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VyLibra
VyLibra is an oral contraceptive containing levonorgestrel and ethinyl estradiol, used to prevent pregnancy. It works by inhibiting ovulation (the release of an egg), thickening cervical mucus to prevent sperm from reaching the egg, and altering the uterine lining to prevent implantation of a fertilized egg. VyLibra is also used to regulate menstrual cycles, treat acne, and reduce the risk of ovarian cysts.
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Frequently Asked Questions
How effective is VyLibra at preventing pregnancy?
VyLibra is over 99% effective at preventing pregnancy when taken as directed. However, missing doses or taking pills inconsistently may reduce its effectiveness.
What should I do if I miss a dose of VyLibra?
If you miss one active pill, take it as soon as you remember. If you miss two or more pills, follow the instructions in the package insert and use backup contraception for the next 7 days.
Can VyLibra cause weight gain?
Weight gain is a possible side effect, although it is generally mild. Weight changes may result from fluid retention or hormonal fluctuations.
Is it safe to take VyLibra if I smoke?
Smoking increases the risk of serious cardiovascular side effects, especially in women over 35. It is not recommended to smoke while using VyLibra or other hormonal contraceptives.
Can I use VyLibra to treat acne?
Yes, VyLibra may help reduce acne in women seeking hormonal contraception. It regulates hormone levels, which can improve skin clarity over time.
Comprehensive Drug Guide
How Does VyLibra Work?
VyLibra works by preventing ovulation and altering the cervical mucus and uterine lining. Levonorgestrel is a synthetic progestin that suppresses the release of luteinizing hormone (LH), which is necessary for ovulation, while ethinyl estradiol suppresses the release of follicle-stimulating hormone (FSH), further preventing egg release. Together, these hormones also thicken the cervical mucus and thin the uterine lining, making it less likely for sperm to reach the egg or for a fertilized egg to implant.
Common Dosages
- 21 active tablets containing 0.15 mg levonorgestrel and 0.03 mg ethinyl estradiol
- 7 placebo tablets for a hormone-free week.
Typical Dosing
- Take one active pill daily for 21 days, followed by one placebo pill daily for 7 days. During the placebo week, withdrawal bleeding typically occurs, mimicking a natural menstrual cycle.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy
- Menstrual cycle regulation
- Reduction of acne in women seeking contraception
- Management of hormonal imbalances and symptoms like heavy or painful periods
Who Shouldn't Take VyLibra?
- A history of blood clots, stroke, or heart attack
- Known or suspected breast cancer or other hormone-sensitive cancers
- Uncontrolled hypertension
- Liver disease or liver tumors
- Known hypersensitivity to levonorgestrel, ethinyl estradiol, or any inactive ingredients in VyLibra
Advice From The Pharmacist
- Take VyLibra at the same time every day to ensure its effectiveness. Missing pills or taking them inconsistently increases the risk of pregnancy.
- If you miss one pill, take it as soon as you remember. If you miss two or more pills, follow the package instructions and use backup contraception for the next 7 days.
- VyLibra does not protect against sexually transmitted infections (STIs), so additional protection, such as condoms, should be used to prevent STIs.
- Some medications, including antibiotics and anticonvulsants, may reduce the effectiveness of VyLibra, so inform your healthcare provider about any other medications you are taking.
Side Effects of VyLibra
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Weight changes
- Mood swings
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke or heart attack
- High blood pressure
- Liver problems (jaundice, elevated liver enzymes)
Risks and Warnings of VyLibra
- Cardiovascular Risk: Smoking while using VyLibra, especially in women over 35, increases the risk of serious cardiovascular events such as heart attack, stroke, or blood clots.
- Blood Clots: Combination oral contraceptives like VyLibra may increase the risk of blood clots, particularly in women with a history of clotting disorders, obesity, or smoking.
- Breast Cancer: There is a slightly increased risk of developing breast cancer in women using hormonal contraceptives, especially those with a family history of breast cancer.
Interactions with VyLibra
Common Drug Interactions
- Antibiotics: Some antibiotics, particularly rifampin, may reduce the effectiveness of VyLibra. Use backup contraception while taking antibiotics.
- Anticonvulsants: Medications used to treat seizures may interfere with the contraceptive efficacy of VyLibra.
- St. John’s Wort: This herbal supplement may decrease the effectiveness of VyLibra by increasing the breakdown of hormones in the liver.
Alternatives to VyLibra
- Alesse (levonorgestrel/ethinyl estradiol): A similar combination oral contraceptive with the same active ingredients.
- Ortho Tri-Cyclen (norgestimate/ethinyl estradiol): A combination oral contraceptive often used to treat acne in women seeking contraception.
- Depo-Provera (medroxyprogesterone acetate): A long-acting injectable contraceptive.
- Mirena (levonorgestrel): An intrauterine device (IUD) that provides long-term contraception.
