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Striverdi Respimat
Striverdi Respimat (generic name: olodaterol) is a long-acting beta-2 adrenergic agonist (LABA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It works by relaxing the muscles in the airways, helping to keep them open and making breathing easier. Striverdi Respimat is not a rescue inhaler and should not be used to treat sudden breathing problems.
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Frequently Asked Questions
How quickly does Striverdi Respimat start working?
Striverdi Respimat typically starts working within 5 to 15 minutes of inhalation, but its effects last for 24 hours, so it only needs to be taken once daily.
Can Striverdi Respimat be used for asthma?
No, Striverdi Respimat is not approved for the treatment of asthma and should not be used in patients with asthma unless prescribed in combination with other asthma medications. LABAs carry an increased risk of asthma-related death if used alone without inhaled corticosteroids.
Can I stop taking Striverdi Respimat if I feel better?
No, Striverdi Respimat is a maintenance medication for COPD. It must be taken regularly, even if you feel better, to keep your symptoms under control. Stopping the medication may result in worsened breathing symptoms.
What should I do if I miss a dose of Striverdi Respimat?
If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once.
Can Striverdi Respimat be used in combination with other COPD medications?
Yes, Striverdi Respimat is often used in combination with other COPD medications, such as inhaled corticosteroids or anticholinergic bronchodilators, to provide better symptom control. Your doctor will determine the most appropriate combination for you.
Comprehensive Drug Guide
How Does Striverdi Respimat Work?
Olodaterol, the active ingredient in Striverdi Respimat, is a selective beta-2 adrenergic agonist that works by stimulating beta-2 receptors in the bronchial smooth muscles. This stimulation causes the muscles in the airways to relax, resulting in bronchodilation (widening of the airways) and making it easier to breathe. This effect lasts for 24 hours, allowing for once-daily dosing.
Common Dosages
- 2.5 mcg of olodaterol
Typical Dosing
- The recommended dose for adults is two inhalations once daily, taken at the same time each day.
- It is important to use the inhaler exactly as prescribed to maintain stable airway function and control COPD symptoms.
Typical Dosing
FDA Approved Indications
- The long-term, once-daily maintenance treatment of COPD, including chronic bronchitis and emphysema.
- It is not approved for treating asthma or acute episodes of bronchospasm.
Who Shouldn't Take Striverdi Respimat?
- Hypersensitivity to olodaterol or any components of the inhaler.
- Acute bronchospasm: Striverdi Respimat should not be used to treat sudden breathing problems or asthma attacks (a rescue inhaler, such as albuterol, is needed for acute symptoms).
- Patients with asthma who are not using a long-term asthma control medication, as LABAs used alone without a corticosteroid increase the risk of asthma-related death.
Advice From The Pharmacist
- Use Striverdi Respimat once daily at the same time every day, as part of your regular COPD management plan. Do not take extra doses.
- Striverdi Respimat is not a rescue inhaler and will not relieve sudden breathing problems. Always keep a short-acting beta agonist (such as albuterol) for emergency use.
- Ensure you receive proper training on how to use the Respimat inhaler. If the inhaler is not used correctly, you may not receive the full dose of medication.
Side Effects of Striverdi Respimat
Common Side Effects
- Cough
- Upper respiratory tract infections
- Dizziness
- Back pain
- Joint pain
Uncommon/Severe Side Effects
- Paradoxical bronchospasm: This is a rare but serious condition where inhaling the medication causes the airways to narrow instead of open.
- Cardiovascular effects: Increased heart rate, palpitations, and high blood pressure, especially in patients with pre-existing heart conditions.
- Hypokalemia: Low potassium levels, which can cause muscle weakness or cramps.
- Hyperglycemia: High blood sugar levels in some patients.
Risks and Warnings of Striverdi Respimat
- Asthma-Related Death: Long-acting beta-2 agonists (LABAs) like Striverdi Respimat should not be used as a monotherapy for asthma due to the increased risk of asthma-related death. It is approved only for COPD patients.
- Paradoxical Bronchospasm: Although rare, Striverdi Respimat can sometimes cause paradoxical bronchospasm, where the airways tighten instead of relaxing. If this happens, stop using the inhaler immediately and seek medical attention.
- Cardiovascular Effects: LABAs can cause heart-related side effects such as increased heart rate and blood pressure. Patients with cardiovascular diseases should use Striverdi with caution.
Interactions with Striverdi Respimat
Common Drug Interactions
- Beta-blockers: Drugs like propranolol may block the effects of Striverdi and worsen COPD symptoms. However, cardioselective beta-blockers can be used cautiously.
- Diuretics: Using diuretics (such as furosemide) with Striverdi Respimat can increase the risk of low potassium levels (hypokalemia), leading to muscle weakness and heart issues.
- Other bronchodilators: Using Striverdi Respimat with other long-acting beta agonists or medications with similar effects can increase the risk of side effects like tachycardia and palpitations.
Alternatives to Striverdi Respimat
- Spiriva Respimat (tiotropium): A long-acting anticholinergic used for the maintenance treatment of COPD.
- Breo Ellipta (fluticasone furoate/vilanterol): A combination of an inhaled corticosteroid and LABA, used for the treatment of COPD.
- Advair Diskus (fluticasone/salmeterol): A combination of an inhaled corticosteroid and LABA used for COPD and asthma (in specific cases).
- Symbicort (budesonide/formoterol): Another combination inhaler for COPD that includes an inhaled corticosteroid and a long-acting bronchodilator.
