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Natroba

Natroba (generic name: spinosad) is a topical medication used for the treatment of head lice infestations (pediculosis capitis) in patients aged 4 years and older. It is derived from naturally occurring bacteria and works by targeting the nervous system of lice, leading to their paralysis and death.

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Frequently Asked Questions

How quickly does Natroba work?
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Natroba typically begins to kill lice shortly after application, and results may be visible within a day or two.

Can I use Natroba with other lice treatments?
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Consult your healthcare provider before using other lice treatments concurrently to avoid potential interactions or irritation.

What should I do if I miss a dose?
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If you miss a dose, apply it as soon as you remember. If it’s close to the time for the next application, skip the missed dose and continue with your regular schedule.

Are there any dietary restrictions while using Natroba?
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There are no specific dietary restrictions while using Natroba.

Is Natroba safe during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Natroba during these periods.

Comprehensive Drug Guide

How Does Natroba Work?

Spinosad acts on the nervous system of lice by stimulating the release of neurotransmitters, leading to hyperexcitation, paralysis, and death of the lice. It is effective against both adult lice and their eggs (nits).



Common Dosages

  • Topical Suspension: 0.9% concentration.

Typical Dosing

  • The usual dosing involves applying Natroba to dry hair and scalp, ensuring that the medication is thoroughly distributed. Leave it on for 10 minutes, then rinse with water. The treatment may be repeated if necessary after 7 days.


Typical Dosing

FDA Approved Indications

  • Head Lice Infestation: for the treatment of head lice in individuals aged 4 years and older.


Who Shouldn't Take Natroba?

  • Known hypersensitivity to spinosad or any component of the formulation.
  • Open wounds or irritated skin on the scalp.


Advice From The Pharmacist

  • Apply Natroba only to the scalp and dry hair; do not use it on broken skin.
  • Ensure to follow the instructions carefully for optimal results.
  • Wash hands thoroughly after applying the medication.


Side Effects of Natroba

Common Side Effects

  • Scalp irritation
  • Redness or rash
  • Itching


Uncommon/Severe Side Effects

  • Allergic reactions (rash, swelling, difficulty breathing).


Risks and Warnings of Natroba

  • Irritation: Monitor for signs of irritation or allergic reaction; discontinue use if severe reactions occur.
  • Avoid Contact with Eyes: Ensure the medication does not come into contact with the eyes, as it may cause irritation.


Interactions with Natroba

Common Drug Interactions

  • Other Topical Products: Use caution when applying other topical treatments on the same area, as interactions may affect effectiveness.


Alternatives to Natroba

  • Other Pediculicides: Such as permethrin or ivermectin for treating head lice infestations.
  • Non-pharmacological Treatments: Mechanical removal of lice and nits using a fine-tooth comb may also be considered.