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Synalar
Synalar (generic name: fluocinolone acetonide) is a topical corticosteroid used to treat a variety of skin conditions, such as eczema, psoriasis, dermatitis, and allergic skin reactions. It works by reducing inflammation, redness, and itching in affected areas of the skin. Synalar is available in different forms, including cream, ointment, gel, and solution, and is typically applied directly to the affected skin. It is generally prescribed for short-term use to control flare-ups of skin conditions.
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Frequently Asked Questions
How long does it take for Synalar to work?
Improvement in symptoms such as itching and inflammation can usually be seen within a few days of starting treatment. However, it may take 1 to 2 weeks for significant improvement, depending on the severity of the condition.
Can Synalar be used on the face?
You should avoid using Synalar on the face unless specifically instructed by your doctor, as the skin on the face is more sensitive and prone to thinning and other side effects.
Is it safe to use Synalar for long periods?
No, Synalar is generally prescribed for short-term use. Long-term use of topical corticosteroids can lead to serious side effects, including skin thinning and adrenal suppression. Consult your doctor if your condition requires long-term treatment.
Can Synalar be used in children?
Synalar can be used in children, but only under the supervision of a healthcare provider, as children are more susceptible to side effects like adrenal suppression. Lower potency corticosteroids may be preferred for pediatric use.
What should I do if I miss a dose?
If you miss a dose, apply the missed dose as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra medication to make up for the missed dose.
Comprehensive Drug Guide
How Does Synalar Work?
Synalar works by activating natural substances in the skin to reduce inflammation, swelling, redness, and itching. As a corticosteroid, it suppresses the immune response that triggers the release of inflammatory substances in the body, thereby providing relief from the symptoms of skin conditions like eczema and psoriasis.
Common Dosages
- 0.01% fluocinolone acetonide topical cream, ointment, solution, and gel
- 0.025% fluocinolone acetonide topical cream and ointment
Typical Dosing
- For inflammatory skin conditions: Apply a thin layer of Synalar to the affected area 1 to 3 times daily, depending on the severity of the condition and the prescribing doctor’s instructions.
- The frequency and duration of use should be kept to the minimum needed to control symptoms, as prolonged use may lead to side effects.
Typical Dosing
FDA Approved Indications
- Eczema
- Psoriasis
- Contact dermatitis
- Seborrheic dermatitis
- Atopic dermatitis
- Other inflammatory and pruritic (itchy) skin conditions
Who Shouldn't Take Synalar?
- Known hypersensitivity to fluocinolone acetonide or any component of the formulation
- Viral, fungal, or bacterial skin infections (unless appropriate antifungal or antibacterial treatment is used)
- Rosacea
- Perioral dermatitis
- Use on broken skin or large areas without medical supervision
Advice From The Pharmacist
- Apply Synalar to clean, dry skin and use only the amount prescribed by your healthcare provider. Avoid using it on large areas of the body or for long periods of time unless directed by your doctor.
- Do not cover the treated area with bandages or dressings unless directed by your doctor, as this can increase the absorption of the medication and risk of side effects.
- Avoid using Synalar on the face, groin, or underarms unless specifically directed, as these areas are more prone to side effects.
- Wash your hands thoroughly after applying the medication unless the hands are the treated area.
- If there is no improvement in your condition after 2 weeks of treatment, consult your doctor.
Side Effects of Synalar
Common Side Effects
- Burning, stinging, or itching at the application site
- Dryness or peeling of the skin
- Redness or irritation
Uncommon/Severe Side Effects
- Skin thinning (atrophy)
- Stretch marks (striae)
- Discoloration of the skin
- Signs of allergic reactions (rash, swelling, difficulty breathing)
- Adrenal suppression with prolonged use, especially in young children or when applied to large areas
Risks and Warnings of Synalar
- Adrenal Suppression: Prolonged use of Synalar, especially in large amounts or over extensive areas of skin, can lead to adrenal insufficiency, where the body’s natural steroid production is suppressed. This can be serious and requires medical supervision.
- Skin Atrophy: Long-term use can cause thinning of the skin, making it more fragile and prone to injury.
- Infection Risk: Using Synalar on open wounds or infected skin can worsen the infection or delay healing. It should not be used on untreated bacterial, viral, or fungal infections.
Interactions with Synalar
Common Drug Interactions
- Topical antifungals or antibacterials: If you are using other topical medications for infections, consult your doctor before combining them with Synalar to avoid reduced effectiveness.
- Other corticosteroids: Using Synalar alongside oral or systemic corticosteroids may increase the risk of side effects, including adrenal suppression.
Alternatives to Synalar
- Hydrocortisone: A milder corticosteroid available over-the-counter and by prescription for less severe skin conditions.
- Betamethasone (Diprolene): A stronger topical corticosteroid used for more severe inflammatory skin conditions.
- Triamcinolone (Kenalog): Another commonly prescribed corticosteroid for inflammatory skin conditions, available in various strengths and forms.
- Non-steroidal topical treatments: For individuals who cannot tolerate corticosteroids, medications like tacrolimus or pimecrolimus may be prescribed for eczema and other inflammatory conditions.
