Browse Medications by Drug Class: Non-Benzodiazepine Hypnotic (Z-Drug)

Written by Amar Lunagaria
Pharm.D • NiHowdy Founder

Reviewed by James Wong
Pharm.D • NiHowdy Founder
Published Jan 15, 2025

What are Non-Benzodiazepine Hypnotic (Z-Drug)?
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List of drugs in Non-Benzodiazepine Hypnotic (Z-Drug)
Drug Name | More Information | NiHowdy Prices & Bitcoin Rebate |
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Ambien | Ambien Information | Ambien Pricing |
Ambien CR | Ambien CR Information | Ambien CR Pricing |
Chloral Hydrate | Chloral Hydrate Information | Chloral Hydrate Pricing |
Edluar | Edluar Information | Edluar Pricing |
Eszopiclone | Eszopiclone Information | Eszopiclone Pricing |
Lunesta | Lunesta Information | Lunesta Pricing |
Zaleplon | Zaleplon Information | Zaleplon Pricing |
Zolpidem Tartrate | Zolpidem Tartrate Information | Zolpidem Tartrate Pricing |
Zolpidem Tartrate ER | Zolpidem Tartrate ER Information | Zolpidem Tartrate ER Pricing |
Zolpimist | Zolpimist Information | Zolpimist Pricing |
Brief history about Non-Benzodiazepine Hypnotic (Z-Drug)?
How do Non-Benzodiazepine Hypnotic (Z-Drug) work?
What are Non-Benzodiazepine Hypnotic (Z-Drug) used to treat?
Insomnia
Z-drugs like zolpidem and zaleplon are commonly prescribed to address difficulty falling asleep. Their rapid onset of action helps patients initiate sleep quickly, reducing frustration and improving sleep onset latency. For individuals struggling to stay asleep or waking up frequently during the night, medications like eszopiclone provide sustained effects to maintain sleep throughout the night, ensuring restorative rest. In cases where anxiety disrupts sleep, Z-drugs provide short-term relief by calming the overactive mind and promoting relaxation. This improves sleep quality and overall well-being.
Psychiatric Disorders
Z-drugs are occasionally used as adjuncts in the management of psychiatric conditions like depression or bipolar disorder, where insomnia is a significant symptom. By addressing sleep issues, they contribute to overall treatment success.
Who should consider Non-Benzodiazepine Hypnotic (Z-Drug) medications?
Adults
Adults experiencing short-term insomnia or sleep disturbances due to stress, lifestyle changes, or medical conditions benefit significantly from Z-drugs. These medications provide rapid relief from sleep issues, enhancing daily functioning and productivity. Healthcare providers tailor treatments to individual sleep patterns and needs.
Children
Z-drugs are not typically recommended for children due to a lack of safety data and potential side effects. However, in rare cases where insomnia significantly impacts health and development, these medications may be used under strict medical supervision and with pediatric-specific dosing.
Seniors
Seniors with insomnia may benefit from Z-drugs due to their targeted effects and shorter half-life, which reduce the risk of residual sedation. However, healthcare providers carefully monitor older adults for potential side effects, such as dizziness or confusion, to minimize fall risks and optimize safety.
Are Non-Benzodiazepine Hypnotic (Z-Drug) safe?
Can I take Non-Benzodiazepine Hypnotic (Z-Drug) during pregnancy?
Are Non-Benzodiazepine Hypnotic (Z-Drug) safe to take while lactating?
Are Non-Benzodiazepine Hypnotic (Z-Drug) controlled substances?
Side effects of Non-Benzodiazepine Hypnotic (Z-Drug)?
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