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Spiriva Respimat

Spiriva Respimat (tiotropium bromide) is a long-acting anticholinergic bronchodilator used for the management of chronic obstructive pulmonary disease (COPD) and asthma. It works by relaxing the muscles in the airways, leading to improved airflow and easier breathing. Spiriva Respimat is designed for once-daily inhalation, providing 24-hour relief from respiratory symptoms.



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Frequently Asked Questions

How long does it take for Spiriva Respimat to start working?
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Spiriva typically begins to work within a few hours after inhalation, with maximum effects occurring over several days of consistent use.

Can I use Spiriva Respimat with other inhalers?
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Yes, Spiriva can be used alongside other inhaled medications, but consult your healthcare provider to ensure proper use and timing.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.

Is Spiriva Respimat safe for long-term use?
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Yes, Spiriva is designed for long-term use in managing COPD and asthma, but regular follow-up with your healthcare provider is important to monitor efficacy and safety.

Can I take Spiriva Respimat during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the potential risks and benefits of using Spiriva.

Comprehensive Drug Guide

How Does Spiriva Respimat Work?

Tiotropium bromide, the active ingredient in Spiriva, works by blocking the action of acetylcholine at muscarinic receptors in the airways. This inhibition leads to bronchodilation (widening of the airways), which helps alleviate symptoms of bronchospasm associated with COPD and asthma.



Common Dosages

  • Inhalation Spray: 2.5 mcg per actuation, with the typical dosing regimen being two actuations once daily.

Typical Dosing

  • For COPD: The usual dose is two actuations (5 mcg total) once daily.
  • For asthma: The dose may vary based on individual response and the specific treatment plan outlined by the healthcare provider.


Typical Dosing

FDA Approved Indications

  • Maintenance treatment of COPD
  • Maintenance treatment of asthma in patients aged 6 years and older


Who Shouldn't Take Spiriva Respimat?

  • Known hypersensitivity to tiotropium or any components of the formulation.
  • A history of severe allergic reactions to similar medications.


Advice From The Pharmacist

  • Use Spiriva Respimat exactly as prescribed. Do not exceed the recommended dose.
  • Ensure you are properly trained in the use of the inhaler for effective delivery of the medication.
  • Monitor your symptoms regularly and keep your healthcare provider informed of any changes, especially if you experience worsening breathing problems.
  • Avoid getting the medication in your eyes, as it may cause irritation.


Side Effects of Spiriva Respimat

Common Side Effects

  • Dry mouth
  • Cough
  • Headache
  • Bronchitis
  • Constipation

Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Worsening of breathing problems or acute bronchospasm


Risks and Warnings of Spiriva Respimat

  • Cardiovascular Effects: Caution is advised in patients with a history of cardiovascular disease, as anticholinergic medications can cause palpitations or increased heart rate.
  • Paradoxical Bronchospasm: In rare cases, Spiriva can cause worsening respiratory symptoms. If this occurs, seek medical attention immediately.


Interactions with Spiriva Respimat

Common Drug Interactions

  • Other Anticholinergic Medications: Use with caution when combining with other anticholinergic drugs, as this may increase the risk of side effects.
  • Beta-agonist Bronchodilators: Concurrent use is generally safe, but patients should be monitored for increased side effects.


Common Food Interactions


Alternatives to Spiriva Respimat

  • Other LAMAs: Such as umeclidinium (Incruse Ellipta) or glycopyrrolate (Seebri Neohaler) may be considered for similar indications.
  • Short-acting bronchodilators: Such as albuterol for acute symptom relief.