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oxyCODONE-Acetaminophen
Oxycodone-acetaminophen is a combination medication that combines oxycodone, an opioid analgesic, with acetaminophen, a non-opioid pain reliever. This combination is used to treat moderate to severe pain, providing both opioid and non-opioid pain relief for enhanced effectiveness.
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Frequently Asked Questions
How quickly does Oxycodone-acetaminophen work?
Patients may begin to notice pain relief within 30 to 60 minutes after taking the medication.
Can I take Oxycodone-acetaminophen with food?
Yes, it can be taken with or without food; however, taking it with food may help reduce gastrointestinal discomfort.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Are there any dietary restrictions while using Oxycodone-acetaminophen?
There are no specific dietary restrictions, but avoiding alcohol is crucial.
Is Oxycodone-acetaminophen safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Oxycodone-acetaminophen during these periods.
Comprehensive Drug Guide
How Does oxyCODONE-Acetaminophen Work?
- Oxycodone: Works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain and emotional response to pain.
- Acetaminophen: Acts primarily in the central nervous system to inhibit the synthesis of prostaglandins, which are responsible for pain and fever.
Common Dosages
one-acetaminophen is typically available in the following dosage forms:
- Tablets: Common strengths include 5 mg oxycodone/325 mg acetaminophen, 7.5 mg oxycodone/325 mg acetaminophen, and 10 mg oxycodone/325 mg acetaminophen.
Typical Dosing
- The usual recommended dose is 1 tablet taken every 6 hours as needed for pain, with a maximum daily dose not exceeding 4,000 mg of acetaminophen (considering all sources).
Typical Dosing
FDA Approved Indications
- Moderate to Severe Pain: for the management of pain that requires an opioid analgesic.
Who Shouldn't Take oxyCODONE-Acetaminophen?
- Known hypersensitivity to oxycodone, acetaminophen, or any component of the formulation.
- Severe respiratory depression or acute asthma.
- Paralytic ileus.
Advice From The Pharmacist
- Take Oxycodone-acetaminophen exactly as prescribed, and do not exceed the recommended dose to avoid the risk of liver damage from acetaminophen and potential opioid overdose.
- Avoid alcohol and other central nervous system depressants while using this medication.
- Regular follow-ups with your healthcare provider are important to assess pain control and monitor for potential side effects.
Side Effects of oxyCODONE-Acetaminophen
Common Side Effects
- Drowsiness
- Dizziness
- Constipation
- Nausea
- Vomiting
Uncommon/Severe Side Effects
- Respiratory depression (slow or shallow breathing)
- Liver damage (signs include jaundice, dark urine, or abdominal pain)
- Severe allergic reactions (rash, itching, swelling).
Risks and Warnings of oxyCODONE-Acetaminophen
- Risk of Addiction: Oxycodone has a potential for abuse and addiction, especially in individuals with a history of substance use disorder.
- Respiratory Depression: Monitor for signs of respiratory depression, particularly when starting therapy or increasing the dose.
Interactions with oxyCODONE-Acetaminophen
Common Drug Interactions
- Other Opioids: Use with caution when combining with other opioids to avoid excessive sedation and respiratory depression.
- CNS Depressants: Monitor for additive effects when used with benzodiazepines, alcohol, or muscle relaxants.
Alternatives to oxyCODONE-Acetaminophen
- Other Combination Analgesics: Such as hydrocodone-acetaminophen for similar pain management.
- Non-Opioid Pain Relievers: Such as ibuprofen or naproxen for less severe pain.
