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Lomaira
Lomaira is a low-dose formulation of phentermine, a prescription medication used to assist with weight loss in individuals who are obese or overweight and have weight-related medical problems, such as high blood pressure, diabetes, or high cholesterol. It works as an appetite suppressant and belongs to a class of drugs called anorectics or sympathomimetic amines. Lomaira is intended for short-term use alongside a reduced-calorie diet, exercise, and behavioral changes in patients with a body mass index (BMI) of 30 or greater, or 27 or greater with other weight-related health issues.
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Frequently Asked Questions
How quickly does Lomaira start working?
Lomaira starts working within 1-2 hours of taking the dose, helping to suppress appetite around mealtimes. Its effects can last for several hours, which is why it is typically taken before meals.
Can I take Lomaira long-term?
Lomaira is intended for short-term use (a few weeks). Long-term use has not been extensively studied, and the risk of side effects and tolerance increases with prolonged use. Follow your healthcare provider's advice on the duration of treatment.
What should I do if I miss a dose of Lomaira?
If you miss a dose of Lomaira, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Avoid taking a double dose to make up for a missed dose.
Can I drink coffee or caffeinated beverages while taking Lomaira?
It's best to limit or avoid caffeine while taking Lomaira, as combining it with caffeine can increase the risk of side effects like jitteriness, rapid heart rate, and insomnia.
Can Lomaira be used during pregnancy?
Lomaira is not recommended for use during pregnancy, as weight loss is not advised for pregnant women. If you become pregnant while taking Lomaira, inform your healthcare provider immediately.
Comprehensive Drug Guide
How Does Lomaira Work?
Lomaira works by stimulating the central nervous system, including the brain, to increase heart rate and blood pressure while suppressing appetite. It affects the hypothalamus, the part of the brain that controls hunger and satiety, leading to reduced feelings of hunger. Phentermine's stimulant-like effects help patients feel less hungry, allowing them to consume fewer calories and lose weight.
Common Dosages
- 8 mg tablets, which are typically taken up to three times daily, 30 minutes before meals.
Typical Dosing
- The usual dose is 8 mg taken before meals, usually three times a day. Some patients may be prescribed lower or higher doses depending on their response and tolerance.
- Lomaira is intended for short-term use, usually for a few weeks, as long-term safety and efficacy have not been established.
- Patients should take the tablet 30 minutes before a meal to help reduce appetite.
Typical Dosing
FDA Approved Indications
- BMI of 30 or greater (obese)
- BMI of 27 or greater with other risk factors such as hypertension, diabetes, or hyperlipidemia.
Who Shouldn't Take Lomaira?
- A history of cardiovascular disease (e.g., coronary artery disease, stroke, heart failure)
- Uncontrolled high blood pressure (hypertension)
- Hyperthyroidism (overactive thyroid)
- Glaucoma
- A history of drug abuse or dependence
- Known hypersensitivity or allergy to phentermine or any of the ingredients in the formulation
- Patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping such medications
Advice From The Pharmacist
- Lomaira should be taken 30 minutes before meals to suppress appetite and help with portion control during meals.
- Take Lomaira in the morning or early afternoon to avoid insomnia, as it can cause restlessness or difficulty sleeping.
- Lomaira is designed for short-term use, so follow your healthcare provider's instructions carefully and do not exceed the recommended duration.
- Be cautious with caffeine or other stimulants while using Lomaira, as combining them can increase the risk of side effects like jitteriness, palpitations, and anxiety.
- Store Lomaira at room temperature, away from moisture and heat.
Side Effects of Lomaira
Common Side Effects
- Dry mouth
- Insomnia
- Nervousness or anxiety
- Increased heart rate (tachycardia)
- Constipation
- Elevated blood pressure
Uncommon/Severe Side Effects
- Heart palpitations or irregular heartbeats
- Severe mood changes or agitation
- Shortness of breath
- Chest pain
- Signs of an allergic reaction, such as rash, itching, or swelling of the face or throat
Risks and Warnings of Lomaira
- Cardiovascular Risk: Lomaira can increase blood pressure and heart rate. Patients with heart disease or uncontrolled high blood pressure should not use this medication. Regular monitoring of heart rate and blood pressure is recommended during treatment.
- Potential for Abuse: Phentermine, the active ingredient in Lomaira, has stimulant properties and can be habit-forming. It is classified as a Schedule IV controlled substance due to its potential for abuse. Use only as prescribed and avoid sharing the medication with others.
- Central Nervous System Stimulation: Lomaira may cause nervousness, restlessness, or insomnia. Patients should take it early in the day to minimize sleep disturbances.
- Pulmonary Hypertension: There is a rare but serious risk of developing primary pulmonary hypertension, a condition that affects the arteries in the lungs. Report any new or worsening shortness of breath to your healthcare provider immediately.
Interactions with Lomaira
Common Drug Interactions
- Monoamine Oxidase Inhibitors (MAOIs): Using Lomaira with MAOIs (or within 14 days of stopping MAOIs) can lead to dangerous drug interactions, including hypertensive crisis.
- Other stimulants: Combining Lomaira with other stimulant medications (such as amphetamines or over-the-counter decongestants) may increase the risk of side effects like high blood pressure and anxiety.
- SSRIs (e.g., fluoxetine, sertraline): Taking Lomaira with SSRIs or other antidepressants may increase the risk of serotonin syndrome, a rare but potentially life-threatening condition.
- Alcohol: Lomaira may increase the effects of alcohol, leading to an increased risk of side effects like dizziness or drowsiness. It is best to avoid alcohol while using this medication.
Alternatives to Lomaira
- Adipex-P (phentermine): A higher-dose version of phentermine commonly prescribed for short-term weight loss.
- Qsymia (phentermine/topiramate ER): A combination medication that includes phentermine and topiramate (a drug used for seizures and migraines) for long-term weight management.
- Contrave (naltrexone/bupropion): A combination medication that includes an opioid antagonist and an antidepressant, used for weight loss.
- Saxenda (liraglutide): A glucagon-like peptide-1 (GLP-1) receptor agonist, used for weight loss by regulating appetite and food intake.
