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Azurette
Azurette is a combination oral contraceptive that contains desogestrel (a progestin) and ethinyl estradiol (an estrogen). It is primarily used to prevent pregnancy by inhibiting ovulation, altering cervical mucus, and changing the uterine lining to prevent sperm from reaching the egg. Azurette is also sometimes prescribed to regulate menstrual cycles, reduce menstrual pain, and manage other hormonal-related issues, such as acne.
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Frequently Asked Questions
How effective is Azurette in preventing pregnancy?
When taken correctly, Azurette is over 99% effective in preventing pregnancy. However, its effectiveness may decrease if pills are missed or taken inconsistently.
Can Azurette help with acne?
Yes, Azurette can help improve mild to moderate acne by regulating hormonal fluctuations that may contribute to breakouts.
What should I do if I miss a dose of Azurette?
If you miss one active pill, take it as soon as you remember and take the next pill at your regular time (this may mean taking two pills in one day). If you miss two or more pills, follow the package instructions and use a backup form of contraception.
Is Azurette safe for long-term use?
Yes, Azurette is generally safe for long-term use. Regular checkups with your healthcare provider are recommended to ensure that it remains the best contraceptive option for you.
Can Azurette cause weight gain?
Some women may experience weight gain while taking Azurette, though this side effect varies from person to person. Most weight gain is typically due to water retention rather than fat gain.
Comprehensive Drug Guide
How Does Azurette Work?
- Inhibiting ovulation: The combination of desogestrel and ethinyl estradiol prevents the release of an egg from the ovaries.
- Altering cervical mucus: The hormone changes make it harder for sperm to enter the uterus.
- Changing the uterine lining: Azurette thins the uterine lining, making it less suitable for a fertilized egg to implant.
Common Dosages
- Tablets: 21 active tablets containing 0.15 mg desogestrel and 0.02 mg ethinyl estradiol, and 7 inactive placebo tablets.
Typical Dosing
- Take one active tablet daily for 21 consecutive days, followed by one placebo tablet daily for 7 days. Start a new pack after finishing the placebo tablets.
- It is important to take Azurette at the same time each day for maximum effectiveness.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy
- Regulation of menstrual cycles
- Management of menstrual pain (dysmenorrhea)
Who Shouldn't Take Azurette?
- History of blood clots, stroke, or heart attack
- Liver disease or liver tumors
- Known or suspected breast cancer or other estrogen-dependent cancers
- Uncontrolled high blood pressure
- Smokers over the age of 35, as it increases the risk of cardiovascular events
Advice From The Pharmacist
- Take Azurette at the same time every day to maintain effectiveness. If you miss a dose, follow the instructions provided in the package insert or consult your healthcare provider.
- Use a backup contraceptive method (e.g., condoms) for the first 7 days if this is your first time using Azurette or if you miss two or more pills.
- Azurette does not protect against sexually transmitted infections (STIs). Use additional protection, such as condoms, to prevent STIs.
Side Effects of Azurette
Common Side Effects
- Nausea
- Headaches
- Breast tenderness
- Mood changes
- Weight gain
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke or heart attack
- Liver problems (jaundice, liver tumors)
- Severe allergic reactions (swelling, rash, difficulty breathing)
Risks and Warnings of Azurette
- Increased cardiovascular risk: Smoking increases the risk of serious cardiovascular side effects, especially in women over 35 years of age.
- Blood clot risk: Azurette increases the risk of deep vein thrombosis (DVT), pulmonary embolism, stroke, or myocardial infarction, especially in smokers or women with a history of these conditions.
- Cancer risk: Azurette may increase the risk of developing breast cancer or cervical cancer in some women, particularly those with a family history of breast cancer.
Interactions with Azurette
Common Drug Interactions
- Antibiotics: Some antibiotics, such as rifampin, may reduce the effectiveness of Azurette.
- Anticonvulsants: Medications like phenytoin or carbamazepine may decrease the effectiveness of Azurette by increasing the metabolism of its hormones.
- St. John’s Wort: This herbal supplement may reduce the effectiveness of Azurette.
Alternatives to Azurette
- Ortho Tri-Cyclen (norgestimate/ethinyl estradiol): Another combination oral contraceptive that can also help with acne treatment.
- Lo Loestrin Fe (norethindrone/ethinyl estradiol): A low-dose contraceptive option.
- NuvaRing: A vaginal ring that delivers hormones for contraception.
- Depo-Provera (medroxyprogesterone acetate): A progestin-only injection given every three months to prevent pregnancy.
