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Zilxi
Zilxi (generic name: minocycline topical foam) is a topical antibiotic used to treat the inflammatory lesions of rosacea. It is specifically designed as a foam formulation for easier application to affected areas, reducing the appearance of pimples and bumps associated with rosacea. Minocycline, the active ingredient in Zilxi, is part of the tetracycline class of antibiotics, which help reduce inflammation and bacterial growth in the skin.
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Frequently Asked Questions
How long does it take for Zilxi to work?
It may take 4 to 6 weeks of consistent use to notice significant improvements in rosacea symptoms. Continue using the medication as directed by your healthcare provider.
Can Zilxi be used on other areas of the body?
Zilxi is specifically formulated for use on the face. Consult your healthcare provider if you wish to use it on other areas affected by rosacea or similar conditions.
What should I do if I miss a dose of Zilxi?
If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.
Is Zilxi safe for long-term use?
Yes, Zilxi can be used long-term for the management of rosacea, but you should always follow your healthcare provider’s guidance and report any side effects or concerns during treatment.
Can I wear makeup while using Zilxi?
Yes, you can apply makeup over Zilxi, but make sure the foam has fully absorbed into the skin before applying cosmetics. Always use non-comedogenic (non-pore clogging) makeup to avoid worsening rosacea symptoms.
Comprehensive Drug Guide
How Does Zilxi Work?
Minocycline, the active ingredient in Zilxi, works by inhibiting protein synthesis in bacteria, which helps reduce bacterial growth. Although rosacea is not primarily caused by bacteria, the anti-inflammatory properties of minocycline help reduce the redness, swelling, and acne-like lesions associated with the condition.
Common Dosages
- 1.5% minocycline topical foam
Typical Dosing
- The typical dosing of Zilxi is once daily, applying a thin layer of foam to the affected areas of the face.
Typical Dosing
FDA Approved Indications
- Treatment of inflammatory lesions of rosacea in adults.
Who Shouldn't Take Zilxi?
- Known hypersensitivity to minocycline, tetracyclines, or any components of the formulation.
- Pregnancy: Minocycline, like other tetracyclines, can cause harm to an unborn baby (e.g., permanent tooth discoloration).
Advice From The Pharmacist
- Shake the can well before each use and apply a small amount of foam to clean, dry skin.
- Avoid contact with the eyes, mouth, and mucous membranes. If Zilxi comes into contact with these areas, rinse thoroughly with water.
- It may take several weeks to see the full benefits of Zilxi, so continue using it as directed even if your symptoms improve earlier.
- Use sunscreen daily, as tetracyclines can increase skin sensitivity to sunlight.
Side Effects of Zilxi
Common Side Effects
- Skin irritation (redness, dryness, itching)
- Temporary stinging or burning at the application site
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Photosensitivity (increased sensitivity to sunlight)
Risks and Warnings of Zilxi
- Photosensitivity: Minocycline can increase your skin’s sensitivity to sunlight. Avoid excessive sun exposure and wear sunscreen while using Zilxi to prevent sunburn.
- Allergic Reactions: Discontinue use and seek medical attention if you experience signs of an allergic reaction, such as rash, swelling, or difficulty breathing.
- Pregnancy and Breastfeeding: Zilxi should not be used during pregnancy, as it may cause harm to the unborn baby, including permanent tooth discoloration. Consult your healthcare provider if you are pregnant or breastfeeding.
Interactions with Zilxi
Common Drug Interactions
- Other topical medications: Using other topical treatments on the same areas as Zilxi may increase the risk of skin irritation. Consult your healthcare provider before combining treatments.
- Photosensitizing agents: Caution should be used when combining Zilxi with other medications that increase sensitivity to sunlight.
Alternatives to Zilxi
- Metronidazole gel (Metrogel): A common topical treatment for rosacea that helps reduce inflammation and redness.
- Azelaic acid (Finacea): Another topical treatment used to reduce rosacea symptoms and control redness.
- Ivermectin cream (Soolantra): An alternative topical treatment for the inflammatory lesions of rosacea.
