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Besivance
Besivance (besifloxacin) is a fluoroquinolone antibiotic used to treat bacterial conjunctivitis (commonly known as pink eye). It is specifically formulated as an ophthalmic suspension (eye drops) and works by inhibiting the growth of bacteria that cause eye infections. Besivance is effective against a broad range of gram-positive and gram-negative bacteria, making it a valuable treatment for bacterial eye infections.
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Frequently Asked Questions
How long does it take for Besivance to work?
Most patients begin to notice an improvement in symptoms within a few days of starting treatment, but it's important to complete the full course of the medication to ensure the infection is fully cleared.
Can I use Besivance if I wear contact lenses?
No, contact lenses should not be worn during the treatment of bacterial conjunctivitis. You may resume wearing lenses 15 minutes after the application of the drops, but only after your doctor advises that the infection has cleared.
What should I do if I miss a dose?
If you miss a dose, use it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double up doses.
Can Besivance be used for viral eye infections?
No, Besivance is only effective against bacterial infections and will not work for viral infections, such as viral conjunctivitis.
Is Besivance safe for children?
Yes, Besivance is approved for use in children aged 1 year and older for the treatment of bacterial conjunctivitis. Always follow your doctor’s instructions when using this medication for children.
Comprehensive Drug Guide
How Does Besivance Work?
Besivance works by inhibiting DNA gyrase and topoisomerase IV, enzymes that bacteria need to replicate their DNA and divide. By blocking these enzymes, Besivance prevents bacterial replication, thereby reducing the bacterial load in the eye and helping to resolve the infection.
Common Dosages
- 0.6% ophthalmic suspension
Typical Dosing
- The usual dose is one drop of Besivance in the affected eye(s) three times daily (approximately 4 to 12 hours apart) for 7 days, or as directed by your healthcare provider.
Typical Dosing
FDA Approved Indications
- Bacterial conjunctivitis (eye infections caused by susceptible bacteria)
Who Shouldn't Take Besivance?
- Known hypersensitivity to besifloxacin, quinolones, or any other components of the formulation.
Advice From The Pharmacist
- Shake the bottle well before each use to ensure the medication is properly mixed.
- Avoid touching the tip of the dropper to any surface (including the eye) to prevent contamination.
- If you wear contact lenses, remove them before using Besivance and wait at least 15 minutes after application before reinserting them, as the medication may interact with the lenses.
- Complete the full course of treatment even if symptoms improve before finishing the medication to ensure the infection is fully treated.
Side Effects of Besivance
Common Side Effects
- Eye redness
- Blurred vision
- Eye discomfort
- Headache
Uncommon/Severe Side Effects
- Severe allergic reactions (such as swelling, rash, or difficulty breathing)
- Corneal deposits (rare)
Risks and Warnings of Besivance
- Bacterial resistance: As with other antibiotics, improper use or overuse of Besivance can lead to bacterial resistance. Be sure to use it only as prescribed and complete the full course of treatment.
- Hypersensitivity reactions: If you experience swelling, rash, or difficulty breathing after using Besivance, discontinue use and seek medical attention immediately.
Interactions with Besivance
Common Drug Interactions
- Other ophthalmic medications: If you are using other eye drops, wait at least 5 minutes between applying different medications to allow each to be absorbed properly.
- Contact lenses: Avoid wearing contact lenses during the treatment of bacterial conjunctivitis, as the infection or the medication may interact with the lenses.
Alternatives to Besivance
- Vigamox (moxifloxacin): Another fluoroquinolone antibiotic used to treat bacterial conjunctivitis.
- Tobradex (tobramycin/dexamethasone): A combination antibiotic and corticosteroid for treating bacterial eye infections.
- Polytrim (polymyxin B/trimethoprim): A combination antibiotic used to treat bacterial conjunctivitis and other eye infections.
