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Restasis
Restasis (cyclosporine ophthalmic emulsion) is a prescription eye drop medication used to treat chronic dry eye disease (keratoconjunctivitis sicca) in adults. It helps increase tear production in patients whose tear production is presumed to be suppressed due to inflammation of the ocular surface. Restasis is a calcineurin inhibitor that works by reducing inflammation and allowing the eyes to produce more natural tears.
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Frequently Asked Questions
How quickly does Restasis start to work?
Patients may start to notice improvements in dry eye symptoms within 4 to 6 weeks of starting Restasis, with optimal effects often seen after 3 to 6 months of consistent use.
Can I use Restasis if I am wearing contact lenses?
Yes, but you must remove your contact lenses before using Restasis and wait at least 15 minutes before reinserting them.
Are there any specific dietary restrictions while using Restasis?
There are no specific dietary restrictions associated with the use of Restasis.
What should I do if I miss a dose of Restasis?
If you miss a dose, instill the missed drop as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Restasis safe for long-term use?
Restasis is generally considered safe for long-term use under medical supervision for managing chronic dry eye disease. Regular follow-up appointments are important to monitor effectiveness and any potential side effects.
Comprehensive Drug Guide
How Does Restasis Work?
- Inhibiting T-lymphocyte activation: Cyclosporine inhibits the activation of T-cells, which play a role in inflammation. By reducing this inflammation, Restasis helps restore the natural production of tears.
- Promoting tear production: By addressing the underlying inflammation, the medication can help the lacrimal glands (tear glands) function better, increasing natural tear output.
Common Dosages
- Ophthalmic emulsion: Each vial contains 0.05% cyclosporine.
Typical Dosing
- The recommended dosing for adults is to instill one drop in each eye twice daily (approximately 12 hours apart). Consistent use is crucial for optimal results.
Typical Dosing
FDA Approved Indications
- Increased tear production in patients with chronic dry eye disease.
Who Shouldn't Take Restasis?
- Known hypersensitivity to cyclosporine or any components of the formulation.
- Active ocular infections.
Advice From The Pharmacist
- Instruct patients on the proper technique for applying Restasis, emphasizing the importance of avoiding touching the tip of the vial to any surface, including the eye.
- Advise patients to wait at least 15 minutes before using any other eye drops after applying Restasis to ensure proper absorption.
- Discuss the importance of regular follow-up appointments to monitor the effectiveness of treatment and manage any potential side effects.
Side Effects of Restasis
Common Side Effects
- Burning or stinging sensation upon application
- Redness of the eye
- Discharge from the eye
- Eye pain
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Eye infections.
Risks and Warnings of Restasis
- Infection Risk: Patients should be monitored for signs of eye infection, especially if they experience increased redness, swelling, or discharge.
- Contact Lens Use: Patients wearing contact lenses should remove them before applying Restasis and wait at least 15 minutes before reinserting them.
Interactions with Restasis
Common Drug Interactions
- Other Ophthalmic Medications: Patients should inform their healthcare provider about all medications they are using, especially other eye drops or medications that may affect tear production.
Alternatives to Restasis
- Other Dry Eye Treatments: Alternatives may include artificial tears, punctal plugs, or other medications like lifitegrast or other anti-inflammatory agents depending on individual patient needs and preferences.
