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Epsolay

Epsolay (generic name: benzoyl peroxide 5% cream) is a topical medication used to treat inflammatory rosacea. It is the first benzoyl peroxide formulation specifically approved for treating rosacea, a chronic skin condition characterized by redness, bumps, and inflammation on the face. Epsolay works by reducing the bacteria on the skin's surface and decreasing inflammation, leading to improved skin appearance.



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Frequently Asked Questions

How long does it take for Epsolay to improve rosacea?
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Most patients begin to see improvement in their rosacea symptoms within 4 to 8 weeks of consistent use.

Can I use Epsolay with makeup?
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Yes, you can apply makeup after using Epsolay, but allow the cream to dry fully before applying makeup.

Is Epsolay safe for sensitive skin?
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Epsolay may cause irritation in patients with sensitive skin. If irritation occurs, reduce the frequency of application or consult your healthcare provider.

Can Epsolay be used for acne?
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Although Epsolay contains benzoyl peroxide, which is commonly used for acne, it is specifically formulated and approved for rosacea. Consult your doctor for acne treatment options.

Can I use Epsolay with other skincare products?
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Yes, but avoid using harsh or drying skincare products (like astringents or exfoliants) alongside Epsolay, as this can increase irritation.

Comprehensive Drug Guide

How Does Epsolay Work?

Epsolay works by releasing benzoyl peroxide, which has both antimicrobial and anti-inflammatory properties. It helps to reduce the number of bacteria on the skin that can contribute to rosacea flare-ups, and it also decreases the redness and swelling associated with inflammatory rosacea.



Common Dosages

  • 5% benzoyl peroxide

Typical Dosing

  • Apply a thin layer of Epsolay to the affected areas of the face once daily, as directed by your healthcare provider.


Typical Dosing

FDA Approved Indications

  • Inflammatory lesions of rosacea in adults


Who Shouldn't Take Epsolay?

  • Hypersensitivity to benzoyl peroxide or any other ingredients in the formulation.
  • Severe skin irritation or known sensitivity to peroxide compounds.


Advice From The Pharmacist

  • Epsolay is for external use only. Avoid contact with the eyes, mouth, and other mucous membranes.
  • Wash your hands thoroughly after applying Epsolay.
  • Epsolay may bleach hair or fabric (such as clothing, towels, or bedding), so be cautious after application.
  • Avoid prolonged exposure to sunlight or tanning beds while using Epsolay, as the skin may become more sensitive to UV light.


Side Effects of Epsolay

Common Side Effects

  • Dryness or peeling of the skin
  • Redness or itching
  • Mild irritation at the application site


Uncommon/Severe Side Effects

  • Severe skin irritation or rash
  • Allergic reactions


Risks and Warnings of Epsolay

  • Skin Irritation: Epsolay may cause dryness, redness, or peeling. If severe irritation occurs, reduce the frequency of use or discontinue use as directed by your healthcare provider.
  • Photosensitivity: Epsolay can increase the skin's sensitivity to sunlight, leading to sunburns. Use sunscreen and protective clothing when outdoors.


Interactions with Epsolay

Common Drug Interactions

  • Topical retinoids: Using Epsolay with retinoids (e.g., tretinoin) may increase skin irritation.
  • Topical antibiotics: Combining Epsolay with other topical antibiotics (e.g., clindamycin) may enhance the effectiveness against inflammatory lesions.


Alternatives to Epsolay

  • Soolantra (ivermectin 1% cream): Another topical treatment for inflammatory rosacea.
  • MetroGel (metronidazole gel): A topical antibiotic commonly used for rosacea.
  • Finacea (azelaic acid): A topical treatment for rosacea that reduces inflammation and improves skin texture.