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Fanapt
Fanapt (generic name: iloperidone) is an atypical antipsychotic used to treat schizophrenia in adults. It works by affecting the levels of certain neurotransmitters in the brain, particularly dopamine and serotonin, which helps to reduce psychotic symptoms such as hallucinations, delusions, and disorganized thinking.
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Frequently Asked Questions
How long does it take for Fanapt to start working?
It may take several weeks to notice significant improvements in symptoms, though some patients may experience relief earlier.
Can Fanapt cause weight gain?
Yes, weight gain is a common side effect of Fanapt and other antipsychotics.
Can I drink alcohol while taking Fanapt?
Avoid alcohol while taking Fanapt, as it can increase the risk of drowsiness, dizziness, and other side effects.
What should I do if I miss a dose of Fanapt?
If you miss a dose, take it as soon as you remember unless it’s close to your next scheduled dose. Do not double up on doses.
Is Fanapt safe for long-term use?
Fanapt is often used for long-term management of schizophrenia, but regular monitoring by your healthcare provider is important to ensure its continued safety and effectiveness.
Comprehensive Drug Guide
How Does Fanapt Work?
Fanapt works by blocking dopamine D2 and serotonin 5-HT2A receptors in the brain, which helps regulate mood, cognition, and behavior in patients with schizophrenia.
Common Dosages
- 1 mg, 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, and 12 mg tablets.
Typical Dosing
- The typical starting dose is 1 mg twice daily, which is gradually increased to a maintenance dose of 6 mg to 12 mg twice daily.
Typical Dosing
FDA Approved Indications
- Schizophrenia in adults
Who Shouldn't Take Fanapt?
- Known hypersensitivity to iloperidone.
- History of QT prolongation or taking medications that may cause QT prolongation.
Advice From The Pharmacist
- Fanapt should be taken twice daily. It can be taken with or without food, but try to take it at the same time each day.
- Do not stop taking Fanapt abruptly without consulting your healthcare provider, as this may worsen symptoms of schizophrenia.
- Fanapt may cause dizziness or lightheadedness, especially when standing up quickly. Rise slowly from sitting or lying positions to reduce the risk of falls.
Side Effects of Fanapt
Common Side Effects
- Dizziness
- Dry mouth
- Fatigue
- Weight gain
Uncommon/Severe Side Effects
- Tardive dyskinesia (involuntary movements)
- Orthostatic hypotension
- QT prolongation
Risks and Warnings of Fanapt
- QT Prolongation: Fanapt can cause QT prolongation, a heart rhythm disorder that can lead to serious complications. Patients with heart conditions or those taking medications that affect the heart rhythm should be monitored closely.
- Tardive Dyskinesia: Long-term use of antipsychotics can cause tardive dyskinesia, which involves involuntary muscle movements.
Interactions with Fanapt
Common Drug Interactions
- CYP3A4 and CYP2D6 inhibitors: Medications that inhibit these enzymes, such as fluoxetine or ketoconazole, may increase iloperidone levels, increasing the risk of side effects.
- Medications that prolong the QT interval: Combining Fanapt with other medications that prolong the QT interval can increase the risk of heart rhythm issues.
Alternatives to Fanapt
- Risperdal (risperidone): Another atypical antipsychotic used for schizophrenia.
- Seroquel (quetiapine): Another option for treating schizophrenia and bipolar disorder.
- Abilify (aripiprazole): A newer antipsychotic that can be used for schizophrenia, bipolar disorder, and depression.
