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Nanran
Nanran (oxcarbazepine) is an anticonvulsant medication primarily used to treat partial seizures in adults and children. It can also be used off-label for conditions such as bipolar disorder and neuropathic pain.
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Frequently Asked Questions
How quickly does Nanran work?
Patients may begin to notice a reduction in seizure frequency within a few weeks, but it may take longer to determine optimal efficacy.
Can I take Nanran with food?
Yes, Nanran can be taken with or without food.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Nanran safe during pregnancy?
Consult your healthcare provider before using Nanran during pregnancy to evaluate potential risks and benefits.
What are the signs of serious side effects to watch for?
Monitor for signs of severe allergic reactions or significant changes in mood, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Nanran Work?
Oxcarbazepine works by blocking voltage-gated sodium channels in the brain, stabilizing hyperexcitable neuronal membranes, and reducing the spread of seizure activity. It also modulates neurotransmitter release, which can help in mood stabilization.
Common Dosages
- Tablets: Common strengths include 150 mg, 300 mg, and 600 mg.
- Oral suspension: Usually available in a concentration of 300 mg/5 mL.
Typical Dosing
- Adults: The usual starting dose is 300 mg taken orally twice daily, with potential titration based on clinical response and tolerability, up to a maximum dose of 1200 mg per day.
- Children: Dosage is typically based on body weight and varies with age.
Typical Dosing
FDA Approved Indications
- Treatment of partial seizures in adults and children aged 2 years and older.
Who Shouldn't Take Nanran?
- Known hypersensitivity to oxcarbazepine or any component of the formulation.
- A history of hypersensitivity reactions to carbamazepine.
Advice From The Pharmacist
- Take Nanran exactly as prescribed, and do not stop taking it abruptly without consulting your healthcare provider, as this may increase the risk of seizures.
- Monitor for any signs of mood changes or suicidal thoughts, and report these to your healthcare provider immediately.
- Maintain regular follow-up appointments to monitor efficacy and side effects.
Side Effects of Nanran
Common Side Effects
- Dizziness
- Drowsiness
- Fatigue
- Nausea
- Ataxia (lack of coordination)
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Hyponatremia (low sodium levels, which can cause confusion and seizures)
Risks and Warnings of Nanran
- Suicidal Thoughts: Antiepileptic drugs, including Nanran, may increase the risk of suicidal thoughts or behavior; monitor closely for mood changes.
- Sodium Levels: Periodic monitoring of sodium levels may be necessary, especially in patients at risk for hyponatremia.
Interactions with Nanran
Common Drug Interactions
- Other Anticonvulsants: Inform your healthcare provider about all medications you are taking to avoid potential interactions.
- Oral Contraceptives: Oxcarbazepine may decrease the effectiveness of hormonal contraceptives.
Alternatives to Nanran
- Other Anticonvulsants: Such as lamotrigine or levetiracetam for treating seizures.
- Mood Stabilizers: For mood disorders, alternatives may include lithium or divalproex sodium.
