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Neo-Synalar

Neo-Synalar (neomycin and fluocinolone acetonide) is a topical combination medication that combines an antibiotic and a corticosteroid. It is used to treat skin infections and reduce associated inflammation. Neo-Synalar is effective for conditions such as dermatitis and inflammatory skin disorders that may be complicated by bacterial infections.



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Frequently Asked Questions

How quickly will I see results with Neo-Synalar?
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Many patients notice improvement within a few days of starting treatment, but this can vary based on the severity of the infection.

Can I use Neo-Synalar for all types of skin infections?
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This product is specifically for superficial bacterial infections and should not be used for viral or fungal infections.

What should I do if I miss a dose?
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If you miss a dose, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.

Is it safe to use Neo-Synalar during pregnancy?
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Consult your healthcare provider before using this medication during pregnancy to evaluate potential risks and benefits.

What are the signs of an allergic reaction to watch for?
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Monitor for symptoms such as rash, itching, swelling, or difficulty breathing, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does Neo-Synalar Work?

  • Neomycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, effectively halting the growth of susceptible bacteria.
  • Fluocinolone Acetonide: A corticosteroid that reduces inflammation, redness, and itching by inhibiting the release of inflammatory mediators and suppressing the immune response.


Common Dosages

  • Topical ointment or cream: Specific concentrations of neomycin and fluocinolone acetonide.

Typical Dosing

  • Adults and children: Apply a thin layer of Neo-Synalar to the affected area 2 to 3 times daily, or as directed by a healthcare provider. Cover with a sterile bandage if desired.


Typical Dosing

FDA Approved Indications

  • The treatment of superficial bacterial skin infections and inflammatory conditions.


Who Shouldn't Take Neo-Synalar?

  • Known hypersensitivity to neomycin, fluocinolone acetonide, or any component of the formulation
  • Viral, fungal, or tuberculous infections of the skin


Advice From The Pharmacist

  • Apply Neo-Synalar as directed, using a clean applicator to avoid contamination.
  • Wash your hands thoroughly before and after application.
  • Avoid contact with eyes and mucous membranes; if contact occurs, rinse thoroughly with water.
  • If symptoms do not improve within a few days or worsen, consult your healthcare provider for further evaluation.


Side Effects of Neo-Synalar

Common Side Effects

  • Local irritation (redness, itching, burning)
  • Dryness or peeling of the skin


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Overgrowth of non-susceptible organisms (e.g., fungi)


Risks and Warnings of Neo-Synalar

  • Allergic Reactions: Be vigilant for potential allergic reactions; discontinue use and seek medical attention if severe reactions occur.
  • Skin Sensitivity: Prolonged use may lead to increased skin sensitivity or irritation; monitor the treatment area and consult your healthcare provider if issues arise.


Interactions with Neo-Synalar

Common Drug Interactions

  • Other Topical Medications: Use with caution when applying other topical treatments in the same area, as they may interfere with the effectiveness of Neo-Synalar.


Alternatives to Neo-Synalar

  • Other Topical Antibiotics: Such as mupirocin or clindamycin for similar indications.
  • Topical Corticosteroids: For inflammation without infection, such as hydrocortisone or betamethasone.