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Tri-VyLibra
Tri-VyLibra is a combination oral contraceptive pill used to prevent pregnancy. It contains two active ingredients: ethinyl estradiol (an estrogen) and norgestimate (a progestin). These hormones work together to prevent ovulation, alter the uterine lining, and thicken cervical mucus, making it harder for sperm to reach the egg and for a fertilized egg to implant. Tri-VyLibra follows a triphasic dosing schedule, providing different hormone levels at various points in the menstrual cycle to better mimic the body’s natural hormone fluctuations.
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Frequently Asked Questions
Can Tri-VyLibra help with acne?
Yes, Tri-VyLibra is FDA-approved for the treatment of moderate acne in females 15 years and older who desire oral contraception.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more active pills, refer to the instructions that come with your medication or contact your healthcare provider for guidance.
Can I use Tri-VyLibra if I have a history of migraines?
If you have migraines, particularly those with aura, discuss this with your healthcare provider, as combination oral contraceptives may increase the risk of stroke in women with certain types of migraines.
Does Tri-VyLibra cause weight gain?
Some women may experience slight weight gain due to fluid retention or other hormonal changes while using Tri-VyLibra, but significant weight gain is uncommon.
Can I stop taking Tri-VyLibra whenever I want?
Yes, you can stop taking Tri-VyLibra at any time. However, if you stop taking it and do not switch to another form of contraception, you will be at risk for pregnancy. Consult your healthcare provider for guidance on alternative contraception options if you decide to stop.
Comprehensive Drug Guide
How Does Tri-VyLibra Work?
- Inhibiting ovulation: Preventing the release of an egg from the ovaries.
- Thickening cervical mucus: Making it harder for sperm to reach the uterus.
- Altering the uterine lining: Reducing the likelihood of implantation of a fertilized egg.
Common Dosages
- 21 active tablets: with varying doses of ethinyl estradiol and norgestimate.
- 7 inactive tablets: placebo pills to be taken during the last week of the cycle.
Typical Dosing
- Take one active pill daily for 21 days, followed by one inactive pill daily for 7 days.
- After completing the 28-day cycle, start a new pack immediately, regardless of whether menstruation has started or ended.
Typical Dosing
FDA Approved Indications
- Contraception (prevention of pregnancy)
- Treatment of moderate acne in females 15 years and older who desire oral contraceptive therapy
Who Shouldn't Take Tri-VyLibra?
- A history of blood clots, stroke, or heart attack
- Uncontrolled hypertension
- Known or suspected breast cancer or other estrogen- or progestin-sensitive cancers
- Liver disease
- Pregnancy
Advice From The Pharmacist
- Take Tri-VyLibra at the same time every day to maintain consistent hormone levels and ensure maximum effectiveness.
- If you miss a pill, follow the instructions provided with your pack to determine whether you need backup contraception.
- Tri-VyLibra does not protect against sexually transmitted infections (STIs); using condoms is recommended for STI prevention.
- Store your pills at room temperature, away from moisture and heat, and ensure you start each new pack on time.
Side Effects of Tri-VyLibra
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Weight gain
- Mood changes
Uncommon/Severe Side Effects
- Blood clots
- Stroke or heart attack
- High blood pressure
- Liver problems
Risks and Warnings of Tri-VyLibra
- Blood Clot Risk: Women who smoke and are over 35 years old are at an increased risk of developing blood clots while using Tri-VyLibra. It is strongly recommended to stop smoking if using this contraceptive.
- Hypertension: Tri-VyLibra can cause or worsen high blood pressure. Your doctor may monitor your blood pressure while on this medication.
- Cancer Risk: Prolonged use of combination contraceptives may increase the risk of breast cancer or liver tumors in some women.
Interactions with Tri-VyLibra
Common Drug Interactions
- Antibiotics: Certain antibiotics, such as rifampin, may reduce the effectiveness of Tri-VyLibra.
- Anticonvulsants: Some anticonvulsants can interfere with how Tri-VyLibra works, potentially reducing its contraceptive effectiveness.
- St. John's Wort: This herbal supplement may decrease the effectiveness of hormonal contraceptives.
- HIV Medications: Certain HIV treatments may interact with hormonal contraceptives, making them less effective.
Alternatives to Tri-VyLibra
- Ortho Tri-Cyclen: A similar combination oral contraceptive with the same active ingredients as Tri-VyLibra.
- Lo Loestrin Fe: A low-dose estrogen and progestin contraceptive pill.
- Depo-Provera: A progestin-only injectable contraceptive given every three months.
- Intrauterine Device (IUD): A long-acting contraceptive option available in both hormonal and non-hormonal forms.
