Browse Medications by Drug Class: Leukotriene Receptor Antagonists

Written by Amar Lunagaria
Pharm.D • NiHowdy Founder

Reviewed by James Wong
Pharm.D • NiHowdy Founder
Published Jan 15, 2025

What are Leukotriene Receptor Antagonists?
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List of drugs in Leukotriene Receptor Antagonists
Drug Name | More Information | NiHowdy Prices & Bitcoin Rebate |
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Accolate | Accolate Information | Accolate Pricing |
Montelukast Sodium | Montelukast Sodium Information | Montelukast Sodium Pricing |
Singulair | Singulair Information | Singulair Pricing |
Zafirlukast | Zafirlukast Information | Zafirlukast Pricing |
Brief history about Leukotriene Receptor Antagonists?
How do Leukotriene Receptor Antagonists work?
What are Leukotriene Receptor Antagonists used to treat?
Asthma
LTRAs are used to manage mild to moderate asthma by reducing inflammation and preventing bronchoconstriction. They are particularly effective for controlling nighttime symptoms, preventing exercise-induced bronchospasm, and serving as an add-on therapy for patients who do not achieve full symptom control with inhaled corticosteroids.
Allergic Rhinitis
In allergic rhinitis, LTRAs reduce nasal congestion, sneezing, and runny nose by targeting the inflammatory pathways activated by allergens. These medications are especially useful for patients who have concurrent asthma and allergies, providing comprehensive relief for both conditions.
Exercise-Induced Bronchoconstriction
LTRAs are effective in preventing exercise-induced bronchoconstriction by relaxing airway muscles and reducing inflammation triggered by physical activity. They are a convenient oral option for individuals seeking to maintain an active lifestyle without respiratory limitations.
Who should consider Leukotriene Receptor Antagonists medications?
Adults
Adults with asthma, allergic rhinitis, or overlapping respiratory conditions benefit from LTRAs as part of their treatment plan. These medications provide an oral alternative for patients who prefer not to use inhalers or need additional control alongside inhaled corticosteroids. Adults with exercise-induced bronchoconstriction or aspirin sensitivity also find LTRAs particularly helpful in managing their symptoms.
Children
LTRAs are approved for use in pediatric populations as young as six months old, making them a safe and effective option for managing asthma and allergic rhinitis in children. These medications improve nighttime symptoms, reduce reliance on rescue inhalers, and support better participation in daily activities. Their palatable formulations, such as chewable tablets, enhance compliance in younger patients.
Seniors
Seniors with respiratory conditions benefit from the safety and convenience of LTRAs, particularly if they experience difficulty using inhalers due to arthritis or other mobility issues. These medications provide effective symptom control while minimizing the risk of systemic side effects. Regular monitoring ensures optimal dosing and safety in this population, considering potential interactions with other medications commonly used by seniors.
Are Leukotriene Receptor Antagonists safe?
Can I take Leukotriene Receptor Antagonists during pregnancy?
Are Leukotriene Receptor Antagonists safe to take while lactating?
Are Leukotriene Receptor Antagonists controlled substances?
Side effects of Leukotriene Receptor Antagonists?
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