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Ciloxan
Ciloxan (generic name: Ciprofloxacin) is an antibiotic used to treat bacterial infections of the eye. It is commonly prescribed for conditions like bacterial conjunctivitis (pink eye) and corneal ulcers. Ciloxan belongs to the fluoroquinolone antibiotic class, and it works by inhibiting the bacterial enzymes necessary for DNA replication and repair, effectively killing the bacteria causing the infection. Ciloxan is available as an eye drop or ointment and is typically prescribed for short-term use to clear up infections and prevent complications.
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Frequently Asked Questions
How long does it take for Ciloxan to work?
Most patients start to see improvement within 1 to 3 days of starting treatment, but it is important to complete the full course of therapy as prescribed by your doctor.
Can I use Ciloxan while wearing contact lenses?
No, contact lenses should not be worn while using Ciloxan for an active eye infection. Wait at least 24 hours after completing treatment before resuming contact lens use.
What should I do if I miss a dose of Ciloxan?
If you miss a dose, apply it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Can Ciloxan be used for viral or fungal eye infections?
No, Ciloxan is an antibiotic and is only effective against bacterial infections. It will not work for viral or fungal infections. Your doctor will prescribe the appropriate treatment based on the type of infection.
Is Ciloxan safe for children?
Yes, Ciloxan is safe for use in children over the age of 1 year for treating bacterial conjunctivitis. Consult your pediatrician for proper dosing and usage instructions.
Comprehensive Drug Guide
How Does Ciloxan Work?
Ciloxan works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for bacterial DNA replication, transcription, repair, and recombination. By inhibiting these processes, Ciloxan effectively kills the bacteria, reducing the infection and preventing further bacterial growth.
What is Ciloxan Used For?
Common Dosages
Tablets: 250mg, 500mg, 750mg
- Oral solution: 10mg/mLEye drops (solution): 0.3% ciprofloxacin
- Ointment: 0.3% ciprofloxacin
Typical Dosing
- For bacterial conjunctivitis: Apply 1 to 2 drops in the affected eye every 2 hours while awake for the first 2 days, then reduce to every 4 hours for the next 5 days.
- For corneal ulcers: Apply 2 drops in the affected eye every 15 minutes for the first 6 hours, then reduce frequency as directed by the physician. The duration of treatment typically ranges from 7 to 14 days.
- For ointment: Apply a 1/2-inch ribbon of ointment into the affected eye 3 times a day for 7 days or as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Bacterial conjunctivitis (pink eye)
- Corneal ulcers caused by susceptible strains of bacteria
Off-Label Uses
Off-label uses: It's also used in the empirical treatment of febrile neutropenia and for its antimicrobial properties.
- Febrile neutropenia: 400mg every 8 hours.
Who Shouldn't Take Ciloxan?
- Hypersensitivity to ciprofloxacin or other fluoroquinolones
- Viral or fungal eye infections, as it is only effective against bacterial infections
Advice From The Pharmacist
- Wash your hands before applying Ciloxan to avoid contamination.
- Avoid touching the tip of the dropper or ointment tube to any surface, including your eye, to prevent contamination.
- Do not wear contact lenses while using Ciloxan for an eye infection.
- Continue using the medication for the full prescribed course, even if symptoms improve, to prevent bacterial resistance.
- If using both drops and ointment, apply the drops first, wait 5 to 10 minutes, and then apply the ointment.
Side Effects of Ciloxan
Common Side Effects
- Temporary stinging or burning in the eye after application
- Blurred vision
- Dry eyes
- Redness or discomfort
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, or difficulty breathing)
- Eye pain or swelling
- Vision changes
Risks and Warnings of Ciloxan
- Allergic Reactions: People allergic to ciprofloxacin or other quinolones should not use Ciloxan. Discontinue use immediately if an allergic reaction occurs.
- Superinfection: Prolonged use of Ciloxan may lead to secondary fungal or viral eye infections. Consult a doctor if symptoms worsen or do not improve.
- Contact Lens Wearers: Do not wear contact lenses while you have an active eye infection. Wait at least 24 hours after completing treatment before resuming contact lens use.
Interactions with Ciloxan
Common Drug Interactions
Ciloxan is used topically, and systemic drug interactions are unlikely. However, if you are using other eye medications, consult your doctor or pharmacist to determine the appropriate time intervals between applications to avoid dilution or interference.
Alternatives to Ciloxan
- Tobramycin (Tobrex): Another antibiotic eye drop used to treat bacterial infections.
- Ofloxacin (Ocuflox): A similar fluoroquinolone antibiotic for eye infections.
- Erythromycin Ointment: A commonly prescribed antibiotic ointment for eye infections.
- Moxifloxacin (Vigamox): Another fluoroquinolone antibiotic used for treating bacterial conjunctivitis.
