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Lacrisert
Lacrisert is the brand name for hydroxypropyl cellulose ophthalmic insert, a sterile, slow-releasing lubricating insert used to treat dry eye syndrome and other conditions that cause severe dryness or irritation of the eyes. It is typically prescribed for individuals with moderate to severe dry eye who have not found relief with artificial tears or other treatments. Lacrisert helps to relieve symptoms by providing long-lasting moisture to the eyes, improving lubrication and protecting the eye's surface.
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Frequently Asked Questions
How long does it take for Lacrisert to start working?
Lacrisert provides continuous lubrication throughout the day once inserted. Some patients may notice relief within a few hours, while others may require several days of regular use to experience full benefits.
Can I use other eye drops with Lacrisert?
Yes, but it is important to wait at least 30 minutes between applying other eye drops and inserting Lacrisert. Consult your doctor for specific instructions regarding your medications.
What should I do if Lacrisert falls out?
If Lacrisert falls out or becomes dislodged, wash your hands and reinsert it if possible. If not, consult your healthcare provider for guidance on whether to use a replacement insert.
Can Lacrisert be used with contact lenses?
Yes, but contact lenses should be removed before inserting Lacrisert and should not be reinserted for at least 30 minutes after placing the insert to ensure proper function.
Is Lacrisert safe for long-term use?
Yes, Lacrisert is generally safe for long-term use under the supervision of a healthcare provider, especially in patients with chronic dry eye syndrome who require continuous lubrication.
Comprehensive Drug Guide
How Does Lacrisert Work?
Lacrisert is a hydroxypropyl cellulose insert that gradually dissolves in the eye, providing long-lasting moisture. It works by slowly releasing a lubricating agent that helps to protect the surface of the eye, stabilizing the tear film, and reducing evaporation of natural tears. This helps to alleviate dryness, irritation, and discomfort caused by conditions such as dry eye syndrome.
Common Dosages
- The typical dose is one insert placed once daily in the lower eyelid, although the frequency can be adjusted depending on the severity of symptoms.
Typical Dosing
- For dry eye syndrome: Insert one Lacrisert ophthalmic insert into the lower eyelid once daily or as directed by your doctor. In some cases, patients may require more frequent use, up to twice daily.
- The insert gradually dissolves over the course of the day, providing continuous lubrication.
Typical Dosing
FDA Approved Indications
- Treatment of moderate to severe dry eye syndrome.
- Management of corneal irritation due to exposure keratitis, decreased corneal sensitivity, or dryness.
Who Shouldn't Take Lacrisert?
- Known hypersensitivity or allergy to hydroxypropyl cellulose or any other components of the formulation.
- Active eye infections or ocular inflammation, as the insert may exacerbate symptoms.
Advice From The Pharmacist
- Wash your hands before handling the insert to avoid contamination.
- Place the insert in the lower eyelid, as instructed by your healthcare provider. If it becomes dislodged, you may need to reposition it.
- Do not rub your eyes after placing the insert, as this may dislodge it.
- Avoid using other eye medications at the same time as Lacrisert, unless directed by your doctor, as they may interfere with the insert's effectiveness.
- Remove contact lenses before inserting Lacrisert, and wait at least 30 minutes before reinserting them.
- Store Lacrisert in a cool, dry place and keep the packaging sealed until ready for use.
Side Effects of Lacrisert
Common Side Effects
- Mild eye discomfort or foreign body sensation after inserting the rod
- Temporary blurred vision or stinging
- Redness or irritation
Uncommon/Severe Side Effects
- Severe eye irritation or allergic reactions (e.g., swelling, redness)
- Dislodged insert, which may require removal by a healthcare provider
Risks and Warnings of Lacrisert
- Foreign Body Sensation: Some patients may experience a foreign body sensation after inserting Lacrisert, especially during the first few days of use. This is typically mild and resolves as the eyes adjust to the treatment.
- Dislodgement: The insert may sometimes dislodge or fall out, particularly if the eye is rubbed or irritated. Repositioning or replacing the insert may be necessary if this happens.
- Ocular Infection: Although rare, improper handling of Lacrisert can introduce bacteria into the eye, leading to infection. Always wash hands before use and follow insertion instructions carefully.
Interactions with Lacrisert
Common Drug Interactions
- Lacrisert has no known significant drug interactions. However, patients should inform their healthcare provider if they are using other ophthalmic products or have any other eye conditions.
Alternatives to Lacrisert
- Artificial tears (over-the-counter): These provide temporary relief from dry eye but may require frequent application.
- Restasis (cyclosporine ophthalmic emulsion): A prescription medication that helps increase tear production in patients with chronic dry eye.
- Xiidra (lifitegrast): Another prescription medication used to treat dry eye disease by reducing inflammation.
- Punctal plugs: Small devices placed in the tear ducts to prevent tears from draining away, helping to retain moisture in the eyes.
