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Tri-VyLibra Lo

Tri-VyLibra Lo is a combination oral contraceptive pill used to prevent pregnancy. It contains two hormones: ethinyl estradiol (a low dose of estrogen) and norgestimate (a progestin). These hormones work together to prevent ovulation, alter the lining of the uterus, and thicken cervical mucus, making it more difficult for sperm to reach the egg and for a fertilized egg to implant. Tri-VyLibra Lo follows a triphasic dosing schedule, which means it provides different hormone levels during three distinct phases of the menstrual cycle, closely mimicking natural hormone changes.



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Frequently Asked Questions

Can Tri-VyLibra Lo help with acne?
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Yes, Tri-VyLibra Lo is FDA-approved for the treatment of moderate acne in females aged 15 and older who desire oral contraception.

What should I do if I miss a pill?
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If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more active pills, refer to the instructions that come with your medication or contact your healthcare provider for guidance.

Can Tri-VyLibra Lo cause weight gain?
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Some women may experience slight weight gain due to fluid retention or other hormonal changes, but significant weight changes are uncommon.

Can I stop taking Tri-VyLibra Lo whenever I want?
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Yes, you can stop taking Tri-VyLibra Lo at any time. However, if you stop taking it and do not use another form of contraception, you will be at risk for pregnancy. Consult your healthcare provider for guidance on alternative contraception options.

Does Tri-VyLibra Lo protect against sexually transmitted infections (STIs)?
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No, Tri-VyLibra Lo does not protect against STIs. Condoms should be used to reduce the risk of STIs in addition to oral contraceptives.

Comprehensive Drug Guide

How Does Tri-VyLibra Lo Work?

  • Inhibiting ovulation: Prevents the release of an egg from the ovaries.
  • Thickening cervical mucus: Makes it difficult for sperm to travel to the uterus.
  • Altering the uterine l


Common Dosages

  • 21 active tablets with varying doses of ethinyl estradiol (a low dose) and norgestimate.
  • 7 inactive tablets (placebo), taken during the last week of the cycle.

Typical Dosing

  • Take one active pill daily for 21 days, followed by one inactive pill daily for 7 days.
  • Begin a new pack immediately after finishing the 28-day cycle, regardless of whether menstruation has started or ended.


Typical Dosing

FDA Approved Indications

  • Contraception (prevention of pregnancy)
  • Treatment of moderate acne in females at least 15 years old who desire oral contraception and have started menstruation


Who Shouldn't Take Tri-VyLibra Lo?

  • History of blood clots, stroke, or heart attack
  • Uncontrolled hypertension
  • Known or suspected breast cancer or other estrogen- or progestin-sensitive cancers
  • Liver disease
  • Pregnancy


Advice From The Pharmacist

  • Take Tri-VyLibra Lo at the same time every day to maintain consistent hormone levels and ensure maximum contraceptive effectiveness.
  • If you miss a pill, follow the instructions provided with your pack or consult your healthcare provider for guidance.
  • Tri-VyLibra Lo does not protect against sexually transmitted infections (STIs); using condoms is recommended for STI prevention.
  • Store the pills at room temperature, away from moisture and heat, and ensure you begin each new pack on time to maintain contraceptive coverage.


Side Effects of Tri-VyLibra Lo

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight changes
  • Mood swings


Uncommon/Severe Side Effects

  • Blood clots
  • Stroke or heart attack
  • High blood pressure
  • Liver issues


Risks and Warnings of Tri-VyLibra Lo

  • Blood Clot Risk: Women over 35 who smoke are at an increased risk of developing blood clots while using Tri-VyLibra Lo. It is strongly recommended to stop smoking if using this contraceptive.
  • Hypertension: Tri-VyLibra Lo may cause or worsen high blood pressure. Regular monitoring of blood pressure is recommended while taking this medication.
  • Cancer Risk: Prolonged use of combination oral contraceptives may increase the risk of breast cancer or liver tumors in some women.


Interactions with Tri-VyLibra Lo

Common Drug Interactions

  • Antibiotics: Certain antibiotics, such as rifampin, may reduce the effectiveness of Tri-VyLibra Lo.
  • Anticonvulsants: Some anticonvulsants can interfere with how Tri-VyLibra Lo works, potentially reducing its contraceptive effectiveness.
  • St. John's Wort: This herbal supplement may decrease the effectiveness of hormonal contraceptives.
  • HIV medications: Certain HIV treatments may interact with Tri-VyLibra Lo, making it less effective.


Alternatives to Tri-VyLibra Lo

  • Ortho Tri-Cyclen Lo: A similar combination oral contraceptive with the same active ingredients as Tri-VyLibra Lo.
  • Lo Loestrin Fe: A low-dose combination oral contraceptive option.
  • Depo-Provera: A progestin-only injectable contraceptive given every three months.
  • Intrauterine Device (IUD): A long-acting contraceptive option available in both hormonal and non-hormonal forms.