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Detrol
Detrol (tolterodine tartrate) is an antimuscarinic medication used to treat overactive bladder (OAB) symptoms, including urinary frequency, urgency, and urge incontinence. By relaxing the muscles in the bladder, Detrol helps reduce the frequency of urination and the sudden need to urinate, improving overall bladder control in patients with OAB.
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Frequently Asked Questions
How long does it take for Detrol to start working?
You may start to notice improvements in bladder control within the first week, but it may take 4 to 8 weeks for the full benefits to become noticeable.
Can I stop taking Detrol if my symptoms improve?
Do not stop taking Detrol without consulting your healthcare provider, even if your symptoms improve. Your provider will guide you on how to safely discontinue the medication if needed.
What should I do if I miss a dose of Detrol?
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
What should I do if I miss a dose of Detrol?
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Can Detrol cause weight gain?
Weight gain is not a common side effect of Detrol. However, if you experience significant weight changes, consult your healthcare provider.
Is Detrol safe for long-term use?
Yes, Detrol is generally safe for long-term use when taken as prescribed. Regular follow-up appointments with your healthcare provider are recommended to monitor for any side effects or changes in bladder function.
Comprehensive Drug Guide
How Does Detrol Work?
Detrol works by blocking muscarinic receptors in the bladder, reducing involuntary bladder contractions and allowing the bladder to store more urine. This helps alleviate symptoms of urgency and incontinence by reducing bladder overactivity.
What is Detrol Used For?
Treatment of overactive bladder (OAB) with symptoms of urgency, frequency, and urge incontinence
Common Dosages
Detrol is available in the following strengths:
- 1 mg tablets
- 2 mg tablets
Typical Dosing
FDA Approved Indications
The usual starting dose for adults is 2 mg twice daily. Based on the patient's response and tolerance, the dose may be reduced to 1 mg twice daily.
Who Shouldn't Take Detrol?
Detrol should not be used in individuals with:
- Urinary retention
- Gastric retention
- Uncontrolled narrow-angle glaucoma
- Known hypersensitivity to tolterodine or any other ingredients in the formulation
Advice From The Pharmacist
- Take Detrol at the same time each day, with or without food. Swallow the tablet whole and do not crush or chew it.
- Drink plenty of water and maintain hydration, as antimuscarinic medications can lead to dry mouth and reduced sweating.
- If you experience difficulty urinating or notice that your bladder is not emptying completely, contact your healthcare provider immediately.
- Avoid activities that require alertness, such as driving, until you know how Detrol affects you, as it may cause dizziness or drowsiness.
Side Effects of Detrol
Common Side Effects
- Dry mouth
- Constipation
- Headache
- Drowsiness
- Blurred vision
Uncommon/Severe Side Effects
- Urinary retention
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
- Confusion or memory problems
Risks and Warnings of Detrol
Urinary Retention: In some patients, especially those with pre-existing urinary issues, Detrol may cause or worsen urinary retention. Patients should be monitored for difficulty urinating.
Cognitive Impairment: Detrol may cause drowsiness, confusion, or memory problems in some patients. Caution is advised when performing tasks that require full alertness.
Increased Glaucoma Risk: Patients with narrow-angle glaucoma should use Detrol with caution, and those with uncontrolled glaucoma should avoid its use.
Interactions with Detrol
Common Drug Interactions
- Other anticholinergic medications: Using Detrol with other anticholinergic drugs can increase the risk of side effects such as dry mouth, constipation, and blurred vision.
- Ketoconazole and other CYP3A4 inhibitors: These medications can increase tolterodine levels, raising the risk of side effects.
- Medications that slow gastric motility: Combining Detrol with other medications that slow digestion may increase the risk of gastric retention.
Alternatives to Detrol
- Oxybutynin (Ditropan): Another antimuscarinic medication used for overactive bladder.
- Solifenacin (Vesicare): A long-acting antimuscarinic for the treatment of OAB.
- Myrbetriq (mirabegron): A beta-3 adrenergic agonist used to treat OAB by relaxing the bladder without using anticholinergic effects.
- Trospium (Sanctura): An anticholinergic drug used for the treatment of OAB.
