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HYDROcodone-Acetaminophen

Hydrocodone-acetaminophen is a combination of an opioid pain reliever (hydrocodone) and a non-opioid pain reliever (acetaminophen). It's used to relieve moderate to severe pain.

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Frequently Asked Questions

Can I drive after taking Hydrocodone-Acetaminophen?
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It's not recommended as it may impair your ability to perform potentially hazardous tasks, like operating heavy machinery or driving a car.

I missed a dose of Hydrocodone-Acetaminophen, what should I do?
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If you miss a dose, take it as soon as you remember. If it's near the time of your next dose, skip the missed dose and resume your usual dosing schedule.

Why do I feel dizzy after taking Hydrocodone-Acetaminophen?
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Dizziness is a common side effect. If you feel dizzy, rest and get up slowly when rising from a sitting or lying position.

Can I drink alcohol with Hydrocodone-Acetaminophen?
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No, you should avoid alcohol while taking this medication. It can increase the risk of liver damage and can also add to the central nervous system effects of hydrocodone.

Can I just stop taking Hydrocodone-Acetaminophen after my pain is gone?
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No, you should consult your healthcare provider before discontinuing any medication. With narcotics like hydrocodone, there could be withdrawal symptoms if the medication is suddenly discontinued.

Comprehensive Drug Guide

How Does HYDROcodone-Acetaminophen Work?

Hydrocodone acts on the central nervous system to alter pain perception. Acetaminophen inhibits prostaglandin synthesis, helping to reduce pain at the source.


What is HYDROcodone-Acetaminophen Used For?

Hydrocodone-acetaminophen is used to treat moderate to severe pain not effectively managed with alternative treatments.


Common Dosages

  • Tablets: 2.5mg/325mg, 5mg/325mg, 7.5mg/325mg, 10mg/325mg 


Typical Dosing

FDA Approved Indications

As prescribed by your healthcare provider. Typical dosing usually involves a tablet every 4 to 6 hours as required for pain relief.


Who Shouldn't Take HYDROcodone-Acetaminophen?

  • Individuals with known hypersensitivity to either hydrocodone or acetaminophen.
  • Patients with significant respiratory depression.
  • Patients with acute or severe bronchial asthma or hypercarbia.
  • Those with known or suspected gastrointestinal obstruction.
  • Pregnant or breastfeeding women should use it with caution as it can pass to the infant.


Advice From The Pharmacist

  • Always follow the dosage and timing prescribed by your healthcare provider.
  • Do not suddenly stop taking the medication; your dosing may have to be gradually decreased.
  • Beware of potential constipation; include dietary fiber and sufficient hydration in your diet.
  • Do not combine with other medications containing acetaminophen.
  • Avoid alcohol while taking this medication as it could increase the risk of liver damage.
  • Use caution while driving or doing anything that requires alertness.


Side Effects of HYDROcodone-Acetaminophen

Common Side Effects

Nausea, vomiting, constipation, lightheadedness, dizziness, or drowsiness may occur.

Uncommon/Severe Side Effects

Slow or shallow breathing, fainting, seizure, liver disease symptoms (such as nausea, vomiting, loss of appetite, stomach/abdominal pain, extreme tiredness, or yellowing eyes/skin)

Risks and Warnings of HYDROcodone-Acetaminophen

  • This medication carries a risk of respiratory depression, liver injury (due to the acetaminophen component), and a risk of dependence and abuse.
  • Hydrocodone-acetaminophen should not be used by patients with severe asthmatic conditions or hypersensitivity to opioids. Chronic use of this medication during pregnancy may lead to neonatal opioid withdrawal syndrome.

Interactions with HYDROcodone-Acetaminophen

Common Drug Interactions

  • Other opioid medications
  • Sedatives or tranquilizers
  • Alcohol
  • Certain antidepressants
  • Certain antipsychotics
  • Certain anticholinergic medications


Alternatives to HYDROcodone-Acetaminophen

  • Tramadol
  • Oxycodone
  • Morphine
  • Codeine
  • Fentanyl
  • Hydromorphone