Tekturna

• Hypertension (high blood pressure), either alone or in combination with other antihypertensive agents

It is used to reduce blood pressure and decrease the risk of complications associated with hypertension, such as heart attacks and strokes.

• Known hypersensitivity to aliskiren or any component of the formulation
• Pregnancy, as Tekturna can cause injury or death to the developing fetus
• Concomitant use with ACE inhibitors or ARBs in patients with diabetes due to the increased risk of kidney problems, hyperkalemia, and low blood pressure

• Take Tekturna at the same time each day to maintain steady levels in your body. Avoid high-fat meals, as they can interfere with the absorption of the medication.
• Do not stop taking Tekturna abruptly, as this may cause a rebound increase in blood pressure. Consult your doctor if you need to discontinue or adjust your treatment.
• Avoid taking Tekturna with ACE inhibitors or ARBs if you have diabetes or kidney problems, as this combination increases the risk of serious side effects.
• Regularly monitor your blood pressure and kidney function while taking Tekturna. Your doctor may also check your potassium levels, as this medication can increase the risk of hyperkalemia (high potassium levels).
• Store Tekturna at room temperature, away from moisture and heat.

• Diarrhea
• Dizziness
• Fatigue
• Cough

• Hyperkalemia (high potassium levels), which can cause muscle weakness, irregular heartbeats, or paralysis
• Kidney problems, such as decreased urine output or swelling in the legs and feet
• Severe allergic reactions, such as rash, swelling of the face, lips, or throat, and difficulty breathing
• Hypotension (low blood pressure), especially when starting the medication or increasing the dose

• Fetal Toxicity: Tekturna should not be used during pregnancy, as it can cause harm or death to the fetus. Women of childbearing age should use effective contraception while taking Tekturna. If pregnancy occurs, stop the medication immediately and consult your healthcare provider.
• Kidney Risk: Tekturna can worsen kidney function, especially in individuals with pre-existing kidney conditions. Monitoring of kidney function is important during treatment.
• Hyperkalemia: Tekturna can increase potassium levels, especially when used in combination with other drugs that raise potassium, such as potassium supplements, ACE inhibitors, or ARBs.

• ACE inhibitors or ARBs: Using Tekturna with ACE inhibitors or ARBs (e.g., lisinopril, losartan) in patients with diabetes or kidney problems can increase the risk of kidney dysfunction, hyperkalemia, and low blood pressure.
• Potassium supplements or potassium-sparing diuretics: Combining Tekturna with drugs that raise potassium levels (e.g., spironolactone) can lead to dangerous elevations in potassium.
• NSAIDs (e.g., ibuprofen): Prolonged use of NSAIDs with Tekturna can reduce the drug’s effectiveness and increase the risk of kidney damage, especially in patients with pre-existing kidney conditions.
• Cyclosporine or itraconazole: These medications can increase Tekturna levels in the body, raising the risk of side effects.

• ACE inhibitors (e.g., lisinopril): A commonly used class of drugs for hypertension that reduces blood pressure by inhibiting the conversion of angiotensin I to angiotensin II.
• ARBs (e.g., losartan): These medications block the action of angiotensin II, helping to relax blood vessels and lower blood pressure.
• Calcium channel blockers (e.g., amlodipine): These medications help relax and widen blood vessels to reduce blood pressure.
• Thiazide diuretics (e.g., hydrochlorothiazide): Commonly used to treat hypertension by promoting the removal of excess fluid and sodium from the body.