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Adzenys ER

Adzenys ER is an extended-release oral suspension of amphetamine, a central nervous system (CNS) stimulant used to treat attention-deficit hyperactivity disorder (ADHD) in children and adults. Amphetamine works by increasing the levels of neurotransmitters dopamine and norepinephrine in the brain, which helps improve focus, attention, and impulse control. Adzenys ER provides a long-lasting effect, making it a convenient once-daily treatment option for managing ADHD symptoms throughout the day.


Adzenys ER is available by prescription only and comes in an extended-release oral suspension. It is classified as a Schedule II controlled substance due to its potential for abuse and dependence. Because of these risks, patients prescribed Adzenys ER should be closely monitored by their healthcare provider, and the medication should be used exactly as directed.


Adzenys ER belongs to the formal drug class of central nervous system (CNS) stimulants. Informally, it may be referred to as an ADHD medication or a stimulant. These classifications relate to its function in enhancing focus, attention, and impulse control in individuals with ADHD.




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Frequently Asked Questions

How long does it take for Adzenys ER to start working?
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Adzenys ER typically begins to work within 1-2 hours after taking the dose, with effects lasting throughout the day due to its extended-release formulation.

Can Adzenys ER be taken with food?
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Yes, Adzenys ER can be taken with or without food. However, taking it with food may help reduce stomach discomfort.

What should I do if I miss a dose of Adzenys ER?
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If you miss a dose, take it as soon as you remember, but avoid taking it late in the day to prevent sleep disturbances. If it is close to the next scheduled dose, skip the missed dose and continue wit

Can Adzenys ER be used in children?
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Yes, Adzenys ER is approved for use in children aged 6 years and older. The dosage will be carefully adjusted based on the child’s response and tolerance.

Are there any dietary restrictions while taking Adzenys ER?
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There are no specific dietary restrictions, but it is important to maintain a healthy diet, as Adzenys ER can reduce appetite, potentially affecting growth in children.

Comprehensive Drug Guide

How Does Adzenys ER Work?

Adzenys ER works by increasing the levels of dopamine and norepinephrine in the brain by blocking their reuptake and promoting their release. These neurotransmitters play key roles in regulating attention, behavior, and mood. By enhancing their activity, Adzenys ER helps improve symptoms of ADHD, such as inattention, hyperactivity, and impulsivity. The extended-release formulation ensures a steady release of the medication throughout the day, providing sustained symptom control.

What is Adzenys ER Used For?


Common Dosages

Adzenys ER is available in an extended-release oral suspension with a concentration of 1.25 mg/mL. The dosage is individualized based on the patient’s age, weight, and response to treatment, with regular adjustments as needed. The medication is typically started at a lower dose and gradually increased.


The typical dosing for Adzenys ER involves taking the oral suspension once daily in the morning, with or without food. The dose may be adjusted based on the patient’s response and tolerance. It is important to shake the bottle well before each dose and measure the dose accurately using a dosing syringe or cup. Avoid taking the medication late in the day to prevent insomnia.



Typical Dosing

FDA Approved Indications

Adzenys ER is FDA-approved for the treatment of attention-deficit hyperactivity disorder (ADHD) in patients aged 6 years and older. It is intended to be part of a comprehensive treatment plan that includes psychological, educational, and social measures.



Off-Label Uses


Who Shouldn't Take Adzenys ER?

Adzenys ER should not be used in individuals who:

  • Have a known hypersensitivity to amphetamine or any of the components in the formulation
  • Have a history of cardiovascular disease, including severe hypertension or arrhythmias
  • Have hyperthyroidism or glaucoma
  • Have a history of drug abuse
  • Are currently taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping such treatment


Advice From The Pharmacist

When taking Adzenys ER, it is important to follow the prescribed dosing schedule closely and to measure the dose accurately. Be aware of potential side effects, such as increased heart rate and blood pressure, and report any unusual symptoms to your healthcare provider. Regular follow-up appointments are essential to monitor the effectiveness of the medication and to adjust the dosage as necessary. If a dose is missed, take it as soon as you remember, but avoid taking it late in the day to prevent sleep disturbances.



Side Effects of Adzenys ER

Common Side Effects

Common side effects of Adzenys ER may include:

  • Decreased appetite
  • Insomnia
  • Dry mouth
  • Headache
  • Nervousness or anxiety
  • Stomach pain
  • Increased heart rate


Uncommon/Severe Side Effects

Serious side effects, though rare, may include:

  • Chest pain
  • Shortness of breath
  • Severe hypertension
  • Hallucinations or psychotic symptoms
  • Seizures

If any serious side effects occur, seek medical attention immediately.



Risks and Warnings of Adzenys ER

  • Amphetamine can lead to an increased heart rate and blood pressure, making it unsuitable for people with heart conditions.
  • People with a history of drug addiction should also avoid it due to the high risk of dependency.
  • If you're going through pregnancy or planning to become pregnant, consult your doctor since the effects of amphetamine on the unborn baby aren't known.
  • Use caution if you have seizures or epilepsy, as amphetamine can induce seizures in some people.
  • If you have an overactive thyroid glaucoma or an overexcited state, amphetamine use may not be suitable.
  • Finally, individuals who have taken MAOIs within the last two weeks should not use amphetamine due to the risk of severe, life-threatening side effects.

Interactions with Adzenys ER

Common Drug Interactions

Adzenys ER can interact with several medications, including:

  • Monoamine oxidase inhibitors (MAOIs)
  • Antihypertensive medications
  • Antipsychotics
  • Tricyclic antidepressants
  • Proton pump inhibitors (PPIs)

These interactions can increase the risk of side effects or reduce the effectiveness of the medication. It is important to inform your healthcare provider of all medications, supplements, and over-the-counter products you are taking to avoid potential interactions.



Alternatives to Adzenys ER

Alternative treatments for ADHD include other stimulant medications such as Adderall (amphetamine salts), Vyvanse (lisdexamfetamine), and Concerta (methylphenidate). Non-stimulant options like Strattera (atomoxetine) and Intuniv (guanfacine) may also be considered, depending on the patient’s needs and response to treatment. Behavioral therapies and lifestyle interventions should also be part of the overall treatment plan.