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Depo-SubQ Provera 104
Depo-SubQ Provera 104 is a progestin-only injectable contraceptive that contains medroxyprogesterone acetate. It is used for the prevention of pregnancy and the management of endometriosis-associated pain. Administered as a subcutaneous injection, this formulation delivers a lower dose of medroxyprogesterone compared to Depo-Provera, but provides similar contraceptive effects. Each injection lasts for approximately three months, and it works by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining.
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Frequently Asked Questions
How long does it take for Depo-SubQ Provera 104 to start working?
Depo-SubQ Provera 104 is effective within 24 hours if given during the first five days of your menstrual cycle. If given at another time, you should use backup contraception for seven days.
Can I stop using Depo-SubQ Provera 104 at any time?
Yes, you can stop using Depo-SubQ Provera 104 at any time, but keep in mind that it may take several months to a year for your fertility to return.
What should I do if I miss my scheduled Depo-SubQ Provera 104 injection?
If you miss your injection by more than two weeks, use a backup contraceptive method and contact your healthcare provider to schedule the next injection.
Does Depo-SubQ Provera 104 cause weight gain?
Weight gain is a common side effect. Some women may experience significant weight changes over time, so monitoring your weight and maintaining a healthy lifestyle is recommended.
Does Depo-SubQ Provera 104 protect against sexually transmitted infections (STIs)?
No, Depo-SubQ Provera 104 does not protect against STIs. Use condoms or other barrier methods to prevent sexually transmitted infections.
Comprehensive Drug Guide
How Does Depo-SubQ Provera 104 Work?
Depo-SubQ Provera 104 prevents pregnancy by delivering medroxyprogesterone acetate, which suppresses the release of gonadotropins (LH and FSH). This action prevents ovulation, thickens cervical mucus to impede sperm penetration, and alters the uterine lining to prevent implantation.
What is Depo-SubQ Provera 104 Used For?
- Prevention of pregnancy
- Management of endometriosis-associated pain
Common Dosages
Depo-SubQ Provera 104 is available as a pre-filled syringe containing:
- 104 mg of medroxyprogesterone acetate per 0.65 mL for subcutaneous injection.
Typical Dosing
FDA Approved Indications
- The recommended dose is 104 mg injected subcutaneously every 12-14 weeks. It is important to receive the injection on time every three months to maintain contraceptive efficacy.
Who Shouldn't Take Depo-SubQ Provera 104?
Depo-SubQ Provera 104 should not be used in individuals with:
- Active thromboembolic disorders
- Known or suspected breast cancer
- Liver disease
- Unexplained vaginal bleeding
- Known hypersensitivity to medroxyprogesterone or any other ingredients in the formulation
Advice From The Pharmacist
- Depo-SubQ Provera 104 should be administered by a healthcare provider. Ensure you receive your injection every 12 to 14 weeks to maintain protection against pregnancy.
- This formulation may cause changes in your menstrual cycle, including irregular bleeding or amenorrhea (absence of periods).
- Long-term use of Depo-SubQ Provera 104 may lead to bone density loss. Consider discussing calcium and vitamin D supplementation with your healthcare provider.
- Depo-SubQ Provera 104 does not protect against sexually transmitted infections (STIs). You may need to use additional barrier protection methods such as condoms.
Side Effects of Depo-SubQ Provera 104
Common Side Effects
- Irregular bleeding or spotting
- Weight gain
- Headache
- Abdominal pain
- Decreased bone mineral density
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
- Signs of blood clots (e.g., leg pain, chest pain, shortness of breath)
- Severe abdominal or pelvic pain
Risks and Warnings of Depo-SubQ Provera 104
Bone Density Loss: Long-term use of Depo-SubQ Provera 104 may result in a loss of bone mineral density, particularly in adolescents and young women. The risk increases with the duration of use, so consider using this contraceptive for the shortest time possible.
Weight Gain: Some women may experience weight gain while using Depo-SubQ Provera 104. Maintaining a balanced diet and engaging in regular physical activity can help manage this side effect.
Delayed Fertility: Fertility may take several months to return after stopping Depo-SubQ Provera 104. In some cases, it can take up to a year or longer for regular ovulation to resume.
Interactions with Depo-SubQ Provera 104
Common Drug Interactions
- Corticosteroids: Concomitant use with corticosteroids may increase the risk of bone density loss.
- Aminoglutethimide: This medication may reduce the effectiveness of Depo-SubQ Provera 104.
- Other hormonal contraceptives: Avoid using other hormonal contraceptives while on Depo-SubQ Provera 104 unless instructed by your healthcare provider.
Alternatives to Depo-SubQ Provera 104
- Depo-Provera: An intramuscular formulation of medroxyprogesterone acetate used for contraception.
- Nexplanon: A long-acting contraceptive implant that lasts up to three years.
- Mirena: A hormonal intrauterine device (IUD) providing contraceptive protection for up to five years.
- Oral contraceptives: Combination birth control pills that must be taken daily.
