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OXcarbazepine
Oxcarbazepine is an anticonvulsant or antiepileptic medication. It works by decreasing nerve impulses that cause seizures. Despite some common side effects such as dizziness, drowsiness, fatigue, nausea, and shaky movements, Oxcarbazepine holds the power to transform lives
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Frequently Asked Questions
Can I take Oxcarbazepine if I have kidney disease?
If you have kidney disease, inform your doctor before starting this medicine. Your dose may need to be adjusted or may not be the best choice for you.
Does Oxcarbazepine make you gain weight?
Some people may experience weight gain while taking oxcarbazepine, but it's not a common side effect.
I missed a dose of Oxcarbazepine, what should I do?
Don't panic! If it's close to your next dose, skip the missed one. If not, take it as soon as you remember. But never double up doses!
Can I just stop taking Oxcarbazepine?
No, don't stop the medication suddenly. Your doctor will guide you on how to safely taper off the drug.
Comprehensive Drug Guide
How Does OXcarbazepine Work?
Oxcarbazepine is a voltage-gated sodium channel blocker that inhibits repetitive neuronal firing and halts the propagation of synaptic impulses, thereby reducing seizure episodes.
What is OXcarbazepine Used For?
FDA indications: Oxcarbazepine is used as monotherapy or adjunctive therapy to treat partial seizures and generalized tonic-clonic seizures in adults and children aged 2 years and above.
Off-label uses: It is also used to treat bipolar disorder, neuropathic pain, and anxiety disorders.
Common Dosages
Tablets: 150mg, 300mg, 600mg
Oral Suspension: 300mg/5ml
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- Partial seizures: Starting at 300-600mg per day in two divided doses; gradually increased over two weeks to a maintenance dose of 1200mg daily.
- Tonic-clonic seizures: Start at 300mg per day, divided into two doses, and increase every third day by 300mg until a maintenance dose of 1200mg is reached.
Off-Label Uses
- For off-label uses:
- Neuropathic pain: 600-1800mg in two divided daily doses.
- Bipolar disorder: 300mg twice daily.
Who Shouldn't Take OXcarbazepine?
- Have shown hypersensitivity to Oxcarbazepine or its active metabolite
- Have a history of Aplastic anemia or agranulocytosis
- Have shown Atypical reactions to Carbamazepine
- Suffer from third-degree atrioventricular block
Advice From The Pharmacist
- - Take Oxcarbazepine with or without food.
- - Split your daily dose into two equal portions for better management.
- - Do not stop taking this medication without discussing it with your physician.
- - If you miss a dose, take it as soon as possible, but if it's near your next dose, skip the missed dose.
- - Avoid alcohol and any other central nervous system depressants which may aggravate certain side effects.
- - Inform your doctor if any side effects are persistent or aggravated.
- - Don?t forget to keep yourself hydrated while you?re on Oxcarbazepine therapy.
- Side Effects
Side Effects of OXcarbazepine
Common Side Effects
- - Common side effects:
- - Dizziness, drowsiness, fatigue, nausea, vomiting, headache, double vision, shaky movements, or skin rash.
Uncommon/Severe Side Effects
- - Rare side effects:
- - Memory impairment, mental disturbance, depression, or confusion.
- - Severe side effects:
- - Trouble with walking and coordination; rashes; trouble breathing or swallowing; fever, sore throat, chills, or other signs of infection should be examined by a doctor immediately.
Risks and Warnings of OXcarbazepine
- Patients with rare hereditary conditions such as galactose intolerance should not take this med.
- Oxcarbazepine should be cautiously used in individuals with liver impairment.
- Long-term users should monitor sodium levels as Hyponatraemia is possible.
- Contact the doctor immediately if severe skin reactions occur.
- If the condition worsens or if there is no improvement after 2-3 weeks, contact your doctor.
Interactions with OXcarbazepine
Common Drug Interactions
- Carbamazepine
- Phenytoin
- Phenytoin Sodium XR
- Valproic Acid
Alternatives to OXcarbazepine
- Carbamazepine
- Valproic Acid
- Lamotrigine
- Gabapentin
- Phenobarbital
