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Methyldopa
Methyldopa is a type of medication classified as an alpha2 adrenergic agonist. It is primarily used to control high blood pressure (hypertension). Some common side effects of Methyldopa include headache, dizziness, and a dry mouth. Your doctor will usually ensure that the benefits of Methyldopa overshadow these issues before prescribing it.
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Frequently Asked Questions
Can I drink alcohol while using Methyldopa
It's advisable to limit alcohol consumption while on Methyldopa. Alcohol can lower your blood pressure and may increase some side effects of Methyldopa.
Can I stop using Methyldopa if my blood pressure is now normal?
Never stop using Methyldopa without consulting your doctor, even if you begin to feel better. Blood pressure might return to previous high levels if the medication is stopped.
Can Methyldopa be used for anxiety?
Methyldopa is not usually prescribed for treating anxiety. Please consult your healthcare provider before using any medication for unapproved uses.
What should I do if I miss a dose?
Take it as soon as you remember. If it's nearly time for your next dose, skip the one you missed. Do not take two doses at once.
Comprehensive Drug Guide
How Does Methyldopa Work?
Methyldopa works as an alpha2 adrenergic agonist, influencing the body's nerve impulses to relax the blood vessels, thereby lowering blood pressure.
What is Methyldopa Used For?
FDA indications: Methyldopa is primarily used to treat hypertension (high blood pressure).
Offlabel uses: Sometimes, Methyldopa is also used offlabel to ease hypertensive crisis episodes or manage high blood pressure during pregnancy.
Common Dosages
Tablets: 250mg, 500mg
Typical Dosing
FDA Approved Indications
- Hypertension: Adults typically start with 250mg two to three times a day, which may be increased over two days to about 0.5 to 2g a day.
Off-Label Uses
- Hypertension: Dosages will be determined by the healthcare provider, typically starting with a lower dose and adjusted as needed.
Who Shouldn't Take Methyldopa?
- Those with a known allergy to Methyldopa or any part of it.
- Individuals with a history of liver disease.
- It may not be suitable for people suffering from kidney disease or on dialysis.
- Caution is advised for those with a history of certain heart conditions like angina.
- People with a history of mental/mood disorders, like depression.
- Methyldopa should be used during pregnancy only if needed. Discuss the risks and benefits with your doctor.
- Breastfeeding moms should consult their healthcare provider before starting Methyldopa, as it can pass into breast milk.
Advice From The Pharmacist
- Methyldopa can cause dizziness, especially in the first couple of days. Stand up slowly to avoid falling.
- It's okay to take Methyldopa with a light meal if it upsets your stomach, but try to use it consistently, either always with food or always without food.
- Try to take your medication at the same time each day to help remember it.
- Do not stop Methyldopa suddenly without talking to your doctor. Stopping suddenly can rapidly increase blood pressure, potentially causing dangerous complications.
- Regular blood tests may be needed to check your liver.
- Limit your intake of alcohol while on Methyldopa, as it could lower your blood pressure too much and cause dizziness.
- Inform your lab technician or dentist about using Methyldopa before receiving any medical or dental care, as it can affect certain lab test results.
- Encourage patients to maintain a lowsodium diet and regular physical activity.
Side Effects of Methyldopa
Common Side Effects
- Feeling dizzy or tired, especially when standing.
- Dry mouth.
- Headache or upset stomach.
Uncommon/Severe Side Effects
- A sudden rash or severe allergic reaction like swelling or difficulty breathing should be reported immediately to a healthcare provider.
Risks and Warnings of Methyldopa
- Methyldopa, although effective for high blood pressure, should not be taken if you are allergic to it.
- If you have a history of certain mental/mood disorders, heart disease, kidney disease, or liver diseases, the use of Methyldopa should be evaluated carefully.
- Caution should be exercised if you are pregnant or breastfeeding.
- Prolonged use of this medication can lead to liver dysfunctions.
Interactions with Methyldopa
Common Drug Interactions
- NSAIDs like ibuprofen (Advil, Motrin) or naproxen (Aleve)
- High blood pressure medications
- Lithium
- MAO inhibitors
- Other Alpha2 adrenergic agonists
Alternatives to Methyldopa
- Hydrochlorothiazide
- Lisinopril
- Amlodipine
- Metoprolol
- Losartan
