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Maxalt-MLT
Maxalt-MLT is a brand name for rizatriptan, a medication specifically designed to treat migraine attacks. It belongs to a class of drugs known as triptans, which work by constricting blood vessels in the brain and blocking pain pathways to alleviate migraine symptoms.
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Frequently Asked Questions
How quickly does Maxalt-MLT work?
Patients often begin to feel relief within 30 minutes to 2 hours after taking Maxalt-MLT
Can I take Maxalt-MLT with food?
Yes, Maxalt-MLT can be taken with or without food, though it's typically used at the onset of migraine symptoms.
What should I do if I miss a dose?
Maxalt-MLT is used on an as-needed basis for migraines, so if you miss a dose and are not experiencing a migraine, you can wait until your next attack to take it.
Are there any dietary restrictions while taking Maxalt-MLT?
There are no specific dietary restrictions associated with Maxalt-MLT, but maintaining a balanced diet is advisable.
Is Maxalt-MLT safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Maxalt-MLT.
Comprehensive Drug Guide
How Does Maxalt-MLT Work?
Rizatriptan works by selectively agonizing serotonin (5-HT) receptors, particularly the 5-HT_1B and 5-HT_1D subtypes. This action leads to vasoconstriction of dilated intracranial blood vessels and inhibition of pro-inflammatory neuropeptides, effectively alleviating headache and associated migraine symptoms.
Common Dosages
- Orally Disintegrating Tablets: 5 mg and 10 mg.
Typical Dosing
- The usual recommended dose is 5 mg to 10 mg taken as soon as a migraine attack begins. If the migraine returns, a second dose may be taken after at least 2 hours. Do not exceed 30 mg in a 24-hour period.
Typical Dosing
FDA Approved Indications
- Acute Treatment of Migraine: to relieve the symptoms of migraine attacks.
Who Shouldn't Take Maxalt-MLT?
- Known hypersensitivity to rizatriptan or any component of the formulation.
- A history of cardiovascular disease, including ischemic heart disease, uncontrolled hypertension, or stroke.
- Use of MAO inhibitors within the last 14 days.
Advice From The Pharmacist
- Take Maxalt-MLT as soon as you feel a migraine coming on for best results.
- Avoid taking more than the recommended dose in a 24-hour period.
- Inform your healthcare provider of any other medications you are taking, especially those that may interact with triptans.
Side Effects of Maxalt-MLT
Common Side Effects
- Dizziness
- Drowsiness
- Fatigue
- Dry mouth
- Nausea
Uncommon/Severe Side Effects
- Signs of heart problems (chest pain, palpitations)
- Severe allergic reactions (rash, itching, swelling)
- Serotonin syndrome (symptoms include confusion, hallucination, seizure).
Risks and Warnings of Maxalt-MLT
- Cardiovascular Risk: Monitor for signs of cardiovascular issues, especially in patients with pre-existing conditions.
- Medication Overuse Headache: Regular use of acute treatments like Maxalt-MLT can lead to rebound headaches if used too frequently.
- Serotonin Syndrome: Be cautious when combining with other serotonergic medications.
Interactions with Maxalt-MLT
Common Drug Interactions
- MAO Inhibitors: Use of MAO inhibitors within 14 days can increase the risk of adverse effects.
- Other Triptans: Avoid use with other triptans to prevent increased risk of side effects.
Alternatives to Maxalt-MLT
- Other Triptans: Such as sumatriptan or zolmitriptan for acute migraine treatment.
- NSAIDs: Nonsteroidal anti-inflammatory drugs like ibuprofen for migraine relief.
- Preventive Medications: Such as beta-blockers or antidepressants for those with frequent migraines.
