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Eysuvis
Eysuvis (generic name: loteprednol etabonate) is an ophthalmic corticosteroid used for the short-term treatment of dry eye disease and ocular inflammation. It is specifically designed to relieve eye redness, itching, and discomfort caused by dry eye flare-ups. Eysuvis reduces inflammation in the eye by suppressing the immune response, thereby reducing the symptoms associated with dry eye disease.
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Frequently Asked Questions
How long does it take for Eysuvis to work?
Eysuvis typically starts relieving dry eye symptoms within a few days of starting treatment, but full benefits may take up to one week.
Can I use Eysuvis with other dry eye treatments?
Yes, Eysuvis can be used alongside other dry eye treatments, such as artificial tears or Restasis. However, wait at least 5 minutes between different eye drops to prevent dilution.
What should I do if I miss a dose of Eysuvis?
If you miss a dose, apply it as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can I wear contact lenses while using Eysuvis?
No, you should remove contact lenses before using Eysuvis and wait at least 15 minutes after applying the drops before reinserting them
Is Eysuvis safe for long-term use?
Eysuvis is intended for short-term use only (up to two weeks). Prolonged use of corticosteroids can increase the risk of side effects such as glaucoma or cataracts, so it is important to follow your doctor's instructions.
Comprehensive Drug Guide
How Does Eysuvis Work?
Eysuvis works by suppressing the release of substances in the body that cause inflammation, such as prostaglandins and cytokines. This reduces swelling, redness, itching, and discomfort in the eyes, particularly during dry eye disease flare-ups.
Common Dosages
- For dry eye disease: Instill one to two drops in the affected eye(s) four times a day. Treatment is usually limited to two weeks, as prolonged use of corticosteroids can increase the risk of side effects such as increased eye pressure or cataracts.
- Shake the bottle well before each use to ensure the suspension is evenly mixed.
Typical Dosing
FDA Approved Indications
- Short-term treatment of the signs and symptoms of dry eye disease, specifically to treat inflammation and discomfort during flare-ups.
Who Shouldn't Take Eysuvis?
- Known hypersensitivity to loteprednol or any components of the formulation.
- Active eye infections, including viral, bacterial, or fungal infections of the eye, as corticosteroids can worsen infections.
- Untreated glaucoma, due to the risk of increased intraocular pressure.
Advice From The Pharmacist
- Shake the bottle well before each use, and administer the drops as directed by your healthcare provider.
- Do not touch the tip of the dropper to your eye or any other surface to avoid contamination.
- If you wear contact lenses, remove them before applying Eysuvis and wait at least 15 minutes before reinserting them.
- If you are using other eye drops, wait at least 5 minutes between applying Eysuvis and other medications.
- Report any signs of blurred vision, eye pain, or visual changes to your healthcare provider immediately, as these may indicate increased eye pressure or other serious side effects.
Side Effects of Eysuvis
Common Side Effects
- Blurred vision
- Eye irritation or discomfort
- Headache
- Dry eye sensation
Uncommon/Severe Side Effects
- Increased intraocular pressure (leading to glaucoma)
- Cataracts with long-term use
- Eye infections (due to immunosuppressive effects)
- Allergic reactions (rash, itching, swelling)
Risks and Warnings of Eysuvis
- Increased Intraocular Pressure: Prolonged use of corticosteroids, including Eysuvis, may lead to increased intraocular pressure, which can cause glaucoma. Regular monitoring of eye pressure is recommended for patients on extended corticosteroid treatment.
- Cataracts: Long-term use of corticosteroids can lead to the development of posterior subcapsular cataracts.
- Delayed Wound Healing: Corticosteroids can delay healing of corneal injuries, so caution is advised in patients with corneal damage.
- Infection Risk: Eysuvis may increase the risk of eye infections, including fungal or viral infections, due to its immunosuppressive effects.
Interactions with Eysuvis
Common Drug Interactions
- Other corticosteroid eye drops: Combining Eysuvis with other corticosteroid eye drops may increase the risk of glaucoma and cataracts.
- Antibiotic or antiviral eye medications: If you have an eye infection, using Eysuvis without proper treatment may worsen the infection.
Alternatives to Eysuvis
- Restasis (cyclosporine): An eye drop used for chronic dry eye disease, particularly to increase tear production.
- Xiidra (lifitegrast): An anti-inflammatory eye drop used to treat the signs and symptoms of dry eye disease.
- Lotemax (loteprednol etabonate): Another corticosteroid eye drop, but with a higher concentration of loteprednol, used for treating inflammation in the eyes.
- Over-the-counter artificial tears: Non-prescription eye drops that provide relief for dry eyes without corticosteroids.
