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Cequa

Cequa (cyclosporine ophthalmic solution) is a prescription eye drop used to treat dry eye disease. It works by reducing inflammation in the eyes, which can contribute to the discomfort and symptoms of dry eye. Cequa is particularly beneficial for patients with chronic dry eye who have not found relief with over-the-counter treatments. It helps to increase tear production in patients where tear production is presumed to be suppressed due to ocular inflammation.



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Frequently Asked Questions

How long does it take for Cequa to work?
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It may take 4 to 6 weeks for Cequa to start improving tear production and relieving symptoms. Full benefits may take longer with consistent use.

Can Cequa be used with contact lenses?
Open FAQClose FAQ

No, Cequa should not be applied while wearing contact lenses. Remove your lenses before applying the drops and wait at least 15 minutes before reinserting them.

What should I do if I miss a dose of Cequa?
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If you miss a dose, apply it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I use Cequa with other eye drops?
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Yes, but if you are using other eye drops, wait at least 15 minutes between applying Cequa and the other medication to avoid interference.

Is Cequa safe for long-term use?
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Cequa is generally considered safe for long-term use when prescribed by a healthcare provider. Regular monitoring and follow-up appointments with your healthcare provider are recommended to ensure the treatment remains effective.

Comprehensive Drug Guide

How Does Cequa Work?

Cequa contains cyclosporine, an immunosuppressant that reduces inflammation in the tear ducts. By decreasing inflammation, it helps improve the ability of the eye to produce tears, relieving the symptoms of dry eye disease.



What is Cequa Used For?

  • Treatment of chronic dry eye disease (keratoconjunctivitis sicca)


Common Dosages

Cequa is available by prescription in ophthalmic solution (eye drop) form and is not classified as a controlled substance.

Cequa is available in the following strength:

0.09% cyclosporine ophthalmic solution in single-use vials


Typical Dosing

FDA Approved Indications

The recommended dose of Cequa is one drop in each affected eye twice daily, approximately 12 hours apart. Continue using Cequa as prescribed, even if symptoms improve, to maintain tear production.


Who Shouldn't Take Cequa?

Cequa should not be used in individuals with:

  • Known hypersensitivity to cyclosporine or any other ingredient in the formulation
  • Active eye infections (bacterial, viral, or fungal)

Advice From The Pharmacist

  • Wash your hands before using Cequa. To avoid contamination, do not touch the tip of the vial to your eye or any other surface.
  • Cequa comes in single-use vials, which should be discarded after use. Do not reuse the vial, even if some solution remains.
  • Store Cequa vials at room temperature and protect them from light.
  • Cequa may take a few weeks to improve symptoms. Do not discontinue use prematurely unless directed by your healthcare provider.


Side Effects of Cequa

Common Side Effects

  • Eye burning or stinging upon administration
  • Redness or irritation
  • Blurred vision


Uncommon/Severe Side Effects

  • Signs of an allergic reaction (e.g., rash, swelling, difficulty breathing)
  • Eye pain or worsening vision


Risks and Warnings of Cequa

Eye Infections: Cequa is an immunosuppressant, which may slightly increase the risk of developing an eye infection. If you experience signs of infection (increased redness, pain, or discharge), contact your healthcare provider.

Delayed Onset of Action: It may take several weeks of regular use before Cequa begins to improve tear production and relieve symptoms. Use as directed and be patient with the treatment process.

Interactions with Cequa

Common Drug Interactions

Other ophthalmic medications: If using other eye drops, wait at least 15 minutes between applying Cequa and any other medications to prevent interference with absorption.

Contact lenses: Cequa should not be applied while wearing contact lenses. Remove lenses before applying the drops, and wait at least 15 minutes before reinserting them.

Alternatives to Cequa

  • Restasis (cyclosporine): Another cyclosporine-based ophthalmic solution used to treat chronic dry eye disease.
  • Xiidra (lifitegrast): An alternative prescription eye drop for dry eye disease that works by reducing inflammation differently than cyclosporine.
  • Over-the-counter artificial tears: Non-prescription solutions are used for mild cases of dry eye, though they may not be as effective for chronic cases.