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Diflorasone Diacetate
Diflorasone Diacetate is a high-potency topical corticosteroid used to treat inflammatory skin conditions, such as eczema, psoriasis, and dermatitis. It helps reduce redness, swelling, and itching by suppressing the immune response and decreasing inflammation in the affected areas. This medication is typically used for short-term treatment in adults and is applied directly to the skin.
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Frequently Asked Questions
How long does it take for Diflorasone Diacetate to work?
You should notice improvements in symptoms like itching and redness within a few days of starting treatment.
Can Diflorasone Diacetate be used on the face?
It is not recommended for use on the face unless specifically directed by your healthcare provider, as the skin on the face is more prone to thinning and irritation.
What should I do if I miss a dose?
Apply the missed dose as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra medication to make up for the missed dose.
Is Diflorasone Diacetate safe for long-term use?
Diflorasone Diacetate is generally intended for short-term use due to the risk of side effects like skin thinning. Long-term use should only be under the supervision of a healthcare provider.
Can Diflorasone Diacetate cause weight gain?
While rare with topical use, systemic absorption of corticosteroids from prolonged or excessive use can cause side effects like weight gain and fluid retention. Always follow your healthcare provider’s instructions to avoid such risks.
Comprehensive Drug Guide
How Does Diflorasone Diacetate Work?
Diflorasone Diacetate works by inhibiting the release of substances in the body that cause inflammation, such as prostaglandins and leukotrienes. This action helps to reduce the inflammatory response, relieving symptoms like redness, swelling, and itching.
What is Diflorasone Diacetate Used For?
- Relief of inflammation and itching associated with corticosteroid-responsive dermatoses, including eczema, psoriasis, and dermatitis
Common Dosages
Diflorasone Diacetate is available in the following formulations:
- 0.05% cream
- 0.05% ointment
Typical Dosing
FDA Approved Indications
- Apply a thin layer of Diflorasone Diacetate to the affected area once or twice daily, as prescribed by your healthcare provider. Avoid using this medication on the face, groin, or underarms unless directed by a healthcare provider.
Who Shouldn't Take Diflorasone Diacetate?
Diflorasone Diacetate should not be used in individuals with:
- Untreated skin infections (bacterial, fungal, or viral)
- Hypersensitivity to corticosteroids or any of the ingredients in the formulation
Advice From The Pharmacist
- Do not apply Diflorasone Diacetate to broken or infected skin unless directed by a healthcare provider.
- Avoid using tight dressings or bandages over the treated area unless instructed, as this can increase absorption and lead to side effects.
- Use the medication only for the prescribed duration. Prolonged use of corticosteroids can lead to skin thinning and other side effects.
- Contact your healthcare provider if the condition worsens or does not improve after two weeks of treatment.
Side Effects of Diflorasone Diacetate
Common Side Effects
- Mild burning or stinging at the application site
- Skin dryness or irritation
- Redness
Uncommon/Severe Side Effects
- Skin thinning (atrophy) with prolonged use
- Stretch marks
- Allergic contact dermatitis
- Adrenal suppression (if absorbed systemically with prolonged use)
Risks and Warnings of Diflorasone Diacetate
Skin Thinning: Prolonged use of high-potency corticosteroids like Diflorasone Diacetate can cause thinning of the skin, especially in sensitive areas like the face and groin.
Systemic Absorption: When applied to large areas of the body or used under occlusive dressings, Diflorasone Diacetate can be absorbed into the bloodstream and cause systemic side effects, including adrenal suppression.
Infections: Corticosteroids can mask signs of infection or worsen existing skin infections. Discontinue use and contact your healthcare provider if you suspect an infection.
Interactions with Diflorasone Diacetate
Common Drug Interactions
- Other topical medications: Using multiple topical treatments simultaneously can increase the risk of irritation or overuse of corticosteroids.
- Occlusive dressings: Using these can enhance the absorption of Diflorasone Diacetate, increasing the risk of systemic side effects.
Alternatives to Diflorasone Diacetate
- Hydrocortisone 2.5%: A lower-potency corticosteroid used for mild inflammatory skin conditions.
- Clobetasol Propionate 0.05%: A higher-potency corticosteroid used for severe skin conditions.
- Tacrolimus (Protopic): A non-steroidal topical immunomodulator used for the treatment of eczema.
- Calcipotriene (Dovonex): A non-steroidal treatment for plaque psoriasis.
