar bacterial infections.
- Doxycycline: A tetracycline antibiotic used for respiratory and skin infections, especially in penicillin-allergic patients.
- Clindamycin: An antibiotic used for anaerobic infections and as an alternative in penicillin-allergic patients.
