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Mounjaro

Mounjaro is a type of medication known as a steroid or corticosteroid. It's highly potent and is administered for a wide range of conditions because of its powerful inflammation-reducing properties. It serves as an effective remedy for conditions like lupus, psoriasis, ulcerative colitis, and various skin disorders. Common side effects include weight gain, mood changes, and difficulty sleeping, but your doctor will usually ensure that the pros of the medication supersede these cons.

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Frequently Asked Questions

Can I take Mounjaro if I have diabetes?
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Yes, you can. However, Mounjaro may increase your blood sugar levels, which will need to be monitored more closely.

Does Mounjaro make you gain weight?
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Yes, Mounjaro can increase your appetite, leading to weight gain in some people.

What should I do if I miss a dose of Mounjaro?
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If it's close to the time for your next dose, then skip the missed dose. If you realize soon after the missed dose, take it as soon as you remember. Never take two doses at once.

Can I just stop taking Mounjaro when I feel better?
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No, never stop taking Mounjaro all of a sudden. Your doctor will likely taper your dose to avoid withdrawal symptoms.

Will Mounjaro affect my mood?
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It might. Mounjaro can cause mood swings in some people. If you start to feel depressed or overly tense, let your doctor know right away.

Comprehensive Drug Guide

How Does Mounjaro Work?

Mounjaro is a potent, synthetic corticosteroid that functions similarly to endogenous hormones. It performs its role by weakening the body's immune response, decreasing inflammation, and adjusting the body's reactions to a variety of diseases.

What is Mounjaro Used For?

FDA Indications: Mounjaro is used to treat a myriad of conditions such as lupus, psoriasis, ulcerative colitis, allergic disorders, endocrine (hormone) disorders, and specific skin, lung, and eye conditions.

Off-label uses: It's also been used for the off-label treatment of severe headaches, and alopecia areata, and for its immunosuppressive properties in organ transplantation.

Common Dosages

Tablets: 2mg, 4mg, 8mg, 16mg, 24mg

Injection solution: 40mg/mL, 125mg/mL

Typical Dosing

FDA Approved Indications

  • For FDA-approved indications:
  • Lupus and psoriasis: 10 to 60mg per day.
  • Ulcerative colitis: 40 to 60mg per day, followed by tapering.

Off-Label Uses

  • For off-label uses:
  • Migraine headaches: 60 to 80mg per day, for 5 to 10 days.
  • Organ transplantation: 20mg per day, along with other immunosuppressive drugs.

Who Shouldn't Take Mounjaro?

  • Have any form of fungal infection.
  • Have a history of tuberculosis.
  • Have certain types of eye infections.
  • Suffer from stomach or duodenal ulcers or have a history of them.
  • Have liver or kidney disease.
  • Have a history of heart disease or a recent heart attack.
  • Have high blood pressure.
  • Are pregnant, planning to become pregnant, or breastfeeding (Mounjaro might cause harm to the baby).
  • Have mental disorders.
  • Have osteoporosis or diabetes.

Advice From The Pharmacist

  • Keep a balanced diet to avoid any potential adverse effects of the drug.
  • Take this medication with food to prevent an upset stomach.
  • Do not stop taking Mounjaro abruptly but taper it off gradually under your doctor?s supervision.
  • Keep all your doctor's appointments and get regular check-ups.
  • If you notice a sudden change in your mood, immediately notify your physician.
  • Became sick or injured? It is important to let your doctor know since Mounjaro can mask the symptoms.
  • Lastly, take each dose at the same time each day to achieve the best results.

Side Effects of Mounjaro

Common Side Effects

  • Common side effects:
  • Increased appetite might result in weight gain.
  • Some people may experience mood swings, outbreaks of anger, or poor-quality sleep.
  • You might experience fluid retention, leading to swelling in the ankles, feet, and fingers.

Uncommon/Severe Side Effects

  • Rare side effects:
  • Unusual tiredness or dizziness.
  • Vision disturbances.
  • Symptoms of serious infection, like fever, persistent sore throat, and painful urination.
  • Sudden weight gain.
  • If you experience severe side effects like irregular heartbeat, mood changes, bloody or tarry stools, and unusual hair growth, get medical help immediately.
  • Severe side effects:
  • Severe abdominal pain
  • Symptoms of a serious allergic reaction like rash, swelling, and severe dizziness.

Risks and Warnings of Mounjaro

  • Doctors must closely monitor patients for changes in behavior or mood, including suicidal thoughts, as these have been reported in patients taking montelukast.
  • It should not be used as a rescue therapy to treat an acute asthma attack.
  • Montelukast can induce an increase in certain white blood cells (eosinophilia), or systemic vasculitis consistent with Churg-Strauss syndrome, a condition often observed in patients with asthma or chronic sinusitis.
  • Notify your healthcare professional if neurologic or psychiatric effects occur while taking this drug.
  • The drug's safety and efficacy in pregnant women have not been established, and thus it should be used only if needed.

Interactions with Mounjaro

Common Drug Interactions

  • Insulin or oral diabetes drugs
  • Cyclosporine
  • Digoxin
  • Warfarin
  • Phenobarbital
  • Ketoconazole
  • Antibiotics like erythromycin

Alternatives to Mounjaro

  • Prednisone
  • Hydrocortisone
  • Cortisone
  • Triamcinolone
  • Dexamethasone