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Metrogel
Metrogel (generic name: metronidazole) is a topical antibiotic gel used primarily to treat rosacea, a chronic skin condition that causes redness, pimples, and visible blood vessels on the face. It is also used for the treatment of inflammatory lesions and pustules associated with rosacea. Metrogel works by reducing inflammation and targeting the bacteria that may contribute to rosacea symptoms. It is not a cure for rosacea but helps to manage and reduce flare-ups and symptoms over time.
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Frequently Asked Questions
How long does it take for Metrogel to work?
It may take 3 to 6 weeks of regular use to start seeing improvements in rosacea symptoms. Continue using Metrogel as directed by your healthcare provider.
Can Metrogel cure rosacea?
No, Metrogel does not cure rosacea. It helps manage the symptoms, including reducing redness, inflammation, and pustules, but the condition may flare up periodically.
Can I wear makeup while using Metrogel?
Yes, you can apply makeup after allowing Metrogel to fully absorb into the skin. Wait for about 5 to 10 minutes after applying the gel before applying makeup or other skincare products.
Can I use Metrogel if I have sensitive skin?
If you have sensitive skin, you may experience mild irritation or dryness when first using Metrogel. Start with a small amount, and if irritation persists or worsens, consult your healthcare provider.
Should I avoid the sun while using Metrogel?
Yes, it is recommended to use sunscreen and avoid prolonged sun exposure, as Metrogel may increase your skin's sensitivity to sunlight, potentially causing sunburn.
Comprehensive Drug Guide
How Does Metrogel Work?
Metrogel works by inhibiting the growth of certain bacteria and protozoa on the skin and reducing inflammation. Although the exact mechanism in treating rosacea is not fully understood, metronidazole has anti-inflammatory properties that help reduce the redness and swelling associated with rosacea. The antibacterial action of Metrogel helps minimize pustules and lesions by preventing bacterial growth on the skin.
Common Dosages
- 0.75% gel: Applied twice daily (morning and evening).
- 1% gel: Applied once daily.
Typical Dosing
- For rosacea:
- 0.75% gel: Apply a thin layer of Metrogel to the affected areas of the face twice daily (morning and evening).
- 1% gel: Apply a thin layer of Metrogel to the affected areas once daily.
- Always apply the medication to clean, dry skin, and allow it to absorb fully before applying makeup or other skincare products.
Typical Dosing
FDA Approved Indications
- Topical treatment of inflammatory papules and pustules of rosacea.
Who Shouldn't Take Metrogel?
- Known hypersensitivity to metronidazole or any component of the formulation.
- Use in patients with blood disorders (e.g., low blood cell counts) should be done with caution, as metronidazole may exacerbate these conditions.
Advice From The Pharmacist
- Apply Metrogel exactly as prescribed by your doctor. Be sure to wash and dry your face before applying a thin layer of the gel to the affected areas.
- Avoid getting Metrogel in your eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with water.
- It may take several weeks of consistent use to notice an improvement in rosacea symptoms. Continue using the medication even if you don’t see immediate results.
- If irritation, dryness, or worsening symptoms occur, stop using the product and consult your doctor.
- Metrogel should be stored at room temperature away from moisture and heat.
Side Effects of Metrogel
Common Side Effects
- Mild dryness or irritation at the application site
- Redness or burning sensation after application
- Watery eyes if applied too close to the eyes
Uncommon/Severe Side Effects
- Severe skin irritation or allergic reactions (rash, itching, swelling, difficulty breathing)
- Numbness or tingling in the hands or feet (neuropathy)
Risks and Warnings of Metrogel
- Irritation and Sensitivity: Some users may experience skin irritation, burning, or stinging upon application. If these symptoms persist or worsen, contact your healthcare provider.
- Eye Contact: Metrogel should not be applied near the eyes, as it can cause irritation and discomfort. If it accidentally gets into your eyes, rinse immediately with water.
- Sun Sensitivity: Metrogel may make your skin more sensitive to the sun. Use sunscreen and wear protective clothing when exposed to sunlight to prevent sunburn.
- Prolonged Use: Long-term use of Metrogel is generally safe, but it should be evaluated by your healthcare provider regularly to ensure it remains effective and safe.
Interactions with Metrogel
Common Drug Interactions
- Topical products: Using Metrogel alongside other topical medications, including retinoids or benzoyl peroxide, may increase the risk of skin irritation. Consult your doctor before combining treatments.
- Alcohol: Metronidazole, when taken orally, has been associated with a disulfiram-like reaction (nausea, vomiting, flushing) when combined with alcohol. Although this reaction is less common with topical use, it is still advised to avoid alcohol consumption during treatment.
Alternatives to Metrogel
- Finacea (azelaic acid): A topical treatment for rosacea that reduces inflammation and decreases the number of pimples.
- Soolantra (ivermectin): A topical cream used to treat rosacea, specifically targeting inflammatory lesions.
- Mirvaso (brimonidine): A topical gel used to reduce redness associated with rosacea by constricting blood vessels in the skin.
- Rhofade (oxymetazoline): A topical treatment used to reduce persistent facial redness in rosacea.
