NiHowdy > Drug Classes > Aminoglycosides

Browse Medications by Drug Class: Aminoglycosides

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked

What are Aminoglycosides?

Aminoglycosides are a class of antibiotics used to treat serious bacterial infections caused by gram-negative bacteria and certain gram-positive bacteria. These medications work by disrupting bacterial protein synthesis, effectively stopping the growth and replication of bacteria. A unique characteristic of aminoglycosides is their potency against severe infections, including those resistant to other antibiotics. NiHowdy ensures affordable and reliable access to these life-saving medications, empowering patients to manage serious bacterial infections effectively.

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List of drugs in Aminoglycosides

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

Gentak	Gentak Information	Gentak Pricing
Gentamicin Sulfate	Gentamicin Sulfate Information	Gentamicin Sulfate Pricing
Tobramycin	Tobramycin Information	Tobramycin Pricing
Tobrex	Tobrex Information	Tobrex Pricing
Zelac	Zelac Information	Zelac Pricing

Brief history about Aminoglycosides?

Aminoglycosides were first discovered in the 1940s, with streptomycin being the first aminoglycoside introduced into clinical practice. This discovery marked a significant breakthrough in treating tuberculosis and other bacterial infections. Subsequent developments led to the creation of other aminoglycosides, such as gentamicin, amikacin, and tobramycin, which expanded the range of infections treatable by this class. Over the decades, aminoglycosides have remained critical in combating severe and resistant infections. NiHowdy simplifies access to these essential antibiotics, ensuring affordability and convenience for all patients.

How do Aminoglycosides work?

Aminoglycosides work by binding to bacterial ribosomes, disrupting the production of proteins necessary for bacterial growth and survival. This action leads to the death of the bacteria, making aminoglycosides bactericidal. For example, gentamicin is commonly used to treat bloodstream infections by targeting bacterial protein synthesis directly. NiHowdy provides affordable access to these potent antibiotics, ensuring patients receive effective treatment for serious infections.

What are Aminoglycosides used to treat?

Bloodstream Infections (Sepsis)

Aminoglycosides like gentamicin and amikacin are often used to treat severe bloodstream infections caused by gram-negative bacteria. These antibiotics act quickly to eliminate bacteria and prevent further complications.

Respiratory Infections

For infections such as pneumonia caused by gram-negative bacteria, aminoglycosides like tobramycin are used to target the pathogens directly, improving lung function and resolving symptoms.

Urinary Tract Infections (UTIs)

Aminoglycosides are effective in treating complicated UTIs, especially those caused by multidrug-resistant bacteria. They are often used in combination with other antibiotics for optimal efficacy.

Intra-Abdominal Infections

In cases of intra-abdominal infections, such as peritonitis, aminoglycosides are combined with other antibiotics to provide broad-spectrum coverage and eradicate bacteria.

Endocarditis

For bacterial endocarditis caused by certain gram-positive bacteria, aminoglycosides like gentamicin are used as part of combination therapy to improve treatment outcomes.

Skin and Soft Tissue Infections

Aminoglycosides are used in severe cases of skin and soft tissue infections, particularly those caused by resistant bacteria.

Who should consider Aminoglycosides medications?

Adults

Aminoglycosides are commonly prescribed for adults with severe bacterial infections, such as sepsis or pneumonia, particularly when caused by resistant gram-negative bacteria. These antibiotics are life-saving in critical care settings. NiHowdy ensures adults can access these treatments affordably and conveniently.

Children

In pediatric cases, aminoglycosides may be used to treat neonatal sepsis, meningitis, or other serious infections. Doses are carefully adjusted based on weight and age to ensure safety and efficacy. NiHowdy supports families with cost-effective solutions and reliable resources for managing pediatric bacterial infections.

Seniors

Seniors with bacterial infections benefit significantly from aminoglycosides, particularly when other antibiotics are ineffective. However, older adults require careful monitoring due to potential side effects, such as kidney or hearing issues. NiHowdy simplifies access to aminoglycosides for seniors, providing affordable options tailored to their unique needs.

Are Aminoglycosides safe?

Aminoglycosides are generally safe when prescribed and monitored carefully. Common side effects include mild gastrointestinal discomfort, while rare but serious risks include nephrotoxicity (kidney damage) and ototoxicity (hearing loss). Regular monitoring of kidney function and drug levels minimizes these risks. NiHowdy provides affordable access to aminoglycosides, ensuring patients receive expert-backed care to manage their conditions responsibly.

Can I take Aminoglycosides during pregnancy?

Aminoglycosides are generally avoided during pregnancy due to potential risks to the developing fetus, including hearing loss or kidney issues. However, they may be used in life-threatening situations where no safer alternatives are available. Patients should consult their healthcare provider for personalized advice. NiHowdy provides cost-effective access to expert guidance and alternative treatments for pregnant patients.

Are Aminoglycosides safe to take while lactating?

Aminoglycosides are generally considered safe during lactation, as their minimal absorption into breast milk reduces the risk of harm to the nursing infant. However, patients should consult their healthcare provider for specific recommendations. NiHowdy ensures affordable access to trusted information and safe treatment options for breastfeeding parents.

Are Aminoglycosides controlled substances?

Aminoglycosides are not classified as controlled substances but require a prescription due to their potential side effects and the need for careful monitoring. NiHowdy simplifies the prescription process, ensuring patients receive these critical antibiotics affordably and responsibly.

Side effects of Aminoglycosides?

Common side effects include nausea, diarrhea, and injection site reactions. Serious risks, such as nephrotoxicity (kidney damage) and ototoxicity (hearing loss), require regular monitoring and dose adjustments. Patients experiencing severe side effects should consult their healthcare provider immediately. NiHowdy helps patients manage these risks with expert-backed support and affordable care options.

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Cost considerations and insurance coverage for Aminoglycosides

The cost of aminoglycosides varies depending on the specific medication and formulation (e.g., intravenous or topical). Generic options are generally affordable, and many insurance plans cover these antibiotics. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these life-saving medications remain accessible and cost-effective.

How do I get rebates on Aminoglycosides?

NiHowdy's Bitcoin rebate program for aminoglycoside prescriptions offers patients a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing bacterial infections both affordable and rewarding, improving access to critical care while building long-term value.