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Zymaxid
Zymaxid (gatifloxacin) is a fluoroquinolone antibiotic used to treat bacterial eye infections, particularly bacterial conjunctivitis (pink eye). It works by stopping the growth of bacteria responsible for the infection. Zymaxid is effective against a variety of gram-positive and gram-negative bacteria, making it a broad-spectrum antibiotic for treating eye infections.
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Frequently Asked Questions
How long does it take for Zymaxid to work?
Improvement in symptoms of bacterial conjunctivitis typically occurs within a few days of starting treatment with Zymaxid, but it is important to complete the full course as prescribed to ensure the infection is fully eradicated.
Can Zymaxid cause blurred vision?
Yes, temporary blurred vision is a common side effect after using Zymaxid eye drops. This usually resolves quickly. If the blurred vision persists or worsens, contact your healthcare provider.
How should I store Zymaxid?
Zymaxid should be stored at room temperature, away from moisture and heat. Keep the bottle tightly closed when not in use and ensure it does not touch any surfaces to avoid contamination.
Can I wear contact lenses while using Zymaxid?
It is recommended to avoid wearing contact lenses while you have a bacterial eye infection. You should also avoid using contact lenses during treatment with Zymaxid, and only resume use after your doctor gives you the go-ahead.
What should I do if I miss a dose of Zymaxid?
If you miss a dose of Zymaxid, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not use two doses at the same time.
Comprehensive Drug Guide
How Does Zymaxid Work?
Zymaxid works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair in bacteria. By preventing these processes, Zymaxid effectively stops bacterial growth, helping to clear the infection in the eye.
Common Dosages
- Days 1 and 2: Instill 1 drop every 2 hours in the affected eye(s) while awake, up to 8 times per day.
- Days 3 to 7: Instill 1 drop 2-4 times per day in the affected eye(s).
Typical Dosing
- The typical dosing regimen involves frequent applications initially, with a gradual reduction in frequency as the infection improves. This helps ensure that the bacterial infection is completely eradicated.
Typical Dosing
FDA Approved Indications
- Bacterial conjunctivitis (pink eye) caused by susceptible strains of bacteria
Who Shouldn't Take Zymaxid?
- Known hypersensitivity to gatifloxacin, other fluoroquinolones, or any components of the formulation.
Advice From The Pharmacist
- Shake the bottle well before use.
- Instill the eye drops in the affected eye(s) as prescribed, and be careful not to touch the dropper tip to your eye or any surface to avoid contamination.
- If you are using other eye medications, wait at least 5 minutes between applications of different products.
- If you experience blurred vision after using Zymaxid, avoid driving or operating heavy machinery until your vision clears.
- Use Zymaxid for the full duration prescribed, even if symptoms improve before the infection is fully treated.
Side Effects of Zymaxid
Common Side Effects
- Temporary blurred vision
- Eye irritation (burning or stinging)
- Eye redness
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, hives, swelling of the face or throat)
- Eye pain or swelling
- Signs of a secondary fungal eye infection
Risks and Warnings of Zymaxid
- Superinfection: Prolonged use of Zymaxid can lead to overgrowth of non-susceptible organisms, including fungi. If a secondary infection develops, Zymaxid should be discontinued and appropriate treatment initiated.
- Allergic Reactions: Patients with a history of hypersensitivity to other fluoroquinolones may be at increased risk of allergic reactions to Zymaxid. Discontinue use if you experience signs of an allergic reaction.
Interactions with Zymaxid
Common Drug Interactions
- There are no significant systemic drug interactions with Zymaxid due to its topical application. However, it’s important to inform your healthcare provider about any other medications or eye treatments you are using, including over-the-counter products, to ensure safe use.
Alternatives to Zymaxid
- Vigamox (moxifloxacin): Another fluoroquinolone eye drop used to treat bacterial conjunctivitis.
- Tobramycin ophthalmic solution: An antibiotic used for eye infections, particularly in cases where fluoroquinolones are not appropriate.
- Besivance (besifloxacin): Another fluoroquinolone eye drop that may be used as an alternative for bacterial eye infections.
