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Montelukast Sodium
Montelukast sodium is a leukotriene receptor antagonist used to manage and prevent asthma symptoms and to relieve seasonal allergic rhinitis (hay fever). It works by blocking the action of leukotrienes, substances in the body that contribute to inflammation, bronchoconstriction, and mucus production, thereby improving respiratory function and reducing allergy symptoms.
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Frequently Asked Questions
Can I take Montelukast with allergy medication?
Yes, Montelukast is often used concomitantly with other allergy medications for better control of symptoms. However, dosage and timing should be properly supervised by a healthcare provider.
How quickly does montelukast sodium work?
Montelukast can begin to reduce asthma symptoms within 24 hours, but it may take several weeks to see the full benefit for asthma control.
Can I take montelukast sodium with food?
Yes, montelukast can be taken with or without food, making it convenient for most patients.
Can I take montelukast sodium with food?
Yes, montelukast can be taken with or without food, making it convenient for most patients.
What should I do if I miss a dose?
If it's not too close to the time for your next dose, then take the missed dose as soon as you remember. But if it's near the time for your next dose, then just skip the missed one and continue your dosing schedule. Don't intake double doses.
Can Montelukast help with shortness of breath?
Absolutely. Montelukast is designed to control and prevent symptoms of asthma such as wheezing and shortness of breath.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up dose
Are there any dietary restrictions while using montelukast sodium?
There are no specific dietary restrictions while using montelukast, but maintaining a balanced diet is advisable for overall health.
I'm feeling anxious, could this be due to Montelukast?
It's possible; Montelukast side effects could include trouble sleeping, behavior and mood changes such as anxiety, agitation, and suicidal thoughts. If you feel this way, it's crucial to talk to your healthcare provider immediately.
Can I have a glass of wine while on Montelukast?
The interaction between Montelukast and alcohol is considered moderate. This means that alcohol can exacerbate the side effects of Montelukast. It's recommended to speak to your doctor about this.
Is montelukast sodium safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using montelukast sodium.
Comprehensive Drug Guide
How Does Montelukast Sodium Work?
Montelukast works by selectively inhibiting the binding of leukotrienes to their receptors (CysLT1), which leads to decreased bronchoconstriction, reduced inflammation, and decreased mucus secretion in the airways. This helps in managing asthma and alleviating allergy symptoms.
What is Montelukast Sodium Used For?
Montelukast is primarily used in the chronic treatment and prophylaxis of asthma, exercise-induced bronchospasm, and relief of symptoms of allergic rhinitis (seasonal and perennial).
It has off-label uses in treating urticaria and as a possible adjunct treatment in children with atopic dermatitis.
Common Dosages
- Tablets: 10 mg.
- Chewable Tablets: 4 mg and 5 mg.
- Granules: 4 mg.
Typical Dosing
- For asthma: The usual dose for adults and children over 15 years is 10 mg once daily in the evening. For children aged 6 to 14 years, the recommended dose is 5 mg once daily, and for children aged 2 to 5 years, it is 4 mg once daily.
- For allergic rhinitis: The dosing is similar to asthma management.
Typical Dosing
FDA Approved Indications
- Asthma: for the prevention and long-term treatment of asthma in adults and children.
- Allergic Rhinitis: for the relief of seasonal allergic rhinitis symptoms in adults and children.
- Exercise-Induced Bronchoconstriction: for the prevention of exercise-induced bronchoconstriction in adults and children.
Pediatric Dosing
- Pediatric dosing for children will depend on what condition it's being used for, the age, and weight of the child. The doctor will provide specific instructions.
- Obesity might impact the effectiveness of the treatment so maintaining a healthy weight is crucial.
- Mood changes or unusual behavior are possible side effects, so keep an eye out and report any uncommon behaviors observed.
Who Shouldn't Take Montelukast Sodium?
- Known hypersensitivity to montelukast or any component of the formulation.
Advice From The Pharmacist
- Take montelukast exactly as prescribed, usually in the evening for optimal efficacy in asthma control.
- It can be taken with or without food. If using chewable tablets or granules, they can be taken directly or mixed with a spoonful of applesauce or similar soft food.
- Continue taking montelukast even if symptoms improve, as it is used for long-term management.
Side Effects of Montelukast Sodium
Common Side Effects
- Headache
- Dizziness
- Fatigue
- Abdominal pain
- Diarrhea
Uncommon/Severe Side Effects
- Mood changes (e.g., anxiety, depression)
- Allergic reactions (rash, itching, swelling)
- Changes in behavior or thoughts.
Risks and Warnings of Montelukast Sodium
- Neuropsychiatric Events: There have been reports of mood changes, aggression, anxiety, and depression; patients should be monitored for these effects, especially in children and adolescents.
- Not for Acute Asthma Attacks: Montelukast is not a rescue medication and should not be used for the treatment of acute asthma attacks.
Interactions with Montelukast Sodium
Common Drug Interactions
- Other Medications: Montelukast is generally well-tolerated with other medications, but it’s important to inform your healthcare provider about all medications you are taking, including over-the-counter drugs.
Common Food Interactions
Alternatives to Montelukast Sodium
- Inhaled Corticosteroids: Such as fluticasone or budesonide for asthma management.
- Other Leukotriene Modifiers: Such as zafirlukast, if a different option is needed.
