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Topicort
Topicort (generic name: desoximetasone) is a topical corticosteroid used to treat a variety of skin conditions such as eczema, psoriasis, and dermatitis. It works by reducing inflammation, redness, and itching associated with these conditions. Desoximetasone is a potent corticosteroid and is often prescribed for moderate to severe inflammatory skin conditions that do not respond to milder treatments.
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Frequently Asked Questions
How long does it take for Topicort to start working?
You may notice improvement in symptoms within a few days of starting treatment, but it may take up to two weeks to see significant relief.
Can Topicort be used on the face?
While Topicort is effective for treating skin conditions, it should be used with caution on the face due to the risk of skin thinning. Consult your healthcare provider before using it on sensitive areas like the face.
What should I do if I miss a dose of Topicort?
If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra medication to make up for the missed dose.
Can Topicort be used long-term?
Topicort should be used for the shortest duration possible to manage your symptoms. Long-term use increases the risk of side effects such as skin thinning and adrenal suppression.
Is it safe to use Topicort in children?
Topicort can be used in children, but only under the guidance of a healthcare provider. Children may be more susceptible to side effects, so close monitoring is essential.
Comprehensive Drug Guide
How Does Topicort Work?
Topicort works by inhibiting the release of substances in the skin that cause inflammation and allergic reactions. As a corticosteroid, it reduces immune system activity in the skin, thereby decreasing swelling, redness, and itching. This leads to relief from the symptoms associated with skin conditions like eczema and psoriasis.
Common Dosages
- 0.25% cream, ointment, and gel
- 0.05% cream, ointment, and gel
Typical Dosing
- For inflammatory skin conditions: Apply a thin layer of Topicort to the affected area(s) twice daily. The dosage and duration may vary depending on the severity of the condition and the patient’s response to treatment. Use should be limited to the smallest effective amount for the shortest duration.
Typical Dosing
FDA Approved Indications
- Inflammatory and pruritic (itchy) manifestations of corticosteroid-responsive dermatoses, such as:
- Psoriasis
- Atopic dermatitis
- Contact dermatitis
- Seborrheic dermatitis
Who Shouldn't Take Topicort?
- Known hypersensitivity to desoximetasone or any of the other components of the formulation
- Untreated skin infections (e.g., bacterial, viral, or fungal infections)
Advice From The Pharmacist
- Apply Topicort only to the affected areas as directed by your healthcare provider. Avoid contact with the eyes, mouth, or open wounds.
- Do not cover the treated area with a bandage or occlusive dressing unless instructed by your doctor, as this can increase absorption and lead to more side effects.
- Wash your hands before and after application unless you are treating your hands.
- Use Topicort for the shortest duration necessary, as long-term use can increase the risk of skin thinning and other side effects.
Side Effects of Topicort
Common Side Effects
- Skin irritation (burning, itching, or redness)
- Dryness or cracking of the skin
- Acne-like eruptions
- Thinning of the skin (with prolonged use)
Uncommon/Severe Side Effects
- Skin infections (due to immune suppression)
- Stretch marks (striae)
- Adrenal suppression (with excessive use)
- Allergic contact dermatitis
Risks and Warnings of Topicort
- Skin Thinning: Prolonged use of Topicort, especially on sensitive areas such as the face or underarms, can cause thinning of the skin. Limit use to the prescribed duration.
- Systemic Absorption: Although rare, prolonged use of high-potency corticosteroids like Topicort can lead to systemic absorption, potentially causing symptoms like weight gain, fatigue, or mood changes.
- Infection Risk: Topical corticosteroids can mask the symptoms of skin infections, making it harder to treat them properly.
Interactions with Topicort
Common Drug Interactions
- Other topical corticosteroids: Using multiple corticosteroid products can increase the risk of side effects like skin thinning or adrenal suppression.
- Occlusive dressings: Covering the treated area with occlusive dressings can enhance the absorption of desoximetasone, increasing the risk of systemic side effects.
Alternatives to Topicort
- Hydrocortisone: A milder topical corticosteroid often used for less severe inflammatory skin conditions.
- Triamcinolone acetonide: Another potent corticosteroid used for treating inflammatory skin conditions.
- Calcipotriene (Dovonex): A non-steroidal topical treatment for psoriasis.
- Tacrolimus (Protopic): A non-corticosteroid topical immunosuppressant used for treating eczema.
