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Pediapred

Pediapred (generic name: prednisolone sodium phosphate) is an oral corticosteroid solution commonly prescribed for children to treat a variety of inflammatory and allergic conditions, including asthma, allergic reactions, rheumatoid arthritis, and immune system disorders. Prednisolone works by suppressing the immune system’s inflammatory response, providing relief from symptoms such as swelling, redness, and itching. Pediapred is typically used in cases where an immediate reduction in inflammation is required.



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Frequently Asked Questions

How long does it take for Pediapred to start working?
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Pediapred may begin to show improvements in symptoms within hours to a few days, depending on the condition being treated.

Can Pediapred be used long-term?
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While Pediapred can be used long-term for chronic conditions, close monitoring by a healthcare provider is necessary to manage potential side effects, especially in children.

What should I do if I miss a dose of Pediapred?
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If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose. Do not double up on doses.

Can Pediapred be taken with other medications?
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Always consult your healthcare provider about potential interactions. Certain medications, such as NSAIDs or diuretics, may interact with Pediapred and increase the risk of side effects.

Can Pediapred affect my child’s growth?
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Long-term use of corticosteroids like Pediapred may affect growth in children. Regular monitoring by a healthcare provider can help manage this risk.

Comprehensive Drug Guide

How Does Pediapred Work?

Pediapred works by suppressing the immune system and reducing the activity of chemicals in the body that cause inflammation. By inhibiting the release of inflammatory substances, prednisolone helps alleviate symptoms associated with various allergic and autoimmune conditions. This makes it effective in treating acute and chronic inflammatory diseases.



Typical Dosing

FDA Approved Indications

  • Asthma and other chronic respiratory diseases
  • Allergic reactions (e.g., severe skin reactions, hives)
  • Rheumatoid arthritis and other autoimmune disorders
  • Lupus
  • Inflammatory bowel disease
  • Severe allergies


Who Shouldn't Take Pediapred?

  • Systemic fungal infections
  • Known hypersensitivity to prednisolone or any of its components
  • Live vaccinations (as corticosteroids can suppress the immune response)


Advice From The Pharmacist

  • Administer Pediapred with food or milk to reduce stomach upset, which can be a side effect of corticosteroids.
  • Use the provided measuring device to ensure accurate dosing, especially for children.
  • Gradually taper off Pediapred if used for extended periods, as sudden discontinuation can cause withdrawal symptoms. Always follow the healthcare provider’s instructions for tapering.
  • If you miss a dose, take it as soon as you remember, unless it’s close to the next scheduled dose. Do not double up on doses.
  • Store Pediapred at room temperature and protect it from light.


Side Effects of Pediapred

Common Side Effects

  • Increased appetite
  • Weight gain
  • Stomach upset or nausea
  • Mood changes (e.g., irritability, restlessness)
  • Difficulty sleeping (insomnia)


Uncommon/Severe Side Effects

  • High blood pressure
  • Increased risk of infections
  • Bone loss (osteoporosis) with long-term use
  • Adrenal suppression if used for extended periods without tapering


Risks and Warnings of Pediapred

  • Suppression of the Immune System: Pediapred can suppress the immune system, making patients more susceptible to infections. If your child develops symptoms of an infection, contact a healthcare provider.
  • Growth Suppression: Long-term use of corticosteroids in children may affect growth. Regular monitoring by a healthcare provider is necessary to manage this risk.
  • Stomach Issues: Pediapred may increase the risk of gastric ulcers or bleeding, especially when taken with NSAIDs like ibuprofen. Always take it with food or milk to minimize gastrointestinal side effects.


Interactions with Pediapred

Common Drug Interactions

  • NSAIDs (e.g., ibuprofen, naproxen): May increase the risk of stomach ulcers or bleeding.
  • Diuretics: May increase the risk of low potassium levels.
  • Vaccines: Live vaccines should not be administered while taking corticosteroids due to the risk of infection.
  • Anticonvulsants (e.g., phenytoin, carbamazepine): May affect prednisolone levels.


Alternatives to Pediapred

  • Dexamethasone: A stronger corticosteroid used for similar conditions.
  • Prednisone: Another corticosteroid, available in tablet form for treating similar inflammatory and allergic conditions.
  • Hydrocortisone: A milder corticosteroid used in less severe cases or for shorter-term treatment.