Browse Medications by Drug Class: Factor Xa Inhibitors

Written by Amar Lunagaria
Pharm.D • NiHowdy Founder

Reviewed by James Wong
Pharm.D • NiHowdy Founder
Published Jan 15, 2025

What are Factor Xa Inhibitors?
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List of drugs in Factor Xa Inhibitors
Drug Name | More Information | NiHowdy Prices & Bitcoin Rebate |
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Arixtra | Arixtra Information | Arixtra Pricing |
Eliquis | Eliquis Information | Eliquis Pricing |
Eliquis DVT/PE Starter Pack | Eliquis DVT/PE Starter Pack Information | Eliquis DVT/PE Starter Pack Pricing |
Fondaparinux Sodium | Fondaparinux Sodium Information | Fondaparinux Sodium Pricing |
Savaysa | Savaysa Information | Savaysa Pricing |
Xarelto | Xarelto Information | Xarelto Pricing |
Xarelto Starter Pack | Xarelto Starter Pack Information | Xarelto Starter Pack Pricing |
Brief history about Factor Xa Inhibitors?
How do Factor Xa Inhibitors work?
What are Factor Xa Inhibitors used to treat?
Atrial Fibrillation (AFib)
Factor Xa inhibitors are widely used in patients with non-valvular atrial fibrillation to prevent stroke and systemic embolism. By reducing clot formation in the heart, these medications lower the risk of clots traveling to the brain and causing a stroke. Unlike warfarin, Factor Xa inhibitors provide effective anticoagulation without the need for frequent INR monitoring.
Deep Vein Thrombosis (DVT)
Factor Xa inhibitors are effective in treating and preventing DVT, a condition where blood clots form in deep veins, usually in the legs. These medications reduce the risk of clot growth and prevent new clots from forming, alleviating symptoms like swelling and pain while preventing potentially life-threatening complications such as pulmonary embolism.
Pulmonary Embolism (PE)
For patients with pulmonary embolism, Factor Xa inhibitors are a first-line treatment to dissolve clots and prevent recurrence. By inhibiting clot formation, these medications restore blood flow to the lungs, improving oxygenation and reducing strain on the heart.
Who should consider Factor Xa Inhibitors medications?
Adults
Adults with conditions such as atrial fibrillation, deep vein thrombosis, or pulmonary embolism benefit significantly from Factor Xa inhibitors. These medications provide effective anticoagulation while minimizing the need for frequent monitoring. They are also used in adults undergoing major surgeries to prevent clot formation.
Children
While Factor Xa inhibitors are less commonly used in pediatric populations, they may be prescribed for children with clotting disorders or those undergoing specific medical treatments that increase thrombotic risk. Pediatric dosing is carefully adjusted based on weight and clinical condition, with close monitoring to ensure safety and efficacy.
Seniors
Seniors with atrial fibrillation, venous thromboembolism, or other clotting disorders often rely on Factor Xa inhibitors due to their predictable anticoagulant effects and convenience compared to older therapies. Age-related changes in kidney function and other comorbidities necessitate careful monitoring to balance the benefits of clot prevention with the risk of bleeding.
Are Factor Xa Inhibitors safe?
Can I take Factor Xa Inhibitors during pregnancy?
Are Factor Xa Inhibitors safe to take while lactating?
Are Factor Xa Inhibitors controlled substances?
Side effects of Factor Xa Inhibitors?
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