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Brilinta
Ticagrelor belongs to the class of medications called platelet aggregation inhibitors, popularly known for their anti-clotting power. By preventing blood clots in people who had a heart attack, a stroke, or suffer from specific heart-related issues, Ticagrelor maintains the flow of blood to the heart. Common side effects can include breathlessness, increased bleeding, and minor bruising. Your healthcare provider will ensure the benefits of this drug outweigh these potential side effects.
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Frequently Asked Questions
Can Ticagrelor cause shortness of breath?
Yes, breathlessness is a known side effect of Ticagrelor. If it's severe or lasts long, contact your doc.
Should I take Ticagrelor with food?
You can take Ticagrelor with or without food. Just ensure you're consistent with how you take it to maintain stable blood levels.
Can I drink alcohol while taking Ticagrelor?
While alcohol doesn't directly interact with Ticagrelor, it can increase your risk of stomach bleeding. It's recommended to limit your alcohol intake while on this medication.
I missed a dose of Ticagrelor, what should I do?
If it's a short while until your next dose, skip the missed one. If there's a considerable time gap, take it as soon as you remember.
Can Ticagrelor be crushed or chewed?
Avoid crushing, chewing, or breaking the tablet. Swallow it whole with a full glass of water.
Comprehensive Drug Guide
How Does Brilinta Work?
Ticagrelor is an oral, reversible, direct-acting inhibitor of the adenosine diphosphate receptor P2Y12. Through this mechanism, the medication prevents platelet aggregation and minimizes the chance of clot formation, thus promoting a smooth and unrestricted blood flow.
What is Brilinta Used For?
FDA indications: Ticagrelor is primarily prescribed to reduce the chance of cardiovascular death, heart attack, or stroke in patients with either acute coronary syndrome (ACS) or a history of myocardial infarction (MI).
Off-label uses: Researchers are studying its potential efficacy in preventing recurrent stroke and acute ischemic stroke or transient ischemic attack.
Common Dosages
Tablets: 60mg, 90mg
Typical Dosing
FDA Approved Indications
- For FDA-approved indications:
- Acute Coronary Syndrome (ACS) or history of Myocardial Infarction (MI): Initial dose of 180mg followed by 90mg twice daily.
Off-Label Uses
- For off-label uses:
- Prevention of recurrent stroke: The d is yet to be determined conclusively and decided by a healthcare provider.
- Acute ischemic stroke or Transient Ischemic Attack (TIA): The d will depend on the severity and will be determined by the healthcare provider.
Who Shouldn't Take Brilinta?
- Those with active bleeding or a history of intracranial hemorrhage.
- Those having a history of intracranial aneurysm or vascular malformation.
- An individual on dialysis due to Severe Renal Dysfunction.
- Those with moderate to severe hepatic dysfunction.
- Those allergic to this medication or any of its components.
Advice From The Pharmacist
- Ensure consistency in taking this important med at the same each day.
- If you forgot your dose and it's closer to the next dose, skip the missed one. Never double up on your doses.
- Always take Ticagrelor with Aspirin, unless told otherwise by your healthcare provider.
- Be cautious during daily activities to avoid injury, as Ticagrelor could make you bleed more easily.
- Report any unusual bleeding or bruising to your doctor promptly.
- Before any surgery or dental work, inform your doctor or dentist you're taking Ticagrelor.
- Don?t stop taking this medicine without consulting your healthcare provider as stopping abruptly increases the risk of a heart attack or stroke.
Side Effects of Brilinta
Common Side Effects
- Breathlessness is a common side effect along with minor bruising and prolonged bleeding.
Uncommon/Severe Side Effects
- Rare side effects: You might notice blood in your urine or stools and cough up blood.
- Severe side effects: In dire situations, you could face fainting spells, excessive bleeding, irregular heartbeat, or changes in vision and speech.
Risks and Warnings of Brilinta
- Ticagrelor should not be used in the presence of active pathological bleeding or a history of intracranial hemorrhage due to the chance of potentially fatal bleeding.
- Patients with a bleeding disorder or those receiving procedures with bleeding risk should take extreme caution.
- Steer clear if you have moderate to severe liver disease as this drug could worsen the condition.
- If you're pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before starting this medication.
- If you are dealing with any form of kidney disease, take extra care due to the possible worsening of your condition under the influence of Ticagrelor.
Interactions with Brilinta
Common Drug Interactions
- Aspirin
- Rifampin
- Digoxin
- Statins (like atorvastatin, simvastatin)
- Opioids (like oxycodone, morphine)
Alternatives to Brilinta
- Aspirin
- Clopidogrel (Plavix)
- Prasugrel (Effient)
- Dipyridamole (Persantine)
