You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
cloNIDine HCl
Clonidine HCl is a centrally-acting alpha-2 adrenergic agonist used primarily to treat high blood pressure (hypertension) by reducing heart rate and relaxing blood vessels. It is also prescribed for attention-deficit hyperactivity disorder (ADHD) in children, as well as for managing withdrawal symptoms from opioids and alcohol. Clonidine HCl can help reduce anxiety, manage pain, and provide sedation in certain medical contexts. It is available in tablet, extended-release, and transdermal patch forms.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with cloNIDine HCl ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Clonidine HCl to work?
Clonidine begins lowering blood pressure within 30 to 60 minutes after oral administration. For ADHD or withdrawal symptoms, it may take a few days for the full therapeutic effect to be noticeable.
Can Clonidine HCl be used in children?
Yes, Clonidine HCl is approved for use in children, especially for ADHD. The extended-release form is typically used, and dosing is adjusted based on the child’s response to the medication.
Is Clonidine HCl safe during pregnancy?
Clonidine should be used during pregnancy only if the potential benefits outweigh the risks. Consult your healthcare provider if you are pregnant or planning to become pregnant while taking this medication.
What should I do if I miss a dose of Clonidine HCl?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
Can Clonidine HCl cause weight gain?
Clonidine may cause mild weight gain in some individuals due to its sedative effects and influence on metabolic rate. Maintaining a healthy diet and exercising regularly may help mitigate this side effect.
Comprehensive Drug Guide
How Does cloNIDine HCl Work?
Clonidine HCl works by stimulating alpha-2 adrenergic receptors in the brain, reducing the release of norepinephrine. This action decreases sympathetic nervous system activity, leading to a lower heart rate and relaxed blood vessels, which in turn lowers blood pressure. In ADHD, it helps modulate hyperactivity by affecting brain receptors involved in attention and behavior.
What is cloNIDine HCl Used For?
Common Dosages
- Tablets: 0.1 mg, 0.2 mg, 0.3 mg
- Extended-release tablets (ADHD): 0.1 mg, 0.2 mg
- Transdermal patches: 0.1 mg/24 hours, 0.2 mg/24 hours, 0.3 mg/24 hours
Typical Dosing
- For hypertension: The typical starting dose is 0.1 mg twice daily, which may be increased by 0.1 mg per week as needed. The maximum recommended dose is 0.8 mg per day.
- For ADHD: Extended-release Clonidine HCl is usually started at 0.1 mg at bedtime, with gradual increases up to 0.4 mg per day, as needed.
- For withdrawal symptoms: Clonidine HCl is typically dosed at 0.1-0.3 mg every 6-8 hours as needed, under medical supervision.
Typical Dosing
FDA Approved Indications
- Hypertension
- Attention-deficit hyperactivity disorder (ADHD) in children and adolescents (extended-release formulation)
Off-Label Uses
- Management of withdrawal symptoms from opioids and alcohol
- Treatment of anxiety disorders and panic attacks
- Migraine prevention
- Pain management (as part of a multi-drug approach)
Pediatric Dosing
Clonidine is approved for use in children for the treatment of ADHD. The dose should be determined by the healthcare provider.
Who Shouldn't Take cloNIDine HCl?
- Known hypersensitivity to clonidine or any formulation components
- Severe heart disease, such as advanced heart block or sick sinus syndrome, without a pacemaker
- Low blood pressure (hypotension)
Advice From The Pharmacist
- Take Clonidine HCl as directed by your healthcare provider, and do not abruptly stop the medication. Stopping suddenly may cause dangerous spikes in blood pressure (rebound hypertension).
- Clonidine HCl may cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you.
- Avoid alcohol or other sedatives while taking Clonidine HCl, as this may increase drowsiness and dizziness.
- If using the transdermal patch, apply it to a clean, dry area of the skin and change it every 7 days.
Side Effects of cloNIDine HCl
Common Side Effects
- Dry mouth
- Drowsiness or fatigue
- Dizziness or lightheadedness
- Constipation
- Headache
Uncommon/Severe Side Effects
- Bradycardia (slow heart rate)
- Hypotension (low blood pressure)
- Rebound hypertension (after abrupt discontinuation)
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of cloNIDine HCl
- Rebound Hypertension: Abrupt discontinuation of Clonidine can lead to a rapid increase in blood pressure (rebound hypertension). Always taper the dose gradually under the guidance of your healthcare provider.
- Sedation and Drowsiness: Clonidine can cause significant sedation, especially when combined with alcohol or other central nervous system depressants. Use caution when performing tasks that require full alertness.
- Bradycardia and Hypotension: Clonidine may cause a decrease in heart rate and blood pressure. If you experience lightheadedness or fainting, contact your healthcare provider.
Interactions with cloNIDine HCl
Common Drug Interactions
- Alcohol and CNS depressants: Combining Clonidine with alcohol or other sedatives can increase the risk of excessive drowsiness, dizziness, and respiratory depression.
- Beta-blockers: Using Clonidine with beta-blockers can increase the risk of bradycardia and hypotension. When discontinuing one of these medications, consult your healthcare provider about adjusting your dose.
- Tricyclic Antidepressants (TCAs): These medications may reduce the effectiveness of Clonidine by increasing norepinephrine levels, potentially making blood pressure control less effective.
Alternatives to cloNIDine HCl
- Guanfacine (Intuniv): Another alpha-2 adrenergic agonist often used for ADHD and hypertension.
- Lisinopril (Zestril): An ACE inhibitor commonly used to manage high blood pressure.
- Atenolol (Tenormin): A beta-blocker that can help control high blood pressure and heart rate.
- SSRIs or Benzodiazepines: Often prescribed for anxiety or panic disorders as alternatives to Clonidine for these off-label uses.
