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Sprintec 28
Sprintec 28 is a combined oral contraceptive that contains two hormones: ethinyl estradiol (an estrogen) and norgestimate (a progestin). It is used to prevent pregnancy by inhibiting ovulation, thickening cervical mucus to prevent sperm from reaching the egg, and altering the uterine lining to prevent implantation. Sprintec 28 is also sometimes prescribed to treat conditions such as acne, irregular periods, and menstrual cramps.
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Frequently Asked Questions
How effective is Sprintec 28 at preventing pregnancy?
When taken correctly (at the same time every day), Sprintec 28 is over 99% effective at preventing pregnancy. However, with typical use (missed pills or inconsistent timing), the effectiveness drops to around 91%.
Can I skip my period by taking only the active pills?
Yes, if you want to skip your period, you can start a new pack of active pills immediately after finishing the active pills from your current pack, skipping the placebo pills.
What should I do if I miss a dose of Sprintec 28?
If you miss one active pill, take it as soon as you remember and continue taking the rest as scheduled. If you miss two or more active pills, follow the instructions in the package insert, and use a backup method of contraception (like condoms) for the next 7 days.
Can Sprintec 28 help with acne?
Yes, Sprintec 28 is sometimes prescribed to treat moderate acne in women who also want contraception. The hormones in the pill can reduce the production of androgens, which are linked to acne.
Does Sprintec 28 cause weight gain?
While some women report weight changes on hormonal birth control, studies have not consistently shown a direct link between birth control pills and significant weight gain. Maintaining a healthy lifestyle can help manage weight while on Sprintec 28.
Comprehensive Drug Guide
How Does Sprintec 28 Work?
- Prevention of ovulation: The hormones in Sprintec 28 prevent the release of an egg from the ovaries each month.
- Thickening of cervical mucus: The cervical mucus is thickened, making it difficult for sperm to reach the egg.
- Changes in the uterine lining: The lining of the uterus is altered to make it less suitable for a fertilized egg to implant.
What is Sprintec 28 Used For?
Common Dosages
- 21 active tablets, each with 0.035 mg of ethinyl estradiol and 0.25 mg of norgestimate.
- 7 inactive placebo tablets.
Typical Dosing
- One active tablet is taken daily for 21 days, followed by one placebo tablet daily for 7 days. After completing the 28-day cycle, a new pack is started the next day.
- The pills should be taken at the same time every day to maintain consistent hormone levels and maximize contraceptive effectiveness.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy (contraception)
- Treatment of moderate acne in women at least 15 years of age, who have started menstruating and desire contraception.
- Regulation of menstrual cycles and reduction of menstrual pain.
Who Shouldn't Take Sprintec 28?
- History of thromboembolic disorders (e.g., deep vein thrombosis or pulmonary embolism)
- Hormone-related cancers, such as breast or uterine cancer
- Liver disease
- Uncontrolled hypertension
- Smokers over the age of 35, due to the increased risk of cardiovascular events
Advice From The Pharmacist
- Take Sprintec 28 at the same time every day, even if you are not sexually active at the moment. Consistency is key to maintaining its effectiveness.
- If you miss a dose, take it as soon as you remember. If you miss two or more doses, follow the instructions provided with the medication and consider using a backup method of contraception, such as condoms, for at least 7 days.
- Sprintec 28 does not protect against sexually transmitted infections (STIs). Use condoms to protect against STIs.
Side Effects of Sprintec 28
Common Side Effects
- Nausea or vomiting
- Breast tenderness
- Headache
- Changes in menstrual flow or spotting between periods
- Mood changes
Uncommon/Severe Side Effects
- Blood clots: Symptoms include leg pain or swelling, shortness of breath, or chest pain.
- Stroke or heart attack: Symptoms include sudden numbness or weakness, severe headache, or vision problems.
- Liver problems: Signs include jaundice (yellowing of the skin or eyes).
Risks and Warnings of Sprintec 28
- Risk of Blood Clots: Like other combined hormonal contraceptives, Sprintec 28 increases the risk of blood clots, especially in women who smoke, are over 35 years of age, or have other risk factors (e.g., obesity or history of clotting disorders).
- High Blood Pressure: Sprintec 28 may increase blood pressure, so regular monitoring is recommended, particularly in women with a history of hypertension.
- Cancer Risk: The use of hormonal contraceptives has been associated with a slight increase in the risk of breast and cervical cancer, but the risk is generally outweighed by the benefits of preventing ovarian and endometrial cancer.
Interactions with Sprintec 28
Common Drug Interactions
- Antibiotics and anticonvulsants: Certain medications, such as rifampin and carbamazepine, may decrease the effectiveness of Sprintec 28. A backup form of contraception may be needed during and after use of these medications.
- St. John’s Wort: This herbal supplement can reduce the effectiveness of Sprintec 28 by increasing the breakdown of its hormones in the liver.
- Antiretrovirals: Some medications used to treat HIV may interact with Sprintec 28, reducing its effectiveness.
Alternatives to Sprintec 28
- Ortho Tri-Cyclen: A similar combination oral contraceptive that varies hormone levels throughout the cycle to more closely mimic the natural menstrual cycle.
- Yaz (drospirenone and ethinyl estradiol): A combined oral contraceptive that contains a different type of progestin, with additional benefits for treating acne and premenstrual dysphoric disorder (PMDD).
- Depo-Provera (medroxyprogesterone): A long-acting injectable contraceptive that provides pregnancy protection for 3 months.
- IUD (intrauterine device): A long-term contraceptive device inserted into the uterus that can be hormone-based (e.g., Mirena) or non-hormonal (e.g., copper IUD).
