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Mupirocin

Mupirocin is an antibiotic ointment applied to the skin to eliminate bacteria causing infections like impetigo, perianal candidiasis, and superficial bacterial infection of skin. Mupirocin on bacterial infections and won't help viral or fungal infections.

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Frequently Asked Questions

Can Mupirocin help with acne?
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Theoretically, Mupirocin can help with acne caused by bacteria. However, this is usually not the first line of treatment for acne.

Does Mupirocin cause side effects?
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While generally well-tolerated, it can cause minor skin irritation when applied. Serious side effects are rare. If you observe any unusual reactions, alert your healthcare provider.

Do I need to apply Mupirocin multiple times a day?
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You typically should apply it three times a day. Follow the specific instructions from your doctor or pharmacist.

Can I use Mupirocin to treat a viral skin infection?
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No, Mupirocin is an antibiotic, and it works only on bacterial infections.

Is Mupirocin available over the counter?
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No, Mupirocin is a prescription medication.

Comprehensive Drug Guide

How Does Mupirocin Work?

Mupirocin is a topical antibiotic that inhibits the multiplication of bacteria by blocking the synthesis of bacterial proteins, necessary for their survival.

Common Dosages

Dosage Forms

  • Ointment: 2%

Typical Dosing

  • For FDA-approved indications:
  • Apply a small amount to the affected area three times per day for 3 to 5 days.


Typical Dosing

FDA Approved Indications

FDA indications: Mupirocin is used to treat skin infections such as impetigo caused by certain bacteria.

Off-Label Uses

Off-label uses: Occasionally it might be used to treat perianal candidiasis and superficial bacterial infections of the skin.

Advice From The Pharmacist

  • This medication is for external use only. Do not use it on the mucous membranes, such as the eyes, nose, or mouth.
  • Apply it on clean skin. Wash your hands before and after applying the ointment.
  • Do not cover the treated area with bandages or other coverings unless directed by your doctor.
  • If symptoms do not improve within 3-5 days, see your doctor.
  • Avoid using mupirocin longer than prescribed to prevent antibiotic resistance.


Side Effects of Mupirocin

Common Side Effects

  • Common side effects: 
  • You might experience a mild burning sensation or stinging when you first apply the ointment, or a possible itch. Most people do not experience significant side effects.
  • Uncommon side effects: 
  • A red, itchy rash (contact dermatitis) can occur but is less common.


Uncommon/Severe Side Effects

  • Rare side effects: 
  • Stop use and seek immediate medical attention if you develop any unusual blisters, swelling, or oozing.


Risks and Warnings of Mupirocin

  • Mupirocin may cause an allergic reaction in those sensitive to it. Discontinue use if you notice severe itching or rash, or any other signs of skin allergy.
  • It may cause a rare but serious condition called Clostridium difficile-associated diarrhea (caused by a type of resistant bacteria) if used for a prolonged period. If you notice abdominal pain or persistent diarrhoea, reach out to your doctor.
  • Avoid contact with the eyes, nostrils or mouth.


Alternatives to Mupirocin

  • Neosporin
  • Polysporin
  • Bacitracin